Sharon Smith

Adverse childhood experiences, including physical abuse and neglect, were found to be important risk factors for adult primary headache disorders. Medscape Medical News source https://www.medscape.com/viewarticle/997903?src=rss

Belgium’s drug regulator said it had seized counterfeit versions of semaglutide, the active ingredient in Novo Nordisk's popular obesity drug Wegovy, in which the injector pens contained insulin. Reuters Health Information source https://www.medscape.com/s/viewarticle/997879?src=rss

Older patients with higher triglyceride levels, mostly within the normal to high range, had lower risk of dementia and slower cognitive decline over time than those with lower triglyceride levels. Medscape Medical News source https://www.medscape.com/viewarticle/997898?src=rss

If left untreated, hyperthyroidism can lead to cardia arrhythmias and osteoporosis. A new review summarizes recent evidence regarding the treatment of hyperthyroidism. Medscape Medical News source https://www.medscape.com/viewarticle/997861?src=rss

When Novo Nordisk publishes third-quarter results next week investors and analysts are hoping the company will clarify when limits on the supply of starter doses of its weight-loss drug Wegovy in the United States will cease. Reuters Health Information source https://www.medscape.com/s/viewarticle/997802?src=rss

Healthcare companies who profit from treating obese and overweight patients are trying to convince investors that powerful new weight-loss drugs won't shrink their businesses. Reuters Health Information source https://www.medscape.com/s/viewarticle/997800?src=rss

Researchers identified a higher risk for inflammatory bowel disease among adults who consumed a diet rich in ultraprocessed foods. MDedge News source https://www.medscape.com/s/viewarticle/997855?src=rss

Laboratory Corporation of America topped Wall Street expectations for quarterly adjusted profit on Thursday, as strength in its routine diagnostics business more than offset weak COVID test sales. Reuters Health Information source https://www.medscape.com/s/viewarticle/997758?src=rss

Merck on Thursday reported higher-than-expected third-quarter results on surprisingly strong demand for its COVID-19 treatment, primarily in Japan, and raised its sales forecast for the drug. Reuters Health Information source https://www.medscape.com/s/viewarticle/997750?src=rss

Researchers report endoscopic features and propose diagnostic criteria for post–COVID-19 cholangiopathy — one of the most serious long-term gastrointestinal consequences of COVID-19. Medscape Medical News source https://www.medscape.com/viewarticle/997809?src=rss

Bavarian Nordic said on Wednesday a CDC panel has voted in favor of recommending the routine use of Jynneos vaccine for adults at risk of mpox. Reuters Health Information source https://www.medscape.com/s/viewarticle/997726?src=rss

MDedge News source https://www.medscape.com/s/viewarticle/997749?src=rss

Serum vitamin D levels were lower and the prevalence of vitamin D deficiency was higher in patients with ulcerative colitis compared with controls. Medscape Medical News source https://www.medscape.com/viewarticle/997746?src=rss

Can testosterone replacement therapy help postmenopausal patients restore libido and improve overall health and vitality? Medscape Medical News source https://www.medscape.com/viewarticle/997703?src=rss

Medscape looked at some of the important metrics that oncology practices track to ensure that their revenue, clinical processes, and patient care procedures shape their success. Medscape Medical News source https://www.medscape.com/viewarticle/997711?src=rss

The FDA approval was based on a small study, in which 38.9% of patients with relapsed or refractory disease went into complete remission. Medscape Medical News source https://www.medscape.com/viewarticle/997704?src=rss

The study findings underscore the importance of enhancing clinician-patient communication, the authors say. Medscape Medical News source https://www.medscape.com/viewarticle/997699?src=rss

Oleogel-S10 reduced the need for daily dressing changes compared with a control gel in patients with epidermolysis bullosa, according to a further analysis of data from the phase 3 EASE study. Medscape Medical News source https://www.medscape.com/viewarticle/997669?src=rss

Treatment with 5-MeO-DMT and ibogaine was associated with reduced PTSD, depression, anxiety, and even postconcussive symptom scores for up to 6 months in veterans. Medscape Medical News source https://www.medscape.com/viewarticle/997652?src=rss

An ESMO session highlights the well-known links between alcohol consumption and cancer and calls on healthcare professionals to do more to raise awareness among patients. Medscape Medical News source https://www.medscape.com/viewarticle/997665?src=rss

The US health regulator has approved the expanded use of BioMarin Pharmaceutical's once-daily injection to treat children under the age of 5 with the most common form of short-limbed dwarfism. Reuters Health Information source https://www.medscape.com/s/viewarticle/997595?src=rss

Three listed Chinese drugmakers used parts of endangered animals as ingredients in their products, an environmental group said in a report published Monday. Reuters Health Information source https://www.medscape.com/s/viewarticle/997610?src=rss

The senator has called on the chief executive of 23andMe to provide the panel with details after data from the family genetics website was advertised for sale on the dark web. Reuters Health Information source https://www.medscape.com/s/viewarticle/997584?src=rss

