Most of the major cancer types have a single recommended screening test. For breast cancer, mammography . For cervical cancer, cytology and/or human papillomavirus testing . For lung cancer, low-dose computed tomography (CT). Colorectal cancer is unique in that physicians and patients have a menu of acceptable screening options , ranging from various stool-based tests to CT colonography, colonoscopy, and most recently, a blood test for circulating tumor DNA. Guidelines recommend shared decision making with average-risk adults aged 45 to 75 years to select a colorectal cancer screening strategy that aligns with patients’ preferences and values. A recent scoping review of 28 studies in the United States and Canada explored factors that play important roles in these conversations. Researchers identified 4 domains that influence patients’ decision making: test attributes (accuracy, cost, convenience, and complications); recommendations from their personal physician; fear, discomfort a...