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Showing posts from December, 2022

Heart Benefits Begin at Well Under 10,000 Daily Steps

Taking more steps per day is associated with progressively lower risk of heart disease, but the benefits are seen at fewer than 10,000 steps per day, new research suggests. Medscape Medical News source https://www.medscape.com/viewarticle/986371?src=rss

Congressional Report: FDA Broke Own Protocols in Approving Biogen Alzheimer's Drug

The FDA failed to adhere to its own guidance and internal practices during the approval process for Biogen's Alzheimer's drug Aduhelm, which was 'rife with irregularities,' a congressional report showed on Thursday. Reuters Health Information source https://www.medscape.com/viewarticle/986319?src=rss

Menstrual Disorders Linked With Cardiovascular Disease Risk

Certain characteristics of the menstrual cycle across a woman's reproductive life span may constitute additional risk factors for cardiovascular disease, according to researchers. Medscape Medical News source https://www.medscape.com/viewarticle/986364?src=rss

Exacerbation History Found Flawed as COPD Risk Predictor

Exacerbation history alone wasn't as effective as risk-prediction models for predicting exacerbation in chronic obstructive pulmonary disease. Medscape Medical News source https://www.medscape.com/viewarticle/986363?src=rss

What Are the Current and Future Challenges in Obesity?

Priorities for obesity management include recognizing the chronicity of the disease, combating the stigma associated with it, and starting treatment early, according to experts. Medscape Medical News source https://www.medscape.com/viewarticle/986362?src=rss

Genetic Test Identifies Parental Source of Cancer Variant

A new test can determine whether an inherited disease gene variant came from a patient's mother or father. Medscape Medical News source https://www.medscape.com/viewarticle/986360?src=rss

Physicians React: Right Path Now With Pain Management, Opioids?

Doctors give opinions about whether their profession is being over- or under-aggressive with pain management, especially where prescription of opioids is concerned. Medscape Medical News source https://www.medscape.com/viewarticle/986356?src=rss

Strong Link Between Muscle Strength, Mobility and Brain Health

Higher handgrip strength and better mobility correlate with larger brain volumes in cognitively impaired adults with biomarker evidence of dementia. Medscape Medical News source https://www.medscape.com/viewarticle/986312?src=rss

Study Evaluates Alopecia Areata Features in Hispanic Population

In the study, the most common comorbidity in patients overall was atopy, including allergic rhinitis, asthma, and/or atopic dermatitis. MDedge News source https://www.medscape.com/viewarticle/986310?src=rss

FDA Serotonin Syndrome Warning Unnecessary?

Although the antibiotic linezolid carries a warning against its use by patients taking antidepressants, owing to risk for serotonin syndrome, new research suggests that that concern may be unnecessary. Medscape Medical News source https://www.medscape.com/viewarticle/986307?src=rss

Nursing Exam Failure Rates Spark Review of Test Results

Nursing students in Quebec protest a high failure rate this year, while US nursing test examiners have noticed that passing rates have dropped since the pandemic began. Medscape Medical News source https://www.medscape.com/viewarticle/986303?src=rss

AI Could Predict Failure of Treatment for Brain Metastases

A novel artificial intelligence-based tool predicted treatment failure with 83% accuracy after analyzing baseline treatment-planning MRIs. Medscape Medical News source https://www.medscape.com/viewarticle/986306?src=rss

Bands, Choirs, and Orchestras Teach Kids Resiliency

Group music making -- such as in a choir, orchestra, or band -- is a good way to teach kids how to face adversity. Quick Take source https://www.medscape.com/viewarticle/986298?src=rss

Kiwifruit Found Effective for Constipation

The fruit beat psyllium in treating functional constipation and matched it in treating constipation-predominant irritable bowel syndrome. Medscape Medical News source https://www.medscape.com/viewarticle/986297?src=rss

Do Doctors Dismiss Endometriosis-Related Pain During Sex?

Women with sexual problems express the desire for better information — and for their gynecologists to initiate the conversation. Medscape Medical News source https://www.medscape.com/viewarticle/986265?src=rss

Contraceptive Testicular Rings: How Well Are They Tolerated?

