Sharon Smith

The MUC-1 vaccine, when added to standard neoadjuvant systemic therapy, led to significant improvements in distant relapse-free survival & overall survival rates in BC patients. MDedge News source https://www.medscape.com/s/viewarticle/muc-1-vaccine-shows-notable-overall-survival-rates-bc-2024a1000c51?src=rss

Research shows elite athletes experience pain differently than everyday people. Here’s why, and how we can learn to deal with adversity and chronic pain every day. WebMD Health News source https://www.medscape.com/s/viewarticle/what-olympians-can-teach-rest-us-about-pain-2024a1000c4y?src=rss

Eliminating sick notes, adding AI aides, and other steps may cut down on the 18.5 million annual hours spent on "unnecessary" paperwork. Medscape Medical News source https://www.medscape.com/viewarticle/canadian-doctors-seek-reduce-administrative-burden-2024a1000c4x?src=rss

Academic pediatric practices have the highest Medicaid acceptance rate. Medscape Medical News source https://www.medscape.com/viewarticle/medicaid-acceptance-among-pediatric-dermatologists-varies-2024a1000c4w?src=rss

Second-generation basal insulins improved the glycemic parameters in patients with type 2 diabetes when added to or used as a substitute for GLP-1 therapy. Medscape Medical News source https://www.medscape.com/viewarticle/second-generation-basal-insulins-benefit-add-or-substitute-2024a1000c2m?src=rss

Several medical associations issued advanced imaging recommendations to improve pediatric emergency department care and reduce risks, such as radiation exposure and false-positives results. Medscape Medical News source https://www.medscape.com/viewarticle/balancing-advanced-imaging-risks-and-benefits-pediatric-2024a1000c2d?src=rss

Despite being highly processed, plant-based meat alternatives have a better cardioprotective profile than animal meat does, a new review suggested. Medscape Medical News source https://www.medscape.com/viewarticle/plant-based-meat-alternatives-may-be-better-heart-2024a1000c2b?src=rss

Marstacimab shows long-term safety and efficacy in preventing bleeding events in patients with hemophilia A and B without inhibitors, potentially expanding treatment options. MDedge News source https://www.medscape.com/s/viewarticle/hemophilia-marstacimab-sustains-long-term-bleeding-decrease-2024a1000c2a?src=rss

Sex-related but not thyroid-related hormones were independently associated with the risk for metabolic dysfunction–associated fatty liver disease in men with T2D. Medscape Medical News source https://www.medscape.com/viewarticle/sex-hormones-linked-fatty-liver-men-t2d-2024a1000bzh?src=rss

Thirty-three percent of nurses quit their jobs within 2 years of graduating. What’s causing a mass exodus from the nursing profession — and what can be done to fix it? Medscape Medical News source https://www.medscape.com/viewarticle/why-nurses-quit-2024a1000bza?src=rss

Cancer centers in the US are still reporting shortages of critical systemic therapies, but last year's carboplatin and cisplatin shortages have largely resolved. Medscape Medical News source https://www.medscape.com/viewarticle/cancer-drug-shortages-continue-us-survey-finds-2024a1000bz8?src=rss

An individual's maternal vs paternal family history of memory impairment may have a different effect on the risk for brain amyloid accumulation. Medscape Medical News source https://www.medscape.com/viewarticle/heritable-alzheimers-risk-not-just-maternal-2024a1000bz7?src=rss

Researchers are delving deeper into the complicated relationships between migraine and cardiovascular and cerebrovascular outcomes. Medscape Medical News source https://www.medscape.com/viewarticle/new-insight-cvd-stroke-risk-migraine-2024a1000buu?src=rss

At a recent conference, experts discussed the future of CAR-T therapy and its value as a first-line treatment for large B-cell lymphoma. Medscape Medical News source https://www.medscape.com/viewarticle/dual-car-t-therapies-are-becoming-more-established-2024a1000bur?src=rss

The recommendations highlighted the use of immunosuppressive agents and antifibrotics to treat skin fibrosis and lung fibrosis, as well as changes to upfront treatment of pulmonary hypertension. Medscape Medical News source https://www.medscape.com/viewarticle/updated-systemic-sclerosis-recommendations-eular-use-2024a1000bup?src=rss

Patients receiving sonelokimab experienced higher treatment response in ACR20, ACR50, and PASI90 than those in the placebo group. Medscape Medical News source https://www.medscape.com/viewarticle/sonelokimab-yields-significant-improvements-active-psa-early-2024a1000buo?src=rss

