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Showing posts from February, 2024

Does an October Birthday Protect Kids From Flu?

New research showed that children born in October may have lower rates of influenza diagnosis. Medscape Medical News source https://www.medscape.com/viewarticle/does-october-birthday-protect-kids-flu-2024a100041q?src=rss

Mental Health Issues Tied to Worse Cancer Surgery Outcomes

Cancer patients with behavioral health disorders are less likely to have surgery and face worse outcomes when they do, according to a new study. MDedge News source https://www.medscape.com/s/viewarticle/mental-health-issues-tied-worse-cancer-surgery-outcomes-2024a100041o?src=rss

AHA Flags Barriers to Women in Interventional Specialties

Women remain underrepresented in interventional specialties, and reaching female medical students who might consider these specialties is one way to address the shortfall. Medscape Medical News source https://www.medscape.com/viewarticle/aha-flags-barriers-women-interventional-specialties-2024a10003ym?src=rss

What’s The Incidence Rate of a Second Primary Melanoma?

The findings may have potential implications for more personalized surveillance of patients with melanoma, the authors said. Medscape Medical News source https://www.medscape.com/viewarticle/older-age-confers-higher-risk-second-primary-melanoma-study-2024a10003yk?src=rss

Many Older Adults Don't Receive Palliative Care Before Death

A tool that estimates mortality risk could help clinicians determine which patients receiving home care are close to death and might benefit from palliative care. Medscape Medical News source https://www.medscape.com/viewarticle/many-older-adults-dont-receive-palliative-care-before-death-2024a10003vo?src=rss

Biological Sex Differences: Key to Understanding Long COVID?

New evidence continues to suggest a complicated link between sex hormone fluctuation and immune dysfunction in long COVID. Medscape Medical News source https://www.medscape.com/viewarticle/biological-sex-differences-key-understanding-long-covid-2024a10003vh?src=rss

Exercise for Depression as Effective as Meds, Psychotherapy

A new review shows exercise — especially intense yoga, walking, jogging, and strength training — is an effective treatment for depression. Medscape Medical News source https://www.medscape.com/viewarticle/exercise-depression-effective-meds-psychotherapy-2024a10003s0?src=rss

National Rapid Genome Testing Program Benefits NICU Care

An Israeli study showed the feasibility and diagnostic benefits of rapid trio genome sequencing in critically ill neonates. Medscape Medical News source https://www.medscape.com/viewarticle/national-rapid-genome-testing-program-benefits-nicu-care-2024a10003rz?src=rss

Scents May Improve Memory in Major Depression

Scents were more effective than word cues at triggering specific, vivid autobiographical memories in people with depression, which could reduce deficits in memory recall. Medscape Medical News source https://www.medscape.com/viewarticle/scents-may-improve-memory-major-depression-2024a10003rx?src=rss

Managing Asparaginase Toxicity in ALL

Asparaginase remains a mainstay of ALL treatment despite challenging side effects, with clinicians continuously adjusting therapy and developing new strategies to mitigate toxicity. MDedge News source https://www.medscape.com/s/viewarticle/managing-asparaginase-toxicity-all-2024a10003pn?src=rss

Biologic Treatment for Psoriasis Linked to Lower Mortality

Evidence to support the hypothesis that the use of systemic immunomodulatory agents for psoriasis "quenches systemic inflammation and potentially improves" survival is limited, investigators said. MDedge News source https://www.medscape.com/s/viewarticle/biologic-treatment-psoriasis-linked-lower-mortality-2024a10003pl?src=rss

Long-Term Ixekizumab Use Shows Solid Safety Data

Final safety results from 25 randomized clinical trials were consistent with previous reports at up to 6 years' follow-up. Medscape Medical News source https://www.medscape.com/viewarticle/long-term-ixekizumab-use-shows-solid-safety-data-across-25-2024a10003pj?src=rss

'Eating As Treatment' Linked to Improved Survival in HNC

An oncology dietician-led intervention improved nutritional status and significantly reduced 5-year mortality in patients with head and neck cancer undergoing radiotherapy. Medscape Medical News source https://www.medscape.com/viewarticle/eating-treatment-linked-improved-survival-hnc-2024a10003pi?src=rss

Are AI Tools the Future of Mammography Screening?

