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Showing posts from May, 2026

Psilocybin May Boost Abstinence in Cocaine Use Disorder

Psilocybin added to psychotherapy is associated with a greater likelihood of abstinence in cocaine use disorder than an adjunct active placebo, a study shows. Medscape Medical News source https://www.medscape.com/viewarticle/psilocybin-may-boost-abstinence-cocaine-use-disorder-2026a1000i3c?src=rss

Antibiotic Effects on the Gut Detected Up to 8 Years Later

Changes in gut microbiome diversity are observed with certain antibiotic drugs years later, even after just one course of therapy. Medscape Medical News source https://www.medscape.com/viewarticle/antibiotic-effects-gut-detected-8-years-later-2026a1000i3a?src=rss

Kids’ Food Allergy May Take an Emotional Toll on Parents

Parents of children with food allergies may experience a greater psychosocial burden when reactions are more frequent or severe and when families follow stricter allergenic food avoidance practices. Medscape Medical News source https://www.medscape.com/viewarticle/kids-food-allergy-may-take-emotional-toll-parents-2026a1000i35?src=rss

Will PROTEUS Change the Playbook for Radical Prostatectomy?

New data now show that perioperative systemic therapy with apalutamide can improve outcomes after radical prostatectomy. Medscape Medical News source https://www.medscape.com/viewarticle/will-proteus-change-playbook-radical-prostatectomy-2026a1000i2k?src=rss

Abemaciclib Slows Progression of Advanced Liposarcoma

In a phase 3 trial of patients with dedifferentiated liposarcoma, the CDK4/6 inhibitor extended progression-free survival more than sixfold. Medscape Medical News source https://www.medscape.com/viewarticle/abemaciclib-slows-progression-advanced-liposarcoma-2026a1000i2g?src=rss

Selpercatinib Cuts Recurrence Risk in Early RET+ NSCLC

In the first phase 3 trial of a RET inhibitor as adjuvant therapy, selpercatinib markedly improved event-free survival vs placebo in early-stage RET fusion-positive NSCLC. Medscape Medical News source https://www.medscape.com/viewarticle/selpercatinib-cuts-recurrence-risk-early-ret-non-small-cell-2026a1000i25?src=rss

Doctor Helps Woman Stop Blaming Herself and Accept Treatment

When an oncologist learns one patient’s story, everything shifts, including his approach to consultations. Medscape Medical News source https://www.medscape.com/viewarticle/doctor-helps-woman-stop-blaming-herself-and-accept-treatment-2026a1000i20?src=rss

Tile-Based Radiation to Treat Large Brain Metastases?

The GammaTile may improve outcomes over standard stereotactic RT after resection of large brain metastases, but a striking overall survival benefit in a phase 3 trial raises questions. Medscape Medical News source https://www.medscape.com/viewarticle/tile-based-radiation-treat-large-brain-metastases-2026a1000i1s?src=rss

Treat the Overlap Between Long COVID and Chronic Fatigue

As more patients seek help for myalgic encephalomyelitis/chronic fatigue syndrome and similar symptoms for long COVID, primary care clinicians play a bigger role in treatment. Medscape Medical News source https://www.medscape.com/viewarticle/physicians-are-undertreating-chronic-fatigue-they-could-2026a1000hwg?src=rss

Don’t Ignore Mild Asthma in Children

Mild childhood asthma is often missed, risking impaired lung growth, fixed airflow obstruction and future COPD; early diagnosis and control can prevent lasting harm. Medscape Medical News source https://www.medscape.com/viewarticle/dont-ignore-mild-asthma-children-2026a1000hwf?src=rss

Add-On Alteplase May Aid Stroke Recovery Post-Thrombectomy

Adjunctive intra-arterial alteplase after successful thrombectomy may aid functional recovery compared to thrombectomy alone in large vessel occlusion stroke, new data show. Medscape Medical News source https://www.medscape.com/viewarticle/add-alteplase-may-aid-stroke-recovery-post-thrombectomy-2026a1000hr9?src=rss