In a recent study, diabetes and chronic respiratory diseases were the most frequently represented comorbidities in patients with polypharmacy. Medscape Medical News source https://www.medscape.com/viewarticle/still-too-many-inappropriate-prescriptions-among-elderly-2024a1000bqg?src=rss

Just one third of outpatient community mental health treatment facilities in 20 states report they offer medication for opioid use disorder, new research showed. Medscape Medical News source https://www.medscape.com/viewarticle/medical-treatment-opioid-use-disorders-falls-short-2024a1000bqf?src=rss

Levels of neurofilament light chain may be a biomarker of chemotherapy-induced peripheral neurotoxicity, new research suggests. Medscape Medical News source https://www.medscape.com/viewarticle/neurofilament-light-chain-detects-early-chemotherapy-related-2024a1000bqe?src=rss

The microbiologist's discovery helped revolutionize the prevention and treatment of cardiovascular diseases. Medscape Medical News source https://www.medscape.com/viewarticle/akira-endo-father-statins-dies-2024a1000bmg?src=rss

At the same time the Medicare population is growing, the number of family practice (FP) physicians and the number of procedures they perform are decreasing. MDedge News source https://www.medscape.com/s/viewarticle/number-fps-procedures-they-perform-dropping-2024a1000bmf?src=rss

Use of premeal Afrezza insulin plus long-acting degludec insulin was non-inferior to automated insulin delivery or multiple daily-injection regimens, but it isn't for everyone. Medscape Medical News source https://www.medscape.com/viewarticle/inhaled-insulin-plus-degludec-option-type-1-diabetes-2024a1000bmb?src=rss

Two new analyses of the SELECT trial show that the GLP-1 receptor agonist improves cardiovascular health and reduces or normalizes glycemic levels irrespective of baseline A1c. Medscape Medical News source https://www.medscape.com/viewarticle/select-semaglutide-reduces-cv-events-and-diabetes-risk-2024a1000bma?src=rss

Even with a mean delay of 2.7 years, patients who put off statin therapy show a significantly increased long-term risk for heart attack and ischemic stroke. Medscape Medical News source https://www.medscape.com/viewarticle/delaying-statin-therapy-diabetes-increases-cv-risk-2024a1000bm9?src=rss

Old lipid drug holds new promise for reducing the need for retinal laser or intravitreal injections. Medscape Medical News source https://www.medscape.com/viewarticle/trial-fenofibrate-slows-diabetic-retinopathy-progression-2024a1000bm8?src=rss

Researchers have reported positive findings from small studies demonstrating how increasingly popular CGM devices can be integrated into hospital care of people with diabetes. Medscape Medical News source https://www.medscape.com/viewarticle/continuous-glucose-monitoring-can-aid-hospital-patients-2024a1000bm5?src=rss

An observational study of patients treated at the Cleveland Clinic suggests cardiovascular benefits of weight loss via bariatric surgery for people with obstructive sleep apnea and obesity. Medscape Medical News source https://www.medscape.com/viewarticle/bariatric-surgery-lowers-risk-mace-patients-moderate-severe-2024a1000bm2?src=rss

The dual GIP/GLP-1 agonist is the first drug to show benefit in patients with obstructive sleep apnea. Medscape Medical News source https://www.medscape.com/viewarticle/tirzepatide-significantly-reduces-sleep-disruptions-2024a1000bm1?src=rss

Hydroxychloroquine levels are linked to maternal flares in SLE but not to adverse pregnancy outcomes. Medscape Medical News source https://www.medscape.com/viewarticle/hydroxychloroquine-levels-tied-maternal-flares-sle-2024a1000bjp?src=rss

Researchers have found direct evidence that emotions are correlated with changes in gastric physiology. Medscape Medical News source https://www.medscape.com/viewarticle/biology-butterflies-stomach-2024a1000bjl?src=rss

Women with autoimmune liver diseases (AILD) may face increased risks for major adverse cardiovascular outcomes. MDedge News source https://www.medscape.com/s/viewarticle/women-autoimmune-liver-disease-face-higher-cvd-risks-2024a1000bj2?src=rss

Experts from throughout the region have provided guidelines for the monitoring system, although access to it remains challenging. Medscape Medical News source https://www.medscape.com/viewarticle/flash-glucose-monitoring-latin-american-recommendations-2024a1000bjk?src=rss

During his career, Bakris published more than 500 peer-reviewed manuscripts in the areas of hypertension, diabetic kidney disease and progression of nephropathy. Medscape Medical News source https://www.medscape.com/viewarticle/renowned-hypertension-expert-george-bakris-md-dies-2024a1000bg3?src=rss