Early signs show AI in breast cancer screenings may enhance diagnosis, but questions persist on optimal integration and timely deployment. MDedge News source https://www.medscape.com/s/viewarticle/are-ai-tools-future-mammography-screening-2024a10003lg?src=rss

Longer IV Ertapenem Course Beneficial for Recalcitrant HS

2019 treatment guidelines published recommended ertapenem as a highly effective third-line therapy limited to a shorter course, as rescue therapy or during surgical planning. MDedge News source https://www.medscape.com/s/viewarticle/longer-iv-ertapenem-course-beneficial-recalcitrant-2024a10003lc?src=rss

Curbing Antibiotic Use Works

European agencies published evidence that reducing antibiotic use in humans and food-producing animals leads to a decline in antimicrobial resistance. Medscape Medical News source https://www.medscape.com/viewarticle/curbing-antibiotic-use-works-2024a10003lf?src=rss

Forget the Shots: Focusing on Gut Health Can Aid Weight Loss

Because the lower part of the gut makes hormones, among them GLP-1, that help orchestrate metabolism and appetite, giving microbes the right fuel through food can stimulate the gut to make them. WebMD Health News source https://www.medscape.com/s/viewarticle/forget-shots-focusing-gut-health-can-aid-weight-loss-2024a10003ld?src=rss

'Deep Phenotyping' Identifies Abnormalities in ME/CFS

New research from the National Institutes of Health identified "clear objective changes" in people with postinfectious myalgic encephalomyelitis/chronic fatigue syndrome. Medscape Medical News source https://www.medscape.com/viewarticle/deep-phenotyping-identifies-abnormalities-me-cfs-2024a10003ic?src=rss

Empagliflozin Sheds Liver Fat in People With and Without T2D

Empagliflozin reduced liver fat content in patients with obesity and patients with type 2 diabetes. Medscape Medical News source https://www.medscape.com/viewarticle/empagliflozin-sheds-liver-fat-people-and-without-t2d-2024a10003ie?src=rss

Does the Internet Protect the Elderly From Cognitive Decline?

A large longitudinal study suggests that older adults who regularly use the Internet for less than 2 hours per day have a decreased risk for dementia. Medscape Medical News source https://www.medscape.com/viewarticle/does-internet-protect-elderly-cognitive-decline-2024a10003if?src=rss

Perceived vs Actual Cognitive Impairment in Prostate Cancer

Following hormone therapy, patients with prostate cancer may perceive an increase in cognitive issues, despite tests showing no objective decline, a recent meta-analysis found. Medscape Medical News source https://www.medscape.com/viewarticle/perceived-vs-actual-cognitive-impairment-prostate-cancer-2024a10003id?src=rss

Cushing Remission After Surgery May Raise Autoimmune Risk

The findings suggested the need for closer postsurgical monitoring of patients with a family history of autoimmune disease. Medscape Medical News source https://www.medscape.com/viewarticle/cushing-disease-remission-after-surgery-linked-increased-2024a10003g8?src=rss

FDA Authorizes Sleep Apnea App

New feature was designed to detect early signs of sleep apnea via watch or phone. Medscape Medical News source https://www.medscape.com/viewarticle/fda-authorizes-sleep-apnea-app-2024a10003g3?src=rss

AHA: Urgent Need to Reduce Maternal Postpartum CVD Risk

Society panel hopes identifying at-risk women at younger ages will enable prevention through lifestyle changes and timely treatment. MDedge News source https://www.medscape.com/s/viewarticle/aha-urgent-need-reduce-maternal-postpartum-cvd-risk-2024a10003g4?src=rss

