Novel Antibody May Reduce Amyloid, Cut AD Symptoms

Lecanemab can reduce amyloid plaques within the first months after treatment initiation and is linked to improved clinical signs in as early as 6 months, updates from a phase 2 trial show.
Medscape Medical News

source https://www.medscape.com/viewarticle/971975?src=rss

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New AAFP practice guideline sets blood pressure targets for adults with hypertension

From 1977 to 2003, seven Joint National Committees (JNC), sponsored by the National Heart, Lung, and Blood Institute (NHLBI), produced consensus multi-specialty guidelines on the diagnosis and management of hypertension. In 2013, well into the development of JNC8, the NHLBI abruptly turned the process over to the American College of Cardiology/American Heart Association (ACC/AHA). The JNC8 committee independently published an evidence-based guideline in JAMA that raised the blood pressure treatment threshold in most older adults from 140/90 to 150/90 mm Hg. Concerned about conflicts of interest and other deviations from Institute of Medicine-recommended practices for developing trustworthy guidelines , primary care groups, including the American Academy of Family Physicians (AAFP), declined to participate in the ACC/AHA guideline panel. And the longstanding edifice of hypertension guidelines fractured. In 2017, the ACC/AHA released its clinical practice guideline , which most notab...
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