The American Headache Society is backing CGRPs as first-line therapy for migraine prevention, but will the new guidance change clinical practice and, if so, how? Medscape Medical News source https://www.medscape.com/viewarticle/new-guidance-cgrps-first-line-migraine-prevention-how-will-2024a1000bg4?src=rss

About 28% of respondents reported itch improvement within 1 day of taking the drug. Medscape Medical News source https://www.medscape.com/viewarticle/survey-spotlights-real-world-experience-upadacitinib-atopic-2024a1000bfu?src=rss

Consumption of ultraprocessed food was associated with increased odds of constipation in a cross-sectional study of the US population. Medscape Medical News source https://www.medscape.com/viewarticle/ultraprocessed-food-linked-constipation-2024a1000bfv?src=rss

Clinicians should consider several factors when deciding whether to perform colonoscopy in elderly patients with dementia, including their pre-procedure clinical status. Medscape Medical News source https://www.medscape.com/viewarticle/balancing-risks-colonoscopy-elderly-patients-dementia-2024a1000bda?src=rss

Using combined genetic testing in early childhood may decrease the misdiagnosis rate for Global Development Delay (GDD). MDedge News source https://www.medscape.com/s/viewarticle/genetic-tests-may-help-identify-global-development-delay-2024a1000bd9?src=rss

Disparities in net worth by specialty, gender, and race persist, according to the 2024 Physician Wealth and Debt Report. Medscape Medical News source https://www.medscape.com/viewarticle/net-worth-rising-debt-falling-among-physicians-2024a1000bd6?src=rss

Dupilumab therapy was more effective than conventional treatments in reducing the risk of developing allergic rhinitis or asthma in children with atopic dermatitis. Medscape Medical News source https://www.medscape.com/viewarticle/does-dupilumab-affect-atopic-march-progression-children-2024a1000bd4?src=rss

Despite its accuracy, researchers warn that it may be too early to implement these recommendations in clinical practice. Medscape Medical News source https://www.medscape.com/viewarticle/chatgpt-accurately-defines-colonoscopy-screening-intervals-2024a1000b9u?src=rss

The agent is the first BiTE approved for consolidation regardless of MRD status. Medscape Medical News source https://www.medscape.com/viewarticle/blincyto-picks-new-bcp-all-indication-2024a1000b9t?src=rss

Two specialists debated the evidence on immunotherapy for cat allergy at a recent allergology conference. Medscape Medical News source https://www.medscape.com/viewarticle/immunotherapy-cat-allergy-effective-2024a1000b9r?src=rss

Patients with early-onset CRC did not have a greater risk for advanced polyps than their average-onset counterparts, calling into question their need for increased surveillance. Medscape Medical News source https://www.medscape.com/viewarticle/early-onset-crc-does-not-require-more-intense-surveillance-2024a1000b6v?src=rss

VTE risk increased in the month after bariatric surgery but was significantly lower than in nonsurgical control populations when follow-up was extended to a year and beyond. Medscape Medical News source https://www.medscape.com/viewarticle/bariatric-surgery-associated-vte-risk-decreases-long-term-2024a1000b6t?src=rss

Oral tranexamic acid added to triple combination cream therapy improves melasma outcomes. Medscape Medical News source https://www.medscape.com/viewarticle/oral-tranexamic-acid-boosts-melasma-outcomes-topical-2024a1000b6r?src=rss

Politics may override existing and emerging evidence that seems to support the benefits of safer supply programs. Medscape Medical News source https://www.medscape.com/viewarticle/are-canadas-safer-supply-programs-jeopardy-2024a1000b3x?src=rss

"Although skin involvement occurs in more than 80% of patients, it is pleomorphic and may resemble a variety of other conditions," Dr Edward W. Cowen said. Medscape Medical News source https://www.medscape.com/viewarticle/study-elucidates-skin-signs-vexas-syndrome-2024a1000b3w?src=rss

High-risk behaviours in young adults spell oral HPV. Medscape News UK source https://www.medscape.com/s/viewarticle/tale-two-tongues-oral-hpv-soars-young-adults-2024a1000ax7?src=rss

Rheumatoid arthritis disease activity influenced the severity of interstitial lung disease, an associated comorbidity, thereby affecting patients' prognosis, showed study. Medscape Medical News source https://www.medscape.com/viewarticle/rheumatoid-arthritis-disease-activity-impacts-severity-2024a1000b1j?src=rss