About 80% of participants in a small study experienced minor adverse effects, and three stopped using the device for reasons of tolerability. Medscape Medical News source https://www.medscape.com/viewarticle/986261?src=rss

Sexual Assault Allegations Lead to Arrest of Gastroenterologist

A gastroenterologist affiliated with the Cleveland Clinic has been arrested and charged with sexually assaulting three women during liver examinations. Medscape Medical News source https://www.medscape.com/viewarticle/986251?src=rss

Three Deaths in France Linked to Group A Strep Infections

Several children without identified risk factors have been hospitalized after contracting an invasive group A strep infection. Medscape Medical News source https://www.medscape.com/viewarticle/986245?src=rss

Longer Survival Not Top Priority for Some Patients With Cancer

Patients with neuroendocrine tumors place a higher priority on quality-of-life factors than longer survival but often feel that their doctors are not aligned with their views. Medscape Medical News source https://www.medscape.com/viewarticle/986242?src=rss

Few Complications With Excimer Laser Retrieval of IVC Filters

Excimer laser sheath–assisted retrieval of embedded inferior vena cava filters was safe and effective in a multicenter study. Medscape Medical News source https://www.medscape.com/viewarticle/986209?src=rss

Six Obstacles in Breast Cancer Detection and Treatment

At a recent conference, oncologists outlined key challenges that need to be addressed to improve breast cancer diagnosis and treatment. Medscape Medical News source https://www.medscape.com/viewarticle/986208?src=rss

Music Improves Quality of Life for Patients With Dementia

A program in Germany found that music promoted relaxation, improved mood, and strengthened social communication for patients with dementia. Medscape Medical News source https://www.medscape.com/viewarticle/986206?src=rss

What Consequences Has the Pandemic Had for Brazilian Youth?

A book published by the Oswaldo Cruz Foundation aims to help healthcare professionals create strategies to improve the care provided to young adults. Medscape Medical News source https://www.medscape.com/viewarticle/986203?src=rss

Higher Type 1 Diabetes Glycemia Links to More Preeclampsia

Women with type 1 diabetes and higher A1c levels around the time of conception had higher rates of preeclampsia during pregnancy. First Look source https://www.medscape.com/viewarticle/986200?src=rss

Popular Scrubs Maker Defeats Competitor in Court

Fast-growing medical scrubs company Figs just beat back a lawsuit from a competing medical apparel maker and now faces new investor lawsuits. But that's just background noise for fans of the scrubs. Medscape Medical News source https://www.medscape.com/viewarticle/986166?src=rss

My favorite public health and health care books of 2022

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My Christmas post is the 7th in an annual series listing my 10 favorite public health and health care reads of the past year. Not all of these were first published in 2022. Happy holidays and warm wishes for a healthy and rewarding New Year! ** 1.  Empire of Pain: The Secret History of the Sackler Dynasty , by Patrick Radden Keefe 2.  The Good Nurse: A True Story of Medicine, Madness, and Murder , by Charles Graeber 3.  A Good Time to Be Born: How Science and Public Health Gave Children a Future , by Perri Klass 4.  The Price We Pay: What Broke American Health Care - and How to Fix It , by Marty Makary 5.  Searching for the Family Doctor: Primary Care on the Brink , by Timothy Hoff 6.  Sickening: How Big Pharma Broke American Health Care and How We Can Repair It , by John Abramson 7.  A Silent Fire: The Story of Inflammation, Diet, and Disease , by Shilpa Ravella 8.  The Song of the Cell: An Exploration of Medicine and the New Human , by Siddhartha Mukh

Decoding doctor-speak, redux

Eleven years ago, I wrote a post for my U.S. News Healthcare Headaches blog titled " Decoding doctor-speak: translations of common medical terms " that walked non-health professionals through explanations of common blood tests such as the complete blood count, basic metabolic panel, liver function tests, and low-density lipoprotein; and diagnoses such prediabetes and metabolic syndrome. It turned out to be an enduring hit; the cross-posted version on Common Sense Family Doctor has been viewed more than 11,000 times. But have I or physicians in general have gotten any better at keeping insider medical jargon out of our conversations with patients? A few weeks ago, JAMA Network Open published a cross-sectional study that assessed the general public's understanding of English phrases that have different meanings in a medical context (jargon) than they do in everyday life. Researchers surveyed 215 adult volunteers without a history of medical or nursing training who vis

The Latest on COVID-19, Immunity, and Thrombosis Risk

At ASH 2022, experts discuss how the virus breaches the immune system and how to recognize vaccine-related blood clots. MDedge News source https://www.medscape.com/viewarticle/986093?src=rss

California University Apologizes for Prisoner Experiments

Two dermatologists at the University of California, San Francisco, conducted the experiments on men at the California Medical Facility, a prison hospital. Associated Press source https://www.medscape.com/viewarticle/986096?src=rss

Optimal Surgery Timing After Chemo in Esophageal Cancer?

