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Showing posts from November, 2025

‘Wide-Awake’ Anesthesia Effective for Carpal Tunnel

‘Wide-awake’ local anesthesia no tourniquet is noninferior to ultrasound-guided axillary block in patients undergoing carpal tunnel surgery, according to a new study. Medscape Medical News source https://www.medscape.com/viewarticle/local-anesthesia-no-tourniquet-matches-ultrasound-guided-2025a1000wfz?src=rss

PAHO: Americas Lose Measles-Free Status as Cases Surge

The region of the Americas loses measles elimination as outbreaks surge in Canada, Mexico, and the US, forcing urgent calls for restored coverage, surveillance, and rapid response. Medscape News Europe source https://www.medscape.com/viewarticle/paho-americas-lose-measles-free-status-cases-surge-2025a1000wfw?src=rss

Pulse Steroids Plus MMF Benefit Juvenile Dermatomyositis

IVMP plus mycophenolate mofetil as first-line therapy produced a high remission rate with sustained muscle and skin improvements in a study of children with dermatomyositis. Medscape Medical News source https://www.medscape.com/viewarticle/juvenile-dermatomyositis-remission-rates-high-intermittent-2025a1000wbc?src=rss

Can Anticoagulants Cut Stroke Risk in Seniors With AF?

Initiation of anticoagulants is not linked to a reduced risk for ischemic stroke in older patients with atrial fibrillation, a retrospective analysis of Medicare beneficiaries shows. Medscape Medical News source https://www.medscape.com/viewarticle/can-anticoagulants-cut-stroke-risk-seniors-atrial-2025a1000wbp?src=rss

Cognition Improved With Some Drugs for Depression

Antidepressant choice or strategy may not alter overall cognition in older adults with treatment-resistant depression, but some drugs may modestly improve inhibitory control. Medscape Medical News source https://www.medscape.com/viewarticle/cognition-improved-some-drugs-depression-2025a1000wbk?src=rss

Phone Use at Night Signals Next-Day Suicidal Behavior Risk

Late-night use of smartphones signals an elevated risk for suicidal ideation and planning the next day in adults at a high risk for suicide, while middle-of-the-night active engagement appears protective. Medscape Medical News source https://www.medscape.com/viewarticle/phone-use-night-signals-next-day-suicidal-behaviors-high-2025a1000w63?src=rss

GLP-1 RAs Effective for Weight Loss in T1D and Obesity

Tirzepatide, semaglutide, and liraglutide lead to weight loss in adults with obesity and T1D over 1 year; the greatest weight loss and a modest decrease in A1c levels are seen with tirzepatide. Medscape Medical News source https://www.medscape.com/viewarticle/glp-1-receptor-agonists-effective-weight-loss-type-1-2025a1000w65?src=rss

Polypill Shows Promise for Heart Failure

A heart failure polypill was not only associated with better adherence to guideline-directed medicines but also better outcomes at 6 months. Medscape Medical News source https://www.medscape.com/viewarticle/polypill-improves-cardiac-function-clinical-outcomes-hfref-2025a1000w0r?src=rss

Sleep Disorders Common in RA, Many Tied to Disease Activity

Sleep disorders are common in patients with rheumatoid arthritis, and many of them are significantly tied to greater clinical disease activity, a study finds. Medscape Medical News source https://www.medscape.com/viewarticle/sleep-disorders-common-ra-many-tied-disease-activity-2025a1000vue?src=rss

Estetrol Improves Vasomotor Symptoms With No BP Effects

The findings of two RCTs suggest estetrol has promise as an additional estrogen formulation option for postmenopausal women. Medscape Medical News source https://www.medscape.com/viewarticle/estetrol-improves-vasomotor-symptoms-menopausal-women-no-2025a1000vua?src=rss

Birch Rust Spores May Trigger Allergic Airway Symptoms

Birch rust spores may have a positive correlation with allergic airway symptoms in autumn, new research finds. Medscape Medical News source https://www.medscape.com/viewarticle/birch-rust-spores-may-trigger-allergic-airway-symptoms-2025a1000vn4?src=rss

Paying People to Take Hypertension Meds Only Goes So Far

A lottery with cash prizes got people to take their antihypertensive medications, but improved adherence didn’t translate to better blood pressure. Medscape Medical News source https://www.medscape.com/viewarticle/paying-people-take-hypertension-meds-only-goes-so-far-better-2025a1000vmx?src=rss

Over Half Regain Weight After Stopping GLP-1s

The largest real-world study to date of GLP-1 discontinuation finds over half regain weight within a year. Medscape Medical News source https://www.medscape.com/viewarticle/over-half-regain-weight-after-stopping-glp-1s-2025a1000vmt?src=rss

Healthy Food Delivery Boosts Quality of Life in HF

A pilot program that arranges delivery of healthy food to heart failure patients after hospital discharge shows promise for improving their quality of life, if not clinical outcomes. Medscape Medical News source https://www.medscape.com/viewarticle/healthy-food-delivery-boosts-quality-life-heart-failure-2025a1000vhh?src=rss

Bone Drug Fails to Stop Muscle Loss Post-Bariatric Surgery

Prophylactic treatment with zoledronic acid before bariatric surgery fails to prevent muscle loss, preserve strength, or improve physical function 12 months after the procedure. Medscape Medical News source https://www.medscape.com/viewarticle/bone-drug-fails-stop-muscle-loss-post-bariatric-surgery-2025a1000vh6?src=rss

LBCL: Do Genes Shape CAR T Outcomes?