After decades of unwavering dedication, Michael Powe steps down from his role at the AAPA. He leaves behind a legacy of significant contributions to the physician assistant profession. Medscape Medical News source https://www.medscape.com/viewarticle/aapa-bids-adieu-michael-powe-tireless-pa-advocate-2024a1000b1g?src=rss

Medscape's 2024 Compensation Report shows an average jump of 6%. Medscape Medical News source https://www.medscape.com/viewarticle/physician-assistants-enjoying-modest-increase-compensation-2024a1000b1h?src=rss

Few studies have been conducted on the potential links between various irritants and food allergies. Medscape Medical News source https://www.medscape.com/viewarticle/can-chemical-agents-and-pollens-induce-food-allergies-2024a1000b1f?src=rss

Some pigments in permanent makeup products may cause allergic contact dermatitis, a study found. Medscape Medical News source https://www.medscape.com/viewarticle/permanent-makeup-pigments-linked-allergic-contact-dermatitis-2024a1000aym?src=rss

The novel method can predict dementia with greater than 80% accuracy and up to 9 years before a diagnosis using resting-state functional magnetic resonance imaging. Medscape Medical News source https://www.medscape.com/viewarticle/novel-method-able-predict-if-when-dementia-will-develop-2024a1000aw4?src=rss

Couples-based therapy called WePAP boosted treatment adherence for sleep apnea, leading to higher relationship satisfaction and lower levels of conflict, a study suggested. Medscape Medical News source https://www.medscape.com/viewarticle/couples-based-therapy-sleep-apnea-nurtures-happier-2024a1000aw1?src=rss

At a recent congress, experts discussed the points that need careful consideration when deciding whether to enroll a child with cancer in an end-of-life trial. Medscape Medical News source https://www.medscape.com/viewarticle/should-children-be-enrolled-end-life-clinical-studies-2024a1000avy?src=rss

When combined with clinical scores, a "game-changing" blood test can expedite the diagnosis and treatment of large vessel occlusion (LVO) stroke, new data suggested. Medscape Medical News source https://www.medscape.com/viewarticle/blood-test-game-changer-faster-diagnosis-treatment-lvo-2024a1000asr?src=rss

Researchers reported a case of pancreatitis in two patients taking tirzepatide. The risk for pancreatitis is expected to rise with increased prescriptions of these agents. Medscape Medical News source https://www.medscape.com/viewarticle/tirzepatide-woes-pancreatitis-strikes-raising-alarm-among-2024a1000asq?src=rss

Approximately one in eight older adults in the United States experiences traumatic brain injury, new data showed. Those with TBI are more likely to be wealthy, women, and White individuals. Medscape Medical News source https://www.medscape.com/viewarticle/shockingly-high-rate-tbi-older-adults-2024a1000asp?src=rss

The prevalence of posttraumatic stress disorder among college students doubled in a 5-year span from 3.4% to 7.5% in 2022, a new study showed. Medscape Medical News source https://www.medscape.com/viewarticle/ptsd-rates-soar-among-college-students-2024a1000asl?src=rss

Inebilizumab-cdon reduced the risk for flares by 87% in patients with IgG4-RD, the MITIGATE study showed. Medscape Medical News source https://www.medscape.com/viewarticle/inebilizumab-mitigates-flare-risk-igg4-related-disease-2024a1000apn?src=rss

Emerging evidence supports dietary modulation via the gut-liver axis in the management of patients with metabolic dysfunction-associated steatotic liver disease. MDedge News source https://www.medscape.com/s/viewarticle/microbiota-focused-dietary-therapy-could-improve-masld-2024a1000apj?src=rss

Hypogammaglobulinemia is a known risk linked to B-cell–depleting therapies, but a real-world study has specified the risk and risk factors in multiple sclerosis. Medscape Medical News source https://www.medscape.com/viewarticle/anti-cd20-hgg-linked-serious-infection-risk-ms-2024a1000api?src=rss

Many adults are complacent about vaccinations, believing that annual COVID and flu shots aside, they had all the immunizations they need as children and teens. MDedge News source https://www.medscape.com/s/viewarticle/five-vaccinations-adults-need-beyond-covid-and-flu-2024a1000am5?src=rss

Use of combined contraceptive vaginal rings was associated with an increased risk for several types of sexually transmitted infections (STIs). MDedge News source https://www.medscape.com/s/viewarticle/vaginal-ring-use-raises-risk-certain-stis-2024a1000am3?src=rss