Researchers point to missed opportunities for improving preterm birth data. Medscape Medical News source https://www.medscape.com/viewarticle/997620?src=rss

Two noninvasive tests in development, one measuring RNA and the other DNA, show high sensitivity for detection of colorectal cancer. Medscape Medical News source https://www.medscape.com/viewarticle/997609?src=rss

Pembrolizumab improved progression-free survival when added to standard chemoradiotherapy in newly diagnosed, locally advanced cervical cancer, new data show. MDedge News source https://www.medscape.com/s/viewarticle/997608?src=rss

The fast pace of progress in endometrial cancer has taken a step forward with two trials underlining the benefit of immunotherapy plus chemo, while suggesting adding a PARP inhibitor could further boost outcomes. Medscape Medical News source https://www.medscape.com/viewarticle/997607?src=rss

Interim findings from the ALINA trial show improved DFS with alectinib in the adjuvant setting vs chemotherapy in resected stage IB-IIIA NSCLC. But will early DFS results extend to overall survival? Medscape Medical News source https://www.medscape.com/viewarticle/997606?src=rss

Interim findings from CheckMate 77T show an overall improvement in event-free survival with perioperative nivolumab vs neoadjuvant nivolumab plus chemotherapy only. Medscape Medical News source https://www.medscape.com/viewarticle/997604?src=rss

Real-world data show endoscopic sleeve gastroplasty is safe and leads to significant and sustained weight loss, even in patients with class III obesity. Medscape Medical News source https://www.medscape.com/viewarticle/997603?src=rss

Building on prior studies, a new trial shows that digital symptom monitoring during cancer treatment detects symptoms early, improves quality of life, and reduces hospital visits. Medscape Medical News source https://www.medscape.com/viewarticle/997601?src=rss

Adding the CDK4/6 inhibitor to endocrine therapy among women with high-risk early breast cancer continues to show modest but clinically significant benefits 5 years in, compared with endocrine therapy alone. MDedge News source https://www.medscape.com/s/viewarticle/997600?src=rss

Playing chess or other board games slows cognitive decline and improves quality of life in older patients, results of a new systematic review suggest. Medscape Medical News source https://www.medscape.com/viewarticle/997571?src=rss

How prevalent are clinically important traumatic injuries among children presenting with a drowning encounter? Should radiographic studies be the general norm for assessing trauma in these children? Medscape Medical News source https://www.medscape.com/viewarticle/997565?src=rss

Successful first-attempt peripheral intravenous cannulation in patients with difficult venous access can avoid delays in administering medications in the emergency department. Is bi-plane imaging the long-sought answer? Medscape Medical News source https://www.medscape.com/viewarticle/997562?src=rss

Extension trial gives insight into treatment order for a little-studied population of premenopausal women. Medscape Medical News source https://www.medscape.com/viewarticle/997529?src=rss

Dapagliflozin became the first SGLT2 inhibitor approved for CKD alone just over 2 years ago, but uptake has lagged. Could a similar label gain for empagliflozin, plus a new recommendation, spark change? Medscape Medical News source https://www.medscape.com/viewarticle/997528?src=rss

Clinicians 'should be reassured' that patients with obesity and on antidepressants who don't have major depressive disorder or suicidality in the past 2 years can receive semaglutide, says a researcher. Medscape Medical News source https://www.medscape.com/viewarticle/997492?src=rss

Maybe one of your patients can join a new clinical trial in colorectal cancer. Medscape Medical News source https://www.medscape.com/viewarticle/997525?src=rss

The continuing shortage of antiobesity medications sends many patients to compounding pharmacies, but at what risk? Medscape Medical News source https://www.medscape.com/viewarticle/997481?src=rss

Participants taking estetrol experienced beneficial changes across a variety of metabolic measures, according to a new study presented at the Menopause Society. MDedge News source https://www.medscape.com/s/viewarticle/997443?src=rss

Although the findings are suggestive, they don’t definitively pin blame on tricyclic antidepressants alone in directly leading to fractures. Medscape Medical News source https://www.medscape.com/viewarticle/997440?src=rss

Coexisting pulmonary hypertension may be a marker for disease severity among patients with acute respiratory distress syndrome. Medscape Medical News source https://www.medscape.com/viewarticle/997434?src=rss

Preliminary real-world audit data show reduced A1c among men who received testosterone replacement therapy over a 2-year period. Medscape Medical News source https://www.medscape.com/viewarticle/997431?src=rss

Roughly one in eight peri- and postmenopausal women say they use cannabis for medical reasons, according to a new study presented at the 2023 annual meeting of The Menopause Society. MDedge News source https://www.medscape.com/s/viewarticle/997393?src=rss

People are accessing antibiotics unsafely to self-medicate symptoms, report researchers, who say that patients need easier access to care and education about how antibiotics actually work. Medscape Medical News source https://www.medscape.com/viewarticle/997383?src=rss