New research suggests that DNA variants help predict toxicity and response in CAR T-cell therapy for large B-cell lymphoma. Medscape Medical News source https://www.medscape.com/viewarticle/lbcl-do-genes-shape-car-t-outcomes-2025a1000vb0?src=rss

Country Doctor: Shining a Powerful Lens on Rural Medicine

In Country Doctor, filmgoers get a firsthand look at the crisis facing doctors and the underfunded hospitals they’re working in. Medscape Medical News source https://www.medscape.com/viewarticle/country-doctor-shining-powerful-lens-rural-medicine-2025a1000van?src=rss

Perimenopausal Symptoms Linked to Lower Work Productivity

Researchers estimate that the average woman with perimenopausal symptoms loses about $6000 in productivity per year, adding up to roughly $49 billion across the US workforce. Medscape Medical News source https://www.medscape.com/viewarticle/perimenopausal-symptoms-linked-decline-work-productivity-2025a1000vap?src=rss

A Pharmacist’s Perspective on GLP-1s and Patient Access

Pharmacists are well-suited to help guide patients starting or continuing weight-loss drugs. Medscape Medical News source https://www.medscape.com/viewarticle/intersecting-crisis-pharmacists-perspective-glp-1s-patient-2025a1000v6t?src=rss

BLVR Candidates Tend Toward Heterogeneity

Identifying emphysema distribution patterns may inform trials and clinical decisions. Medscape Medical News source https://www.medscape.com/viewarticle/blvr-candidates-tend-toward-heterogeneity-2025a1000v6i?src=rss

Asthma Patients Experience Storm Surges

Emergency department data show impact of weather on vulnerable individuals. Medscape Medical News source https://www.medscape.com/viewarticle/asthma-patients-experience-storm-surges-2025a1000v0c?src=rss

Hispanic Patients Have Limited Access to Psoriasis Drugs

Hispanic adults with psoriasis receive biologics far less often than non-Hispanic White adults, despite having more prescriptions and more dermatologist visits. Medscape Medical News source https://www.medscape.com/viewarticle/hispanic-patients-psoriasis-receive-fewer-biologic-2025a1000v0a?src=rss

First Oral PCSK9 Inhibitor Rivals Injectables

Medscape Medical News source https://www.medscape.com/viewarticle/oral-pcsk9-inhibitor-provides-ldl-reductions-comparable-2025a1000v03?src=rss

Gene Therapy Shows Lipid Improvement but Raises Flags

A CRISPR-based gene therapy showed improvement in lipids in difficult-to-treat patients, but one study raised flags after a death last month in a trial of an unrelated gene therapy. Medscape Medical News source https://www.medscape.com/viewarticle/gene-therapy-shows-lipid-improvement-raises-flags-2025a1000uzw?src=rss

Expert Shares PsA Screening Tips for People With Psoriasis

The National Psoriasis Foundation recommends that patients with psoriasis be screened for PsA every 6 months. Medscape Medical News source https://www.medscape.com/viewarticle/expert-shares-psa-screening-tips-people-psoriasis-2025a1000uzs?src=rss

PCSK9 Inhibitor Found Effective for Primary Prevention

When added to optimized oral anti-lipid therapy, a PCSK9 blocker provided an additional 25% risk reduction in a first cardiovascular event, new data show. Medscape Medical News source https://www.medscape.com/viewarticle/global-trial-pcsk9-inhibitor-provides-major-protection-2025a1000uzp?src=rss

App Helps Smartwatch ID Structural Heart Disease

An AI-powered app can turn a smartwatch into a predictor of structural heart disease, a new study finds. Medscape Medical News source https://www.medscape.com/viewarticle/app-turns-smartwatch-detector-structural-heart-disease-2025a1000uzc?src=rss

Flood preparation, prevention, and an epidemic of short-term thinking

On July 4th, a flash flood in Kerr County, Texas killed 27 young girls and counselors at Camp Mystic , a Christian girls' summer camp whose staff alumni included former first lady Laura Bush. The campers and more than one hundred other local residents who also perished in the flood reacted too late, or not at all, to the National Weather Service's flash flood warning and emergency text alerts issued at 1:14 and 4:30 A.M., respectively. According to  an article in the New Yorker , "many people simply ignored the warnings, or had their phones silenced or turned off." The article mentioned that after a flood in 2015 that killed 13 people, Kerr County officials decided against installing a $1 million siren system that would have warned upriver towns when a flood was coming. In Vermont, which also experienced devastating flash floods in 2023 and 2024, the political response was different. In order to reduce the risk of recurrent floods, legislators passed a Flood Safety A...