Almost one third of physicians who endorsed drugs or devices on X don't disclose that they receive payments from the company, a new analysis found. Medscape Medical News source https://www.medscape.com/viewarticle/doctors-endorsing-products-x-may-not-disclose-company-ties-2024a1000am0?src=rss

Data from two phase 3 studies "support the use of bimekizumab as a promising new therapeutic option for patients with moderate to severe hidradenitis suppurativa," the authors concluded. Medscape Medical News source https://www.medscape.com/viewarticle/phase-3-trials-bimekizumab-effective-moderate-severe-2024a1000alz?src=rss

Although bothersome, gestational rhinitis can be managed through dietary, hygienic, and pharmacologic means. Medscape Medical News source https://www.medscape.com/viewarticle/gestational-rhinitis-how-can-we-manage-it-2024a1000aj0?src=rss

Behavioral strategies and pharmacologic treatments can prevent nausea and vomiting from spoiling vacation travel. Medscape Medical News source https://www.medscape.com/viewarticle/how-prevent-motion-sickness-land-sea-air-2024a1000aiw?src=rss

Semaglutide, found in Ozempic and Wegovy, reportedly improves sensitivity to taste, which helps change food preferences, leading to weight loss. WebMD Health News source https://www.medscape.com/s/viewarticle/ozempic-wegovy-improve-sense-taste-aiding-weight-loss-2024a1000ain?src=rss

Adults under 50 years who lived with obesity for a decade were up to 60% more likely to experience a cardiovascular event. Medscape Medical News source https://www.medscape.com/viewarticle/excess-weight-over-time-increases-risk-heart-attack-2024a1000afq?src=rss

Women who most closely followed the Mediterranean diet had a 20% lower risk for early death, according to a new study led by Harvard Medical School researchers. WebMD Health News source https://www.medscape.com/s/viewarticle/mediterranean-diet-linked-longer-life-among-women-2024a1000afo?src=rss

The most common presenting signs and symptoms of early-onset colorectal cancer include rectal bleeding, abdominal pain, and altered bowel habits, a new analysis found. Medscape Medical News source https://www.medscape.com/viewarticle/red-flags-early-onset-colorectal-cancer-identified-2024a1000afn?src=rss

Direct access colonoscopy was as effective as office-scheduled colonoscopy for completing screening or surveillance within 90 days of contacting the gastroenterology office. Medscape Medical News source https://www.medscape.com/viewarticle/direct-access-colonoscopy-saves-time-comparable-results-2024a1000abf?src=rss

A third dairy farm worker has been diagnosed with bird flu, the Michigan Department of Health & Human Services announced Thursday. WebMD Health News source https://www.medscape.com/s/viewarticle/bird-flu-affects-third-farm-worker-risk-public-still-low-2024a1000abe?src=rss

Half of adolescents who did fill prescriptions never reached their treatment dose, according to a single-center retrospective study. Medscape Medical News source https://www.medscape.com/viewarticle/glp-1-coverage-often-denied-teens-obesity-2024a1000ab6?src=rss

Oral corticotropin-releasing factor type 1 receptor antagonist enables glucocorticoid dosing at physiologic levels while maintaining androstenedione control. Medscape Medical News source https://www.medscape.com/viewarticle/crinecerfont-promising-congenital-adrenal-hyperplasia-2024a1000ab4?src=rss

Women taking the medication after 16 weeks better sensed lower concentrations of flavors and had notable changes in brain responses to sweet stimuli. Medscape Medical News source https://www.medscape.com/viewarticle/semaglutide-improves-taste-sensitivity-women-obesity-2024a1000ab3?src=rss

For patients with cancer, the increased financial burden of high-deductible health plans and delayed access to pain meds caused by prior authorization policies may harm patient well-being and survival. Medscape Medical News source https://www.medscape.com/viewarticle/high-deductible-health-plans-prior-authorization-can-harm-2024a1000aaz?src=rss

Five-year follow-up data from the landmark CROWN trial shows significant progression-free survival in ALK+ NCSLC, but some experts question the use of crizotinib as the comparator drug. Medscape Medical News source https://www.medscape.com/viewarticle/outstanding-5-year-progression-free-survival-lorlatinib-alk-2024a1000aas?src=rss

A virtual patient navigator improved colonoscopy uptake among a diverse and underserved population of English- and Spanish-speaking patients who had previously missed or avoided the procedure. Medscape Medical News source https://www.medscape.com/viewarticle/ai-patient-navigator-helps-re-engage-underserved-patients-2024a1000aao?src=rss