HEARTS 2.0: PAHO's 38-Step Pathway for Cardio-Renal Care

Backed by 26 ministries and GRADE evidence, PAHO's new clinical pathway could accelerate access to SGLT2 inhibitors and statins to curb cardiorenal complications. Medscape News Global source https://www.medscape.com/viewarticle/hearts-2-0-pahos-38-step-pathway-cardio-renal-care-2026a1000hk1?src=rss

Older Age Tied to Higher CT Positivity in Abdominal Pain

Older adults visiting the emergency department for abdominal pain have higher risks for CT positivity and hospital admission than younger adults, despite less specific symptoms. Medscape Medical News source https://www.medscape.com/viewarticle/older-age-tied-higher-ct-positivity-abdominal-pain-2026a1000heb?src=rss

Is Venetoclax Retreatment Effective in Relapsed CLL?

Researchers review available clinical evidence for retreatment with venetoclax, alone or in combination, in patients with relapsed chronic lymphocytic leukemia. Medscape Medical News source https://www.medscape.com/viewarticle/venetoclax-retreatment-effective-relapsed-cll-2026a1000he0?src=rss

Interface Lets Paralyzed Patient 'Type' Faster than Ever

A paralyzed patient nearly matched the words per minute the average person can type on their phone, with 95% accuracy. See how brain-computer interface has improved. Medscape Medical News source https://www.medscape.com/viewarticle/new-interface-lets-paralyzed-patient-type-faster-than-ever-2026a1000hd9?src=rss

How to Boost CRC Screening Uptake in the Community

Programs that support patients in the screening process or mail stool test kits to their homes are most effective at boosting colorectal cancer screening rates. Medscape Medical News source https://www.medscape.com/viewarticle/how-boost-crc-screening-uptake-community-2026a1000h3u?src=rss

FDA Approves Bulevirtide for Hepatitis Delta Virus

Bulevirtide (Hepcludex; Gilead Sciences, Inc.) is the first FDA-approved treatment for chronic hepatitis delta virus infection. Medscape Medical News source https://www.medscape.com/viewarticle/fda-approves-bulevirtide-hepatitis-delta-virus-2026a1000h3x?src=rss

What’s in the Axial Spondyloarthritis Treatment Pipeline?

Most available drugs are effective for symptom control and structural protection, but they’re not perfect and new agents are being investigated to help close the treatment gap. Medscape Medical News source https://www.medscape.com/viewarticle/whats-axial-spondyloarthritis-treatment-pipeline-2026a1000gyu?src=rss

Expert Guidance on Stacking Systemic Therapies for Psoriasis

Advice on when and how to switch or stack treatments can help in cases of an incomplete or waning response. Medscape Medical News source https://www.medscape.com/viewarticle/expert-guidance-switching-stacking-systemic-therapies-2026a1000gyp?src=rss

GLP-1s Tied to Weight Loss in Real-World Rheumatologic Care

Semaglutide and tirzepatide use is rising among patients with rheumatic and musculoskeletal diseases and is linked to meaningful 1-year weight loss, especially in tirzepatide users. Medscape Medical News source https://www.medscape.com/viewarticle/glp-1s-tied-weight-loss-real-world-rheumatologic-care-2026a1000gmt?src=rss

Can Intraperitoneal Paclitaxel Improve OS in Gastric Cancer?

A phase 3 trial explores whether adding intraperitoneal paclitaxel to intravenous paclitaxel plus S-1 improves overall survival in patients with gastric cancer and peritoneal metastasis. Medscape Medical News source https://www.medscape.com/viewarticle/can-intraperitoneal-paclitaxel-improve-survival-gastric-2026a1000gmg?src=rss

How NPs Are Navigating Prior Authorization Coverage Barriers

The same hurdles facing physicians slow treatment for nurse practitioners’ patients, and the impact on care continues. Medscape Medical News source https://www.medscape.com/viewarticle/how-nps-are-navigating-prior-authorization-coverage-barriers-2026a1000gm0?src=rss

Spain’s Debate Over Obstetric Violence

Health leaders in Spain debate balancing maternal-fetal safety with respectful, informed care, spotlighting birth plans, staffing shortages and calls for public outcome reporting. Medscape News Europe source https://www.medscape.com/viewarticle/spains-debate-over-obstetric-violence-2026a1000gfv?src=rss