New data show that survival outcomes were best when surgery came 6–8 weeks after neoadjuvant chemotherapy. The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/986091?src=rss

Lawmakers Introduce Comprehensive Cancer Survivorship Act

The new legislation will address gaps in care that cancer survivors experience and will establish standards to reduce costs and improve the quality of care. Medscape Medical News source https://www.medscape.com/viewarticle/986089?src=rss

Children's Daily Screen Time Jumped 52% During Pandemic

Since the outset of the COVID-19 pandemic, persons aged 18 years and younger have increased their time on digital screens by more than 80 minutes per day. Medscape Medical News source https://www.medscape.com/viewarticle/986086?src=rss

DOJ Win Draws Attention to Battles Over Nurse Staffing Firms

An antitrust win involving a nurse staffing firm's bid to suppress wages signals the federal justice system's interest in addressing tactics used to suppress competition, perhaps leading to future crackdowns. Medscape Medical News source https://www.medscape.com/viewarticle/986085?src=rss

FDA Approves First-in-Class Drug for Follicular Lymphoma

The first-in-class bispecific antibody mosunetuzumab-axgb (Lunsumio) has been granted an accelerated approval for use in relapsed or refractory follicular lymphoma. FDA Approvals source https://www.medscape.com/viewarticle/986083?src=rss

Babies Inadvertently Exposed to Opioids + Tranquilizer: Report

A rise in the use of illegal opioids tainted with xylazine, an animal tranquilizer, is reaching drug users' children, according to a new case report from Delaware. Medscape Medical News source https://www.medscape.com/viewarticle/986054?src=rss

Coffee Intake in Severe HTN Tied to Higher CV Mortality

The potential adverse effects of caffeine in people with severe hypertension may outweigh the putative overall cardioprotective benefits of coffee intake, researchers propose. Medscape Medical News source https://www.medscape.com/viewarticle/986018?src=rss

Butyrate Improves BMI and Other Key Measures in Pediatric Obesity

In an Italian clinical trial of children with obesity, 6 months of butyrate supplementation was associated with a 10% average reduction in BMI and improved metabolic measures. Medscape Medical News source https://www.medscape.com/viewarticle/986039?src=rss

Is Glimepiride a Safer Sulfonylurea for Type 2 Diabetes?

Observational data show that certain types of sulfonylureas for the treatment of type 2 diabetes are associated with more cardiovascular events compared to other types, such as glimepiride. Medscape Medical News source https://www.medscape.com/viewarticle/986030?src=rss

Who Benefits From 5 Years of Extended Endocrine Therapy?

MammaPrint genomic testing suggests that only patients with low-risk, not ultra-low-risk or high-risk, breast cancer benefit from 5 years of extended endocrine therapy. Medscape Medical News source https://www.medscape.com/viewarticle/986024?src=rss

Has COVID-19 Impacted Mental Health Among Patients With Cancer?

Poverty, not the pandemic, appeared to have the greatest impact on psychological well-being among patients with cancer. The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/986023?src=rss

You May One Day Listen With Your Mouth

You could one day wear hearing aids in your mouth thanks to dental implant technology. Quick Take source https://www.medscape.com/viewarticle/986022?src=rss

FDA Approves Abaloparatide (Tymlos) for Osteoporosis in Men

The FDA has approved abaloparatide (Tymlos) for increasing bone density in men with osteoporosis at high risk for fracture. FDA Approvals source https://www.medscape.com/viewarticle/986014?src=rss

Europe Tackles Late HIV Head-on

Cases of late HIV might be averted if multi-prong strategies are implemented, including redefining the category for better monitoring. Medscape Medical News source https://www.medscape.com/viewarticle/985966?src=rss

Problematic Alcohol Use on the Rise Among Physicians?

Although rates of problematic alcohol use appear to be increasing among physicians, data on true prevalence and salient risk factors are lacking, investigators note. Medscape Medical News source https://www.medscape.com/viewarticle/985957?src=rss

Children and COVID: New-Case Counts Offer Dueling Narratives

The increase of almost 19,000 cases is the largest over a 2-week period since late July. MDedge News source https://www.medscape.com/viewarticle/985954?src=rss

Traveling by Public Transportation? CDC Says Wear a Mask

Government and medical officials have a familiar piece of advice for anyone taking public transportation this season. WebMD Health News source https://www.medscape.com/viewarticle/985949?src=rss

Dietary Interventions Can Support IBD Treatment

Certain diets may work better for different people and require a personalized approach. Medscape Medical News source https://www.medscape.com/viewarticle/985944?src=rss

Sarcopenia Risk Score Targets People With Type 2 Diabetes

The new risk score, which includes age, body mass index, and glycemia level, identifies people with type 2 diabetes who may benefit from intervention to preserve their muscle function. First Look source https://www.medscape.com/viewarticle/985891?src=rss

Article on Sexual Orientation and Psychiatric Disorders Retracted

A detailed thread was tweeted about how the review article “completely misrepresented” one of the studies. Retraction Watch source https://www.medscape.com/viewarticle/985881?src=rss

How to Get Your Healthcare Organization to Listen to Your Ideas

When you work for a healthcare organization it can feel like your ideas aren't valued. Here is some advice for getting them to listen. Medscape Medical News source https://www.medscape.com/viewarticle/985876?src=rss

Can Metformin Lower Need for Joint Replacement in Diabetes?