FDA Approves Iloprost for Severe Frostbite

Iloprost significantly reduced the risk for amputation resulting from severe frostbite. Medscape Medical News source https://www.medscape.com/viewarticle/fda-approves-iloprost-severe-frostbite-2024a10003cn?src=rss

Bariatric Surgery Yields Significant Cognitive Benefits

Bariatric surgery has long-term health benefits that go beyond weight loss, including improved cognition and brain structure and function, new research indicated. Medscape Medical News source https://www.medscape.com/viewarticle/bariatric-surgery-yields-significant-cognitive-benefits-2024a10003dq?src=rss

Focal Therapy for Prostate Cancer: Is It Being Oversold?

Despite growing enthusiasm for this minimally invasive option for some men with prostate cancer, focal therapy is still not FDA-approved for prostate cancer and comes with high out-of-pocket costs. Medscape Medical News source https://www.medscape.com/viewarticle/focal-therapy-prostate-cancer-evidence-based-or-oversold-2024a10003do?src=rss

Examining the Global Decline in Fertility

Researchers describe regional differences in the decline in fertility, which has been significant for about 20 years. Medscape Medical News source https://www.medscape.com/viewarticle/examining-global-decline-fertility-2024a10003dn?src=rss

Overdose-Attributed Cardiac Arrests Show Better Survival

Cardiac arrests due to drug overdose showed higher survival with better neurologic outcomes when the first monitored rhythm was nonshockable. Medscape Medical News source https://www.medscape.com/viewarticle/overdose-attributed-cardiac-arrests-show-better-survival-2024a10003bo?src=rss

Who Benefits From Beta Blocker Withdrawal in HFpEF?

A new study suggested indexed left ventricular systolic volume may predict benefit of beta blocker withdrawal in patients with heart failure with preserved ejection fraction. Medscape Medical News source https://www.medscape.com/viewarticle/who-benefits-beta-blocker-withdrawal-hfpef-2024a10003bm?src=rss

Benefit of Late Thrombolysis in Large Vessel Strokes?

Some patients with large vessel occlusion strokes may still benefit from thrombolysis even after the traditional 4.5-hour window, new analysis of the TIMELESS trial suggested. Medscape Medical News source https://www.medscape.com/viewarticle/benefit-late-thrombolysis-large-vessel-strokes-2024a10003bl?src=rss

Does Canadian Pediatric Hypertension Care Follow Guidelines?

More than 6 years after new guidelines were introduced, care remains suboptimal, data suggested. Medscape Medical News source https://www.medscape.com/viewarticle/does-canadian-pediatric-hypertension-care-follow-guidelines-2024a10003bi?src=rss

Playing Music Tied to Better Cognition in Later Life

Playing a musical instrument or singing in a musical group was associated with better working memory and executive function, new study results showed. Medscape Medical News source https://www.medscape.com/viewarticle/playing-music-tied-better-cognition-later-life-2024a100039m?src=rss

Cellulite: Outcomes 1 Year After Noninvasive Treatment

The findings build on results from a 12-week study of the device, which the investigators said "induces physical shearing of fibrous septa through rapid acoustic pulses." MDedge News source https://www.medscape.com/s/viewarticle/acoustic-subcision-cellulite-results-1-year-after-treatment-2024a100039k?src=rss

Tapinarof Under FDA Review for Treating Atopic Dermatitis

Approved in 2022 for psoriasis, the manufacturer has submitted an application for approval of tapinarof cream for treating atopic dermatitis in adults and children 2 years of age and older. MDedge News source https://www.medscape.com/s/viewarticle/topical-tapinarof-under-fda-review-new-indication-atopic-2024a100039i?src=rss

Parent-Led Digital CBT Effective for Childhood Anxiety

Parent-led digital cognitive behavioral therapy, with remote therapist support, worked as well as traditional CBT while saving therapist time and money, in a controlled trial. Medscape Medical News source https://www.medscape.com/viewarticle/parent-led-digital-cbt-effective-childhood-anxiety-2024a100036x?src=rss