NP-Led Outreach Ups Cancer Screening in Rural Women Veterans

A nurse practitioner-led outreach program improves the rates of breast and cervical cancer screening among women veterans in rural areas, a retrospective study shows. Medscape Medical News source https://www.medscape.com/viewarticle/nurse-practitioner-led-outreach-boosts-cancer-screening-2026a1000gfi?src=rss

Primary Care Making More Mental Health Diagnoses for Kids

Pediatric mental health visits in primary care surged over a 9-year period. Medscape Medical News source https://www.medscape.com/viewarticle/primary-care-making-more-mental-health-diagnoses-kids-2026a1000g9x?src=rss

Revolutionary Cancer Tx Could Transform Autoimmune Disease

Researchers are testing CAR T-cell therapy as a way to reset the immune system in lupus, Graves’ disease and other conditions where the body’s defenses go rogue. Knowable Magazine source https://www.medscape.com/s/viewarticle/revolutionary-cancer-treatment-could-transform-autoimmune-2026a1000g9o?src=rss

Mirvetuximab Signals a New Era in Ovarian Care

Mirvetuximab’s approval for FR alpha-positive, platinum-resistant disease marks a precision-medicine milestone, opening opportunities for ADCs while highlighting the need for assay standardization and safety plans. Medscape News Europe source https://www.medscape.com/viewarticle/mirvetuximab-signals-new-era-ovarian-care-2026a1000g48?src=rss

Hydronephrosis on USG Predicts Stones but May Not Cut CT Use

Hydronephrosis identified on point-of-care ultrasound is linked to higher risks for stone disease and early urologic intervention in suspected renal colic but not with reduced CT use or ED stays. Medscape Medical News source https://www.medscape.com/viewarticle/hydronephrosis-renal-point-care-ultrasound-predicts-stones-2026a1000fvn?src=rss

Hidradenitis Suppurativa Tied to Higher Cardiovascular Risks

Individuals with HS show higher risks for cardiovascular outcomes, including hypertension, coronary or ischemic heart disease, venous thromboembolism, and myocardial infarction, in a meta-analysis. Medscape Medical News source https://www.medscape.com/viewarticle/hidradenitis-suppurativa-linked-increased-cardiovascular-2026a1000fw3?src=rss

Screening for testicular cancer is ineffective

In adolescent and young adult males, palpation of the testicles for signs of cancer has traditionally been part of the preparticipation sports physical or well-child examination. Unlike most malignancies that predominantly affect older adults, testicular cancer is most commonly diagnosed between 15 and 34 years of age . Nonetheless, screening for testicular cancer has long been something I have discouraged my students and residents from doing. The rationale is twofold: it's rare, so screening will lead to many false positives and unnecessary evaluations; and more importantly, it's curable even at advanced stages, so earlier detection provides little to no incremental benefit. These were the reasons why in 2011, the U.S. Preventive Services Task Force (USPSTF)  reaffirmed its previous recommendation against testicular cancer screening , based on an evidence review that I co-authored that found no new evidence to change this conclusion. Others have dissented over the years. They...

Housing Instability Tied to Lower Rates of CRC Screening

Unmet health-related social needs, especially housing instability and transportation barriers, are linked to lower rates of screening for colorectal cancer among US adults. Medscape Medical News source https://www.medscape.com/viewarticle/housing-instability-tied-lower-rates-screening-colorectal-2026a1000fq8?src=rss

Implanted Islet Cell Device Could Control Glucose for Weeks

Researchers developed a battery-free device the size of a coin that can deliver islet cells in the body and keep them healthy, no immunosuppression required. Medscape Medical News source https://www.medscape.com/viewarticle/implanted-islet-cell-device-could-control-glucose-weeks-2026a1000fjv?src=rss

Optimal Sleep May Lower Dementia Risk in Focal Epilepsy

Optimal sleep duration is tied to better cognition and a lower risk for dementia in adults with focal epilepsy than in healthy individuals, new research shows. Medscape Medical News source https://www.medscape.com/viewarticle/optimal-sleep-may-lower-dementia-risk-focal-epilepsy-2026a1000fjr?src=rss