Patients with type 2 diabetes who were treated with metformin had a 30% reduction in risk for total knee and total hip replacement, compared with patients who did not receive the drug. Medscape Medical News source https://www.medscape.com/viewarticle/985875?src=rss

Contrast-Enhanced Mammography Improves Breast Cancer Surveillance

The findings support use of contrast-enhanced mammography for surveillance in breast cancer survivors. The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/985870?src=rss

Radium-223 May Add Small Benefit in Bone-Metastatic Breast Cancer

Adding radium-223 to estrogen therapy to target bone metastases may provide slight gain but comes with more adverse events. The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/985868?src=rss

Doctor Describes War Medicine Training in Ukraine

Anesthesiologist Raphaël Pitti, MD, relates his experiences in training Ukrainian physicians in emergency ultrasound. Medscape Medical News source https://www.medscape.com/viewarticle/985811?src=rss

Is There Hope in the Fight Against Aging?

A clinician summarizes recent advances in our understanding of the mechanisms underlying biological aging. Medscape Medical News source https://www.medscape.com/viewarticle/985809?src=rss

Vaccinating Pregnant Women Protects Infants Against Severe RSV

The vaccine RSVpreF had an almost 82% efficacy against severe RSV infection in infants from birth through the first 90 days of life, according to company data. Medscape Medical News source https://www.medscape.com/viewarticle/985810?src=rss

Smoking May Influence Fatal Prostate Cancer Risk

The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/985803?src=rss

Antibiotic Use Decreased, Resistance Stable in Germany

Despite favorable developments in the use of antibiotics, more than 35,000 people die every year in Europe from antibiotic-resistant infections. Medscape Medical News source https://www.medscape.com/viewarticle/985808?src=rss

AI vs Other Interventions for Colonoscopy: How Do They Compare?

While artificial intelligence (AI) improved adenoma detection rates, it did not improve the detection rates of all polyp types. Medscape Medical News source https://www.medscape.com/viewarticle/985799?src=rss

Post-op Chemo Has Limited Benefit in Some Esophageal Cancers

Patients with stage IIA and IIB esophageal squamous cell carcinoma with lymphovascular invasion but negative lymph nodes do not benefit. The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/985704?src=rss

Fitbit Figures: More Steps Per Day Cut Type 2 Diabetes Risk

Physical activity was associated with lower risk for type 2 diabetes, regardless of the intensity level, and even at amounts less than current guidelines recommend, based on 4 years of Fitbit data. Medscape Medical News source https://www.medscape.com/viewarticle/985703?src=rss

MRI-Targeted Biopsy Halves Prostate Cancer Overdiagnosis

Compared with systematic biopsy, MRI-directed targeted biopsy found fewer harmless tumors but did delay detection of some intermediate-risk tumors. Medscape Medical News source https://www.medscape.com/viewarticle/985702?src=rss

Docs Treating Other Doctors: What Can Go Wrong?

Some doctors enjoy treating their fellow physicians as patients while others find it intimidating. Poll respondents reveal some of the pros and cons of treating their peers. Medscape Medical News source https://www.medscape.com/viewarticle/985690?src=rss

Oncologists Overwhelmed; Cluster Headaches; and Liver Cancer Cost

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/985605?src=rss

Squeezed by Temp Nurse Costs, Hospital Groups Form Staffing Agencies

In an effort to manage the pandemic-related nursing shortage, more hospitals have formed in-house staffing teams. Kaiser Health News source https://www.medscape.com/viewarticle/985639?src=rss

J&J and Merck Ebola Vaccines Produce Lasting Antibodies in Children and Adults: Studies

Ebola vaccines developed by Johnson & Johnson and Merck produced virus-fighting antibodies and appear to be safe in children and adults, according to data from two studies published on Wednesday. Reuters Health Information source https://www.medscape.com/viewarticle/985600?src=rss

US Ready to Help China on COVID-19 Surge if Beijing Asks: White House

The United States is prepared to help China deal with a surge of COVID-19 infections if Beijing requests assistance, the White House said on Wednesday. Reuters Health Information source https://www.medscape.com/viewarticle/985596?src=rss

China's COVID Spike Not Due to Lifting of Restrictions: WHO Director

COVID-19 infections were exploding in China well before the government's decision to abandon its strict 'zero-COVID' policy, a World Health Organization director said on Wednesday. Reuters Health Information source https://www.medscape.com/viewarticle/985563?src=rss

States Challenge Biden to Lower Drug Prices

Colorado has joined Florida, New Hampshire, and New Mexico in seeking federal permission to import prescription drugs from Canada. Kaiser Health News source https://www.medscape.com/viewarticle/985637?src=rss