Adverse Pregnancy Outcomes Often Strike Twice

Problems that surface during a first pregnancy are more likely to occur during a second, a new study found. MDedge News source https://www.medscape.com/s/viewarticle/adverse-pregnancy-outcomes-often-strike-twice-2024a100036v?src=rss

Canadian Medical Groups Unite to Demand Government Action

Ontario's $3 billion pact with the federal government is a significant step, but further reforms are needed nationwide, doctors said. Medscape Medical News source https://www.medscape.com/viewarticle/canadian-medical-groups-demand-government-act-fix-systems-2024a100036m?src=rss

CAR T Cell: Do Benefits Still Outweigh Risks?

Despite concerns about the development of secondary T-cell malignancies due to CAR T-cell immunotherapy, experts still believed that the benefits outweigh the risks. MDedge News source https://www.medscape.com/s/viewarticle/car-t-cell-do-benefits-still-outweigh-risks-2024a100036l?src=rss

Immune Response May Cause Virus-Induced Neurologic Damage

Results from a mouse model could lead to the development of therapies to prevent neurologic damage caused by viruses such as Zika. Medscape Medical News source https://www.medscape.com/viewarticle/immune-response-may-cause-virus-induced-neurologic-damage-2024a1000340?src=rss

Tinea Capitis Management in Kids Varies, Survey Finds

Respondents included 56 members of the Pediatric Dermatology Research Alliance. Medscape Medical News source https://www.medscape.com/viewarticle/management-tinea-capitis-varies-among-pediatric-2024a100033w?src=rss

Surgery Shows Longer-Term Benefits for Dupuytren Contracture

At 2 years out, surgery was more successful than other treatments, a randomized controlled trial found. MDedge News source https://www.medscape.com/s/viewarticle/surgery-shows-longer-term-benefits-dupuytren-contracture-2024a100031x?src=rss

Subdural Hematoma Embolization Success Cuts Surgery Need

Three new randomized trials, EMBOLISE, MAGIC-MT, and STEM, showed convincing benefits for use of an endovascular embolization procedure in patients with a subdural hematoma. Medscape Medical News source https://www.medscape.com/viewarticle/subdural-hematoma-embolization-success-cuts-surgery-need-2024a100031u?src=rss

Higher Risk for Death After Benzodiazepine Discontinuation

These medications must be tapered slowly to avoid causing severe withdrawal symptoms, said an addiction medicine specialist. Medscape Medical News source https://www.medscape.com/viewarticle/higher-risk-death-after-benzodiazepine-discontinuation-2024a100031r?src=rss

Tirofiban Reduces Early Deterioration After Stroke

Intravenous tirofiban over 72 hours reduced early neurologic deterioration compared with oral aspirin in patients with acute ischemic stroke, in the randomized TREND trial. Medscape Medical News source https://www.medscape.com/viewarticle/tirofiban-reduces-early-neurologic-deterioration-after-2024a10002yk?src=rss

Which Patients Benefit From Endocrine Therapy Past 5 Years?

Japanese investigators identified a group of patients with breast cancer who demonstrated improved long-term outcomes on endocrine therapy beyond the usual 5 years. Medscape Medical News source https://www.medscape.com/viewarticle/which-patients-breast-cancer-can-benefit-endocrine-therapy-2024a10002yl?src=rss

Higher Doses of Opioid Reversal Agent Offer No Clear Benefit

Researchers sought to find out if administering 8 mg rather than 4 mg of naloxone increased the odds of survival after an overdose. Medscape Medical News source https://www.medscape.com/viewarticle/higher-dose-naloxone-has-no-impact-overdose-survival-2024a10002yj?src=rss