How Bariatric Surgery Shapes IBD Risk Over Time in Obesity

In patients with severe obesity, metabolic and bariatric surgery was linked to a lower risk for inflammatory bowel disease within 3 years but a higher risk over longer follow-up. Medscape Medical News source https://www.medscape.com/viewarticle/how-bariatric-surgery-shapes-ibd-risk-over-time-obesity-2026a1000fjj?src=rss

Telerehabilitation May Support Stroke Recovery at Home

Remote rehabilitation programs improve mobility, balance, and quality of life after stroke, with added benefits in adherence and patient satisfaction. Medscape News Europe source https://www.medscape.com/viewarticle/telerehabilitation-may-support-stroke-recovery-home-2026a1000fe9?src=rss

Can Gut Bacterium Supplement Lead to Less Weight Regain?

Daily supplementation with pasteurized Akkermansia muciniphila MucT after weight loss leads to less weight regain than placebo in adults with overweight or obesity. Medscape Medical News source https://www.medscape.com/viewarticle/can-gut-bacterium-supplement-lead-less-weight-regain-2026a1000fdy?src=rss

Sigmoidoscopy Cuts Colorectal Cancer Risk in Men

Researchers randomly assign more than 100,000 adults without CRC to receive once-only sigmoidoscopy screening or no screening between 1999 and 2001. Here’s what they find. Medscape Medical News source https://www.medscape.com/viewarticle/sigmoidoscopy-cuts-colorectal-cancer-risk-men-2026a1000f7b?src=rss

Combo Therapy Boosts Early CML Response but Not Long Term

A phase 3 trial evaluates the efficacy and safety of nilotinib with pegylated interferon alfa-2a in patients with newly diagnosed chronic-phase chronic myeloid leukemia. Medscape Medical News source https://www.medscape.com/viewarticle/combo-therapy-boosts-early-cml-response-not-long-term-2026a1000f6z?src=rss

Exclusive-Kennedy's Health Officials Explored US Ban Of Some Widely Used Antidepressants, Sources Say

U.S. health department officials last week explored whether they could ban certain drugs in a widely prescribed class of antidepressants as Health Secretary Robert F.... Reuters Health Information source https://www.medscape.com/s/viewarticle/exclusive-kennedys-health-officials-explored-us-ban-some-2026a1000exu?src=rss

UK Tops Global Seizures in Illicit Medicine Crackdown

The UK seized over two million illicit medicine doses in March — more than any other country in a 90-nation INTERPOL crackdown that netted 6.42 million doses globally. Medscape News UK source https://www.medscape.com/viewarticle/uk-tops-global-seizures-illicit-medicine-crackdown-2026a1000eyx?src=rss

Could AI Copilots Reduce Clinician Documentation Time?

Ambient AI systems may reduce documentation demands and allow physicians to spend more time interacting directly with patients during their visits. Medscape News Europe source https://www.medscape.com/viewarticle/could-ai-copilots-reduce-clinician-documentation-time-2026a1000ets?src=rss

Nicotinamide Linked to Lower Melanoma Risk Post Skin Cancer

Nicotinamide supplementation confers a statistically significant risk reduction for melanoma in patients with a prior nonmelanoma skin cancer, a cohort study finds. Medscape Medical News source https://www.medscape.com/viewarticle/nicotinamide-linked-lower-melanoma-risk-patients-previous-2026a1000etj?src=rss

Migraine Tied to Lower Dementia, Alzheimer’s Risk

Migraine is linked to a 30% lower risk for dementia and a 42% lower risk for Alzheimer’s disease than not having migraine, a new cohort study shows. Medscape Medical News source https://www.medscape.com/viewarticle/migraine-tied-lower-dementia-alzheimers-risk-2026a1000et8?src=rss

Anti-TNF May Reduce Kidney Injury in Brain Death Donors

Researchers identify TNF driven injury pathways in brain death donors and test anti-TNF therapy to improve kidney graft quality before transplantation. Medscape News Europe source https://www.medscape.com/viewarticle/anti-tnf-may-reduce-kidney-injury-brain-death-donors-2026a1000enq?src=rss