Liver Cancer Exacts High Financial Toll on Older Adults

The financial burden of hepatocellular carcinoma, the most common type of liver cancer, is high for Medicare beneficiaries in the first year after diagnosis. Medscape Medical News source https://www.medscape.com/viewarticle/985616?src=rss

Weight Loss Drugs; Cancer in the Middle East; and Doctor Jobs

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/985541?src=rss

Don't Overuse Mobile Devices to Calm Screaming Children: Study

While using mobile devices to soothe outbursts is fine sometimes, new research suggests that doing so too often could delay a child's ability to manage their emotions productively. WebMD Health News source https://www.medscape.com/viewarticle/985588?src=rss

A Hiking Accident Becomes a Helicopter Disaster

A camping trip goes from bad to bloody when a physician with a broken ankle suddenly must rescue his rescuer. Medscape Medical News source https://www.medscape.com/viewarticle/985576?src=rss

Mothers' Sleep Issues Promote Poor Outcomes for Infants

Sleep apnea and insomnia in pregnancy may offer insight into risk assessment for infants. Medscape Medical News source https://www.medscape.com/viewarticle/985570?src=rss

Low Risk of ALCL With Postmastectomy Implant Reconstruction

The finding comes from the first study of the risk of developing anaplastic large-cell lymphoma (ACLC) after implant reconstruction following a cancer-directed mastectomy. Medscape Medical News source https://www.medscape.com/viewarticle/985569?src=rss

Intermittent Fasting Can Lead to Type 2 Diabetes Remission

Intermittent fasting could be a paradigm shift in type 2 diabetes management, allowing patients to stop taking glucose-lowering medication, a small randomized trial in patients in China suggests. Medscape Medical News source https://www.medscape.com/viewarticle/985558?src=rss

Choosing Private Practice; Cancer and Psilocybin; and Memory Loss

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/985462?src=rss

Oral SERD Camizestrant Prolongs PFS vs Fulvestrant in Breast Cancer

"The results of SERENA-2 support further development of camizestrant in ER-positive breast cancer." MDedge News source https://www.medscape.com/viewarticle/985507?src=rss

Immune Disregulation May Drive Long-Term Postpartum Depression

PTSD, depression, and anxiety in mothers may persist 2-3 years after birth, a new study found, suggesting mothers should be screened for mental health for more than a year after birth. MDedge News source https://www.medscape.com/viewarticle/985502?src=rss

Do Younger Doctors Have Lower Patient Volumes?

A new study suggests that recently trained family physicians practice similarly to their predecessors and are not to blame for medical access challenges in Canada. Medscape Medical News source https://www.medscape.com/viewarticle/985488?src=rss

Alloantibody Data Exchange Would Save Lives, Reduce Costs

A central repository of data on alloantibodies could spare patients who require transfusions from potentially fatal complications such as delayed hemolytic transfusion reactions. Medscape Medical News source https://www.medscape.com/viewarticle/985487?src=rss

Adagrasib (Krazati) Approved for KRAS-Mutated NSCLC

It becomes the second KRAS-targeted therapy for use in patients with non–small cell lung cancer (NSCLC) whose tumors have this mutation. FDA Approvals source https://www.medscape.com/viewarticle/985480?src=rss

COVID Drugs Dwindle; Canada Needle Exchange; and New CMS Rule

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/985359?src=rss

Women Can Safely Interrupt Endocrine Tx to Pursue Pregnancy

Interrupting endocrine therapy may allow three quarters of women with hormone receptor positive breast cancer to achieve pregnancy, while having no impact on their short-term outcomes, new data suggest. Medscape Medical News source https://www.medscape.com/viewarticle/985423?src=rss

Canada's Prison Needle Exchange Program Has Limitations

Key challenges to broader participation in the program include confidentiality, the potential threat of punishment, and lack of knowledge about the program. Medscape Medical News source https://www.medscape.com/viewarticle/985416?src=rss

Psychosocial Stress Tied to Elevated Risk for Acute Stroke

The latest findings from the INTERSTROKE study show high stress at work and home significantly increases stroke risk. But feeling in control of work and home life cut that risk Medscape Medical News source https://www.medscape.com/viewarticle/985410?src=rss

MIPS Quality Scores Don't Reflect Quality of Care: Study

Despite substantial data-reporting requirements for physicians, the Medicare payment incentive program's measures don't say much about a doctor's quality, a new JAMA study finds. Medscape Medical News source https://www.medscape.com/viewarticle/985396?src=rss

Breast Conservation Safe Option in Multisite Breast Cancer

Eagerly awaited results show for the first time, from a prospective trial, that women with multiple breast cancer foci can safely undergo breast-conserving therapy, with low local recurrence rates. Medscape Medical News source https://www.medscape.com/viewarticle/985394?src=rss