Assessing the Case for AI Regulations in Healthcare

Explore the delicate balance between innovation and patient safety as policymakers navigate the ever-evolving landscape of artificial intelligence in medicine. Medscape Medical News source https://www.medscape.com/viewarticle/minding-machine-assessing-case-ai-regulations-healthcare-2024a10002yi?src=rss

Some Alcohol-Related Hospitalizations Tied to Poor Outcomes

Patients hospitalized for alcohol-related harms are a diverse population, and those with liver disease face the highest risks for in-hospital and post-discharge mortality. Medscape Medical News source https://www.medscape.com/viewarticle/some-alcohol-related-hospitalizations-tied-poor-outcomes-2024a10002yg?src=rss

Prenatal and congenital syphilis cases continue sharp rise in the U.S.

Last November, the Centers for Disease Control and Prevention (CDC) reported that cases of congenital syphilis in the U.S. had soared 755% over the past decade, peaking at more than 3,700 in 2022 . The CDC’s review of that year’s cases revealed that nearly 90% were potentially preventable, resulting from a lack of timely testing and adequate treatment. An analysis of 2017-2019 Medicaid claims in 6 Southern states (Georgia, Kentucky, Louisiana, North Carolina, South Carolina, and Tennessee) found that despite state laws mandating prenatal syphilis screening, actual screening rates ranged from 56% to 91%. In a  previous blog post , I discussed how the diversion of public health personnel and resources during the COVID-19 pandemic had hampered contact tracing efforts to prevent the spread of syphilis and other sexually transmitted infections (STIs). Since June 2023, syphilis treatment has been affected by a global shortage of injectable benzathine penicillin , leading the CDC to advise

Xylazine Increasingly Found in Canada's Illegal Drug Supply

The drug, a tranquilizer for animals including horses and cattle, is hard for clinicians to identify, and users may not even know they have taken it. Medscape Medical News source https://www.medscape.com/viewarticle/animal-tranquilizer-xylazine-increasingly-found-canadas-2024a10002vp?src=rss

How to Prescribe Physical Activity in Patients With Obesity

Current recommendations may not be aligned with the needs of patients with obesity, according to one expert. Medscape Medical News source https://www.medscape.com/viewarticle/how-prescribe-physical-activity-patients-obesity-2024a10002vo?src=rss

Study Shows Disparities in Diagnosing Across Skin Tones

Across all images, diseases in darker skin types were diagnosed less accurately than diseases in lighter skin types, including when decision support from a deep learning system was introduced. MDedge News source https://www.medscape.com/s/viewarticle/despite-ai-assist-study-shows-disparities-diagnosing-across-2024a10002vm?src=rss

Belantamab Mafodotin Tops Daratumumab in Multiple Myeloma

The phase 3 study findings supported belantamab mafodotin as a potential new standard of care in the second line or later among patients with released/refractory multiple myeloma. Medscape Medical News source https://www.medscape.com/viewarticle/belantamab-mafodotin-tops-daratumumab-multiple-myeloma-2024a10002vl?src=rss

Immune-Related AEs Predict Outcomes in Advanced GU Cancers

Patients with advanced GU cancers who had immune-related AEs from immunotherapy had better overall survival — a phenomenon also reported for other cancer types. Medscape Medical News source https://www.medscape.com/viewarticle/immune-related-adverse-events-predict-outcomes-advanced-2024a10002qk?src=rss

Tirzepatide Reduces BP but Most Likely Due to Weight Loss

Now-published substudy of the SURMOUNT-1 trial shows a "bonus effect" of the medication, study author said. Medscape Medical News source https://www.medscape.com/viewarticle/tirzepatide-reduces-bp-most-likely-due-weight-loss-2024a10002qi?src=rss

Long-Acting Injectables Curb Schizophrenia Readmission

Patients with schizophrenia discharged on an LAI antipsychotic had significantly lower 30-day psychiatric readmission rates than those sent home with an oral antipsychotic. Medscape Medical News source https://www.medscape.com/viewarticle/long-acting-injectable-antipsychotics-reduce-schizophrenia-2024a10002nf?src=rss