Obesity Subtypes Predict Poor Physical Function in Knee OA

Obesity and low muscle mass and/or cardiometabolic comorbidities impede physical functioning more than obesity alone in individuals with or at risk for knee osteoarthritis. Medscape Medical News source https://www.medscape.com/viewarticle/obesity-subtypes-predict-poor-physical-function-knee-oa-2026a1000enk?src=rss

Questions Persist Over Echinacea for Preventing Colds

Evidence on echinacea for the prevention or treatment of respiratory infections remains inconsistent, with product variability limiting clear clinical guidance. Medscape News Global source https://www.medscape.com/viewarticle/questions-persist-over-echinacea-preventing-colds-2026a1000enb?src=rss

Why Scientists Put a Tiny Elephant Inside a Living Cell

A joke between researchers turned into the first structure 3D-printed inside a living cell, a precursor to building microscopic machines within cells. Medscape Medical News source https://www.medscape.com/viewarticle/why-scientists-put-tiny-elephant-inside-living-cell-2026a1000egm?src=rss

Cervical Cancer Screening Gaps Persist After 65 Years of Age

Most women requiring continued cervical cancer screening — including those at high risk — do not continue screening after 65 years of age. Medscape Medical News source https://www.medscape.com/viewarticle/cervical-cancer-screening-gaps-persist-after-65-years-age-2026a1000egi?src=rss

Most NMIBC Recurrences Seen in BCG-Exposed Patients

A large real-world study examines outcomes and treatment patterns among patients with non-muscle-invasive bladder cancer treated with BCG. Medscape Medical News source https://www.medscape.com/viewarticle/most-nmibc-recurrences-seen-bcg-exposed-patients-2026a1000eg6?src=rss

Extent of Family History Not Tied to Pancreatic Cancer Risk

The number of family relatives, first-degree or not, who have pancreatic cancer does not appear to affect the risk for intermediate lesions. Medscape Medical News source https://www.medscape.com/viewarticle/extent-family-history-not-tied-pancreatic-cancer-risk-2026a1000ean?src=rss

Study Finds Microplastics Near Tumors; Experts Doubt Results

Using LDIR, O PTIR, Py GC/MS, and SEM, researchers quantified MNPs in 191 brain samples, but experts question the unusually high particle masses and urge methodological validation. Medscape News Europe source https://www.medscape.com/viewarticle/study-finds-microplastics-near-tumors-experts-doubt-results-2026a1000ea7?src=rss

Fatigue is Finally a Surgical Safety Issue

As new tech and changing norms drive fatigue mitigation, the moment is ripe to prioritize patient safety (and yours) by recognizing when you’re too tired to operate — and speaking up. Medscape Medical News source https://www.medscape.com/viewarticle/fatigue-finally-surgical-safety-issue-2026a1000e9w?src=rss

Missed Sexual Health Assessment May Limit Clinical Insight

New data show strong links between chronic disease, sexual dysfunction, and loneliness, highlighting missed opportunities for holistic patient evaluation. Medscape News Europe source https://www.medscape.com/viewarticle/missed-sexual-health-assessment-may-limit-clinical-insight-2026a1000e4i?src=rss

Baveno Criteria May Reduce Endoscopy Burden in Cirrhosis

The Baveno VI criteria show high sensitivity for ruling out clinically significant portal hypertension and high-risk varices in patients with cirrhosis. Medscape Medical News source https://www.medscape.com/viewarticle/baveno-criteria-may-reduce-endoscopy-burden-patients-2026a1000e40?src=rss

Gray Market Peptides: So Much Hype, So Little Data

RFK Jr and Joe Rogan use them to heal, and NASA wants to put one in the astropharmacy. But without extensive data on humans, what should you tell patients about peptides? Medscape Medical News source https://www.medscape.com/viewarticle/gray-market-peptides-so-much-hype-so-little-data-2026a1000dzg?src=rss

FDA OKs First Non-Antipsychotic for Alzheimer’s Agitation

The FDA has approved Auvelity for AD agitation. The combination of dextromethorphan and bupropion is the first oral non-antipsychotic approved for this indication. Medscape Medical News source https://www.medscape.com/viewarticle/fda-oks-first-non-antipsychotic-alzheimers-agitation-2026a1000dze?src=rss