Racism in Maternity Outcomes; Gaps in Cancer Care; Breaking Bad News in IVF

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/985285?src=rss

High-Dose MTX Does Not Reduce CNS Relapse in Pediatric ALL

The UKALL2011 study also showed that a shorter course of dexamethasone did not reduce toxicities, and that monthly pulses of vincristine/dexamethasone don't reduce bone marrow relapse. Medscape Medical News source https://www.medscape.com/viewarticle/985385?src=rss

'Astonishing' Results: Skip Salvage Chemo, Go Straight to HSCT

Investigators said they were astonished by the results they saw when patients with refractory acute myeloid leukemia went straight to an allogeneic stem cell transplant. Medscape Medical News source https://www.medscape.com/viewarticle/985384?src=rss

For Minorities With PE: Less Advanced Treatment, More Mortality

Non-White patients with pulmonary embolism (PE) were less likely to get advanced therapies, and Hispanics and Asians/Pacific Islanders, had higher death rates than Whites, new data show. MDedge News source https://www.medscape.com/viewarticle/985381?src=rss

Poorly Matched Stem Cell Transplants Linked to Ancestry

Non-European ancestry is a risk factor for receiving the 'most complex' bone marrow transplantations, and this factor is related to socioeconomic status, new results suggest. MDedge News source https://www.medscape.com/viewarticle/985380?src=rss

Worldwide Efforts Needed to Close Regional HSCT Utilization Gap

Although hematopoietic stem cell transplants (HSCT) offer a cure for acute myeloid leukemia, in some countries only 5% of patients are offered this option. Medscape Medical News source https://www.medscape.com/viewarticle/985333?src=rss

Behavioral Treatment Tied to Lower Medical, Pharmacy Costs

New research supports efforts to promote outpatient behavioral health treatment as part of a population health strategy to reduce overall medical spending. Medscape Medical News source https://www.medscape.com/viewarticle/985321?src=rss

Obesity Linked to Higher Risk for Adverse Events From Nivolumab

The risk for grade 3 and 4 immune-related adverse events, in particular, was only higher among women with obesity receiving nivolumab monotherapy. Medscape Medical News source https://www.medscape.com/viewarticle/985325?src=rss

More States to Consider Extending Postpartum Medicaid Coverage

Fifteen states haven't moved to extend Medicaid coverage for new moms beyond the minimum of 60 days after birth. Kaiser Health News source https://www.medscape.com/viewarticle/985315?src=rss

More Warnings of Substantial Rise in Type 2 Diabetes in Youth

The burden of early onset type 2 diabetes has increased among youth worldwide, mirroring findings already seen in the US and other high-income nations. Medscape Medical News source https://www.medscape.com/viewarticle/985314?src=rss

States Cracking Down Harder on Docs Who Sexually Abuse Patients

States are tackling sexual misconduct after criticism of medical board leniency. Under a new California law, doctors won't get a second chance at licensure if they sexually exploit patients. Medscape Medical News source https://www.medscape.com/viewarticle/985306?src=rss

People With Diabetes Choose Agents that Best Control Glucose

People with type 2 diabetes who tried agents from three different classes of glucose-lowering drugs usually found one they liked most. It was also often their safest and most effective option. Medscape Medical News source https://www.medscape.com/viewarticle/985313?src=rss

Black Women and Cancer; Psychiatric NPs; and Buddhist Teachings

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/985230?src=rss

CDC: Mpox Vaccine Is Effective Regardless of Administration Route

Since the peak of the outbreak in July, mpox cases in the United States have fallen 95%. Medscape Medical News source https://www.medscape.com/viewarticle/985272?src=rss

Tiny, Menacing Microclots May Explain Long COVID’s Symptoms

Some long COVID researchers have suspected smaller, less obvious blood clots may be causing many of the puzzling symptoms reported by patients who have lasting effects of the virus. WebMD Health News source https://www.medscape.com/viewarticle/985271?src=rss

NPs Can Offset Psychiatry Shortage, Tackle Mental Health Crisis

Psychiatric mental health nurse practitioners are in high demand to meet the growing needs of those seeking mental health services at a time when psychiatrists aren’t as available or affordable. Medscape Medical News source https://www.medscape.com/viewarticle/985259?src=rss

Do Buddhist Teachings Protect Against Depression?

