All cancer screening tests have diminishing benefits and increasing harms as people age. An article in the December 2025 issue of American Family Physician reviewed considerations for discontinuing cancer screenings in older adults. For cervical cancer , the authors observed that 21% of new cases and 38% of deaths occur after 65 years, the usual age to stop screening . Notably, this stopping age applies only to patients without conditions that put them at high risk of cervical cancer (eg, HIV infection) who have had adequate prior screening, defined as “ three consecutive negative cytology results or two consecutive negative cotesting results within 10 years .” In a recently published guideline , the American Cancer Society (ACS) clarified that the last negative test before exiting cervical cancer screening should occur “at an age no younger than 65 years,” with primary human papillomavirus (HPV) testing at 60 and 65 years of age being preferred. The ACS reiterated its previous reco...