Navigating the Skin-Related Variants of Lupus

‘A higher-titer ANA raises the suspicion that something more systemic may be going on,’ said Amanda Mixon, PA-C. Medscape Medical News source https://www.medscape.com/viewarticle/navigating-skin-related-variants-lupus-2025a1000uz8?src=rss

Artificial Light at Night May Raise CVD Risk

Increased exposure to artificial light at night is linked to higher stress-related activity in the brain, more inflammation in the arteries, and an increased risk for heart disease. Medscape Medical News source https://www.medscape.com/viewarticle/artificial-light-night-may-raise-cvd-risk-2025a1000uz6?src=rss

The ‘Medical Freedom’ Movement Finds Its Base Camp

MAGA and MAHA are happily married in Florida, and nowhere more at home than in Sarasota County. KFF Health News source https://www.medscape.com/s/viewarticle/hollow-florida-medical-freedom-movement-finds-its-base-camp-2025a1000us0?src=rss

Myasthenia Gravis Med Tied to Major Reduction in Steroid Use

18-month data show patients with generalized myasthenia gravis taking efgartigimod were able to reduce glucocorticoids to low levels or discontinue them. Medscape Medical News source https://www.medscape.com/viewarticle/myasthenia-gravis-med-tied-major-reduction-steroid-use-2025a1000us3?src=rss

GPs Urged to Lead ADHD Reform in the NHS

An independent taskforce has warned that ADHD care in England is failing patients and called for urgent system-wide reform to cut waiting times. Medscape News UK source https://www.medscape.com/viewarticle/gps-urged-lead-adhd-reform-nhs-2025a1000upp?src=rss

GLP-1 Weight Loss Post-Menopause Better With Hormone Therapy

Hormone therapy is indicated for vasomotor symptoms, not weight loss, suggesting the need to better understand why the differences exist. Medscape Medical News source https://www.medscape.com/viewarticle/glp-1-weight-loss-postmenopausal-women-greater-hormone-2025a1000ukf?src=rss

Spain Breaks Health Barriers With New Guinness World Records

The 2026 edition of Guinness World Records includes new health achievements from Spain. Medscape News Europe source https://www.medscape.com/viewarticle/spain-breaks-health-barriers-new-guinness-world-records-2025a1000ukc?src=rss

AML Treatment: Study Questions Age Cutoffs

A cross-continental study suggests that in the treatment of acute myeloid leukemia, age impacts survival, independent of genetic risk groups. Medscape Medical News source https://www.medscape.com/viewarticle/aml-treatment-study-questions-age-cutoffs-2025a1000uex?src=rss

Tofacitinib Combats Muscle Wasting in Rheumatoid Arthritis

Treating rheumatoid arthritis with tofacitinib for 6 months is linked to an increase in lower limb muscle volume, especially in the thigh, and a rise in serum creatinine levels. Medscape Medical News source https://www.medscape.com/viewarticle/tofacitinib-combats-muscle-wasting-rheumatoid-arthritis-2025a1000uer?src=rss

5 Hacks to Survive Night Shifts

Just 2- to 3-minute “microbreaks” each hour can noticeably improve cognitive performance and concentration during long night shifts. Medscape News Europe source https://www.medscape.com/viewarticle/5-hacks-survive-night-shifts-2025a1000ueg?src=rss

Dose Adjustment May Improve Safety After Immunotherapy Gaps

Down-titrating vial concentrations when restarting subcutaneous allergen immunotherapy after treatment gaps may help lower the risk for severe systemic reactions. Medscape Medical News source https://www.medscape.com/viewarticle/dose-adjustment-after-gaps-subcutaneous-allergen-2025a1000u91?src=rss

Does Anesthesia Type Affect Teen Recovery From ACL Surgery?

Regional anesthesia does not negatively affect functional recovery in adolescents after anterior cruciate ligament reconstruction surgery, with better outcomes by 6 months, a recent study shows. Medscape Medical News source https://www.medscape.com/viewarticle/do-anesthesia-choices-affect-recovery-adolescents-after-2025a1000u8p?src=rss

Flu Antiviral Prescriptions for US Kids Plunge During COVID

During the COVID pandemic, the rate of antiviral prescriptions in US emergency departments for children at a high risk for severe influenza fell by more than half. Medscape Medical News source https://www.medscape.com/viewarticle/flu-antiviral-prescriptions-us-kids-plunge-during-covid-2025a1000u8j?src=rss

Insurance, Race Main Barriers to Planned Egg Freezing

Black individuals were less likely than White individuals to proceed after a cryopreservation consultation. Medscape Medical News source https://www.medscape.com/viewarticle/insurance-race-main-barriers-planned-egg-freezing-2025a1000u2o?src=rss

Brensocatib’s Benefits Extend to Lung Structure

The first-in-class drug for bronchiectasis shows promise beyond reduced exacerbations and improved lung function. Medscape Medical News source https://www.medscape.com/viewarticle/brensocatibs-benefits-extend-lung-structure-2025a1000u2f?src=rss