Most practitioners have heard of mindfulness, which is derived from Buddhist practice. This study looks at the potential benefits of observing five key Buddhist precepts in protecting against depression. Medscape Medical News source https://www.medscape.com/viewarticle/985256?src=rss

Around 5.5 Million People Have Signed Up for 2023 Obamacare Plans

Nearly 5.5 million Americans so far have signed up for health insurance for next year through the Affordable Care Act's marketplace, an 18% increase over the same period last year, according to data released by the U.S. Department of Health and Human Services on Wednesday. Reuters Health Information source https://www.medscape.com/viewarticle/985193?src=rss

Health System Jobs; Psychedelic Laws; and Pricey Paxlovid

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/985151?src=rss

Don’t Lift Weights – Lower Them Instead

New research suggests you can focus on lowering the load, and cheat on the lifting part, without sacrificing results. WebMD Health News source https://www.medscape.com/viewarticle/985188?src=rss

Seeds of Change to Counter Dijon Mustard Shortage

French Dijon mustard producers hope to soon be restocking store shelves after shifting their seed growing to France’s Burgundy region following an ongoing shortage due to problems with pests, drought, and supply chain issues. Quick Take source https://www.medscape.com/viewarticle/985180?src=rss

SARS-CoV-2 Seroprevalence Grew Rapidly in Canada

Seroprevalence surveys found that fewer than half of people older than 60 years had been exposed to the virus. The researchers suggest that this age group be prioritized for vaccination. Medscape Medical News source https://www.medscape.com/viewarticle/985170?src=rss

High Rates of Inappropriate PPI Use in Hospitalized Patients

More than two fifths of patients discharged with a proton pump inhibitor prescription may have been given it inappropriately, say Israeli researchers who call for action to improve the problem. Medscape Medical News source https://www.medscape.com/viewarticle/985171?src=rss

Pfizer Partners With Clear Creek Bio to Develop Oral COVID-19 Drug

Pfizer and Clear Creek Bio on Tuesday announced a collaboration to identify a potential drug candidate and develop a new class of oral treatment against COVID-19, as Pfizer seeks to expand its anti-infective pipeline. Reuters Health Information source https://www.medscape.com/viewarticle/985069?src=rss

US Backs Delay to Decision on COVID Patent Waiver Extension

The United States on Tuesday urged delaying a decision on whether to waive patent protection for COVID-19 treatments and tests, as demanded by many developing countries, a move branded 'pathetic' by a leading campaign group. Reuters Health Information source https://www.medscape.com/viewarticle/985066?src=rss

24% of Adults With Hypertension Have Subclinical Hypothyroidism

The prevalence of subclinical hypothyroidism among adults with hypertension was 24%, compared with 17% among normotensive adults in a random sample of 2818 adults living in a single Chinese province. First Look source https://www.medscape.com/viewarticle/985169?src=rss

Prenatal Tests; Meth Heart Failure; and Cardio and PTSD

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/985029?src=rss

Employers Use Patient Assistance Programs to Offset Their Costs

Some insurers and employers are tapping into assistance programs meant for individual patients. The concern: Some costly drugs could be harder for patients to access. Kaiser Health News source https://www.medscape.com/viewarticle/985102?src=rss

'Meth' Heart Failure on the Rise, Often More Severe

Researchers urge increased awareness of heart failure due to illicit use of methamphetamine, which may be more severe than non-MethHF. Medscape Medical News source https://www.medscape.com/viewarticle/985080?src=rss

Which Patients Are at Risk for Depression During Pandemic?

Patients with a history of depression were four times more likely to be depressed during the COVID-19 pandemic than those without. Medscape Medical News source https://www.medscape.com/viewarticle/985077?src=rss

Flu Season Raged Over Thanksgiving

The flu virus made the most of the Thanksgiving holiday by reaching the highest level of national activity seen since the 2017-18 influenza season, according to the CDC. WebMD Health News source https://www.medscape.com/viewarticle/985071?src=rss

Diabetes Boosts Postoperative Opioid Use

People with diabetes, especially those with type 1 diabetes, were significantly more likely to have prolonged opioid use following surgery compared to people without diabetes who underwent surgery. First Look source https://www.medscape.com/viewarticle/985068?src=rss

Alcohol-Cancer Link; Mpox and Women; Hearing Aids and Dementia

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/984959?src=rss

Study Comparing Surgical and N95 Masks Sparks Concern

Experts have identified shortcomings in a study that suggests that surgical masks are not inferior to N95 masks for protecting healthcare workers against COVID-19. Medscape Medical News source https://www.medscape.com/viewarticle/984992?src=rss

Top 5 Breast Cancer Articles From November

Medscape Medical News put together a list of the most notable breast cancer stories published last month. Medscape Medical News source https://www.medscape.com/viewarticle/984980?src=rss

Not All Plant-Based Diets Equal for CRC Risk Reduction

Megan Brooks Medscape Medical News source https://www.medscape.com/viewarticle/984981?src=rss

'Game Changer': Thyroid Cancer Recurrence No Higher With Lobectomy

Patients with intermediate-risk papillary thyroid cancer who undergo lobectomy versus total thyroidectomy as the surgical approach show no significant differences in recurrence-free survival. Medscape Medical News source https://www.medscape.com/viewarticle/984979?src=rss