Preventing Autoimmune Diseases: New Vit. D, Omega-3 Findings

Omega-3 fatty acid supplements prevented autoimmune diseases for 2 years after cessation, but vitamin D's effects tapered off, suggesting that continuous dosing is warranted. Medscape Medical News source https://www.medscape.com/viewarticle/preventing-autoimmune-diseases-new-findings-vitamin-d-omega-2024a10002nc?src=rss

Physician Fined $25K Over Supervision of DNP Who Called Herself 'Doctor'

An ob/gyn must pay a $25,000 fine for failing to adhere to the collaborative agreement she entered with a California nurse practitioner who called herself "Dr Sarah." Medscape Medical News source https://www.medscape.com/viewarticle/physician-fined-25k-over-supervision-dnp-who-called-herself-2024a10002ky?src=rss

Harvard Docs Train Ukrainian Counterparts 2 Years Into War

Boston program aimed to mentor specialists whose medical education was forged in the remnants of the old Soviet system. Medscape Medical News source https://www.medscape.com/viewarticle/harvard-docs-train-ukrainian-counterparts-2-years-war-2024a10002kv?src=rss

Disparities Seen in Weight Loss Drug Prescriptions, Fills

Biological sex, ethnicity, socioeconomic status, and insurance type all play a role in prescribing weight loss medications. Medscape Medical News source https://www.medscape.com/viewarticle/disparities-seen-weight-loss-drug-prescriptions-fills-2024a10002ku?src=rss

Dupilumab Improves AD Affecting the Hands, Feet

Dupilumab monotherapy was an effective and safe systemic treatment for patients with moderate to severe hand and foot atopic dermatitis. Medscape Medical News source https://www.medscape.com/viewarticle/dupilumab-improves-ad-affecting-hands-feet-2024a10002ks?src=rss

EDs Need Better Strategies to Minimize Nonurgent Visits

A study revealed significant discrepancies between presenting reasons for ED visits and discharge diagnoses, necessitating alternative methods to identify nonurgent conditions. Medscape source https://www.medscape.com/viewarticle/eds-need-better-strategies-minimize-nonurgent-visits-2024a10002gf?src=rss

Canada Delays Medically Assisted Death for Mental Illness

Canada has postponed a legal change needed to permit medical assistance in dying in cases of mental illnesses. Medscape Medical News source https://www.medscape.com/viewarticle/canada-delays-medically-assisted-death-mental-illness-2024a10002gs?src=rss

Night Bracing: A Good Alternative for Adolescent Scoliosis

Bracing alone is not enough to achieve success; hours worn and exercise are also key, a new study found. MDedge News source https://www.medscape.com/s/viewarticle/night-bracing-good-alternative-adolescent-scoliosis-2024a10002fu?src=rss

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Triglyceride Glucose Index May Predict Cardio Risks

In patients with well-controlled cholesterol after a percutaneous coronary intervention, a higher triglyceride glucose index was tied to higher incidence of adverse clinical outcomes. Medscape Medical News source https://www.medscape.com/viewarticle/triglyceride-glucose-index-may-predict-cardio-risks-2024a10002bc?src=rss

Cardiorespiratory Fitness May Cut Prostate Cancer Risk

A new study adds to evidence that exercise reduces all-cause mortality risk across many cancer types, including prostate. MDedge News source https://www.medscape.com/s/viewarticle/cardiorespiratory-fitness-may-cut-prostate-cancer-risk-2024a10002b8?src=rss

Team IDs Key Factors for Synthetic Control Arm in Mets CRC

Researchers identified a handful of prognostic factors to create a synthetic control arm, which can ultimately replace placebo control arms in future trials of salvage-line metastatic CRC. Medscape Medical News source https://www.medscape.com/viewarticle/team-identifies-key-factors-synthetic-control-arm-metastatic-2024a10002ay?src=rss