Amgen Says Experimental Obesity Drug Has Promising Durability

Amgen's experimental obesity drug demonstrated promising durability trends in an early trial, paving the way for a larger mid-stage study early next year, company officials said ahead of a data presentation on Saturday. Reuters Health Information source https://www.medscape.com/viewarticle/984965?src=rss

Pfizer to Invest More Than $2.5 Billion to Expand European Manufacturing

Pfizer is investing more than $2.5 billion at its drug making plants in Belgium and Ireland, gearing up to launch new products it hopes can replace lost revenue as patents expire and COVID-19 vaccine sales decline. Reuters Health Information source https://www.medscape.com/viewarticle/984908?src=rss

Pregnancy Outcomes on Long-Acting Antiretroviral

A study helps to establish a runway for clinical trials of long-acting cabotegravir and rilpivirine in pregnant women. Medscape Medical News source https://www.medscape.com/viewarticle/984978?src=rss

Women Surgeons; Consent Talk; and Women on Advisory Boards

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/984893?src=rss

New AAFP practice guideline sets blood pressure targets for adults with hypertension

From 1977 to 2003, seven Joint National Committees (JNC), sponsored by the National Heart, Lung, and Blood Institute (NHLBI), produced consensus multi-specialty guidelines on the diagnosis and management of hypertension. In 2013, well into the development of JNC8, the NHLBI abruptly turned the process over to the American College of Cardiology/American Heart Association (ACC/AHA). The JNC8 committee independently published an evidence-based guideline in JAMA that raised the blood pressure treatment threshold in most older adults from 140/90 to 150/90 mm Hg. Concerned about conflicts of interest and other deviations from Institute of Medicine-recommended practices for developing trustworthy guidelines , primary care groups, including the American Academy of Family Physicians (AAFP), declined to participate in the ACC/AHA guideline panel. And the longstanding edifice of hypertension guidelines fractured. In 2017, the ACC/AHA released its clinical practice guideline , which most notab

Cancer Research Falls Short on Data and Code Sharing

Data were made available in only 16% of oncology articles randomly selected for analysis, and only 1% complied with best practices for data and code sharing. Medscape Medical News source https://www.medscape.com/viewarticle/984920?src=rss

NPs React: Addressing Burnout and Depression

A Medscape report focused on high levels of burnout affecting nurse practitioners, a problem that only worsened with the COVID-19 pandemic. Here's what your colleagues are saying. Medscape Medical News source https://www.medscape.com/viewarticle/984917?src=rss

How Blunt Is Too Blunt for Informed Consent?

One of the toughest jobs physicians have is getting informed consent. Since patients must be aware of the risks and rewards of any treatment, just how blunt is too blunt when you explain? Medscape Medical News source https://www.medscape.com/viewarticle/984914?src=rss

Single Chest X-Ray Could Predict 10-Year CVD Risk

The standard risk calculator requires nine variables, and not all of them are always available in the EHR. The proposed CXR model has performed similarly to the standard model. Medscape Medical News source https://www.medscape.com/viewarticle/984910?src=rss

FDA Approves Olutasidenib (Rezlidhia) for Certain Patients With AML

The drug has been approved for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with a susceptible IDH1 mutation as detected by an FDA-approved test. FDA Approvals source https://www.medscape.com/viewarticle/984907?src=rss

CDC to Test for Polio; FDA Approvals; and Meals and Mortality

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/984798?src=rss

Strong Two-Way Link Between Epilepsy and Depression

The increased risk of depression following epilepsy, and vice versa, is sustained over a much longer period than previously shown. Medscape Medical News source https://www.medscape.com/viewarticle/984872?src=rss

Odd Twist in Phase 3 Alzheimer's Trial for Novel Tau Inhibitor

Although the novel tau aggregation inhibitor hydromethylthionine mesylate did not reach its coprimary endpoints, investigators insist there's more to the story ― especially with the control agent used. Medscape Medical News source https://www.medscape.com/viewarticle/984863?src=rss

HS Treated in EDs Not Followed Up in Derm Clinics, Study Finds

The study "highlights potential areas of action to improve care for patients with HS,” the authors concluded. MDedge News source https://www.medscape.com/viewarticle/984859?src=rss

New Model Aims to Aid Monkeypox Vaccine Distribution

A new model has been developed to guide public health policy makers on the most efficient way to distribute a limited supply of monkeypox vaccines to those who need it the most. Medscape Medical News source https://www.medscape.com/viewarticle/984841?src=rss

Steam Cleaning Dishes Is More Effective, Environmentally Friendly

Using superheated steam in dishwashers could provide a more effective, environmentally friendly solution to cleaning dishes. Quick Take source https://www.medscape.com/viewarticle/984800?src=rss

Ozempic Shortage; New MS Framework; and AI in Drug Trials

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/984741?src=rss