Phase 3b results show risankizumab is superior for endoscopic remission and clinical remission at week 48 compared with ustekinumab, a "once in a career" result, study authors say. Medscape Medical News source https://www.medscape.com/viewarticle/997377?src=rss

Final data from SURMOUNT-3 (tirzepatide), real-world experience with the latest antiobesity drugs, a standards-of-care document in the works, and more will be featured at Obesity Week 2023 in Dallas. Medscape Medical News source https://www.medscape.com/viewarticle/997344?src=rss

The use of doublet therapy has increased survival by 6 months, on average, in men with de novo metastatic castration-sensitive prostate cancer, according to Swedish registry data. Medscape Medical News source https://www.medscape.com/viewarticle/997343?src=rss

Walgreens Boots Alliance has said it expected to cut at least $1 billion in costs in 2024 as part of its ongoing efforts, which include shutting unprofitable stores. Reuters Health Information source https://www.medscape.com/s/viewarticle/997291?src=rss

Hematologists are heralding a new era in multiple myeloma. Experts discuss how times have changed. MDedge News source https://www.medscape.com/s/viewarticle/997299?src=rss

It may be possible to predict progression of type 2 diabetes in kids with prediabetes through a few important screening tests — notably A1c plus nonfasting glucose — and possibly stop it in its tracks. Medscape Medical News source https://www.medscape.com/viewarticle/997296?src=rss

Wastewater monitoring is an established tool for tracking COVID, and now new evidence shows it can be used alongside clinical testing to assess the burden of influenza and RSV in communities. Medscape Medical News source https://www.medscape.com/viewarticle/997294?src=rss

Overall, cancer clinicians, patient advocates, researchers, and others rated patient-centered factors, especially quality of life, as top priorities in delivering value-based cancer care, a new survey shows. Medscape Medical News source https://www.medscape.com/viewarticle/997292?src=rss

The recently approved 8-mg dose of aflibercept has shown sustained improvement in vision and anatomical markers out to 96 weeks, according to updated clinical trial results. Medscape Medical News source https://www.medscape.com/viewarticle/997288?src=rss

A novel investigational antiseizure medication reduces seizure frequency by more than 50% in some patients with treatment-resistant focal epilepsy. Medscape Medical News source https://www.medscape.com/viewarticle/997258?src=rss

The march of immunotherapy into a wider range of malignancies, as well as the smarter use of chemotherapy and novel targeted drugs, will be among the key highlights at the ESMO Congress 2023. Medscape Medical News source https://www.medscape.com/viewarticle/997257?src=rss

Walmart said on Tuesday it will expand online primary care benefits as part of its employee health insurance plan to its workers in 28 US states. Reuters Health Information source https://www.medscape.com/s/viewarticle/997213?src=rss

As many as 2 out of 3 people with long COVID also have mental health challenges, including high rates of depression and anxiety, new research shows. Medscape Medical News source https://www.medscape.com/viewarticle/997209?src=rss

The prevalence of attention-deficit/hyperactivity disorder (ADHD) among US children and adolescents remained stable at around 10% from 2017 through 2022, new data show. Medscape Medical News source https://www.medscape.com/viewarticle/997211?src=rss

The terminology that clinicians use to talk about treatments for obesity may contribute to stigma and poor adherence. Medscape Medical News source https://www.medscape.com/viewarticle/997207?src=rss

A federal judge in Oklahoma has allowed a state law banning gender-affirming care for transgender minors to take effect, adding to a growing split among courts on whether such laws can be enforced. Reuters Health Information source https://www.medscape.com/s/viewarticle/997169?src=rss

Pharmacy employees at some U.S. Walgreens stores, including pharmacists, technicians and support staff, plan a walkout between Monday and Wednesday, CNN reported, citing an organizer. Reuters Health Information source https://www.medscape.com/s/viewarticle/997173?src=rss

Soon-to-be-published consensus report will remove glucose from the definition of diabetic ketoacidosis in people with diabetes, among many other changes since the last statement in 2009. Medscape Medical News source https://www.medscape.com/viewarticle/997186?src=rss

Compared with men, women receive a diagnosis of rheumatic disease much later and are treated more poorly, research suggests. Medscape Medical News source https://www.medscape.com/viewarticle/997183?src=rss

Lead is significantly more harmful to the health of children and adults across the world than previously thought, according to a modeling study. Medscape Medical News source https://www.medscape.com/viewarticle/997182?src=rss

Metabolic dysfunction–associated steatotic liver disease (MASLD) was associated with increased risks for hepatic and extrahepatic complications in a large meta-analysis. Medscape Medical News source https://www.medscape.com/viewarticle/997178?src=rss

Patients with limited-stage small cell lung cancer demonstrated better overall and progression-free survival on higher-dose thoracic radiotherapy vs standard treatment, new data show. MDedge News source https://www.medscape.com/s/viewarticle/997157?src=rss

Those who discontinued the "twincretin" drug after 36 weeks regained weight but still maintained some weight loss at 1 year. Medscape Medical News source https://www.medscape.com/viewarticle/997152?src=rss

In a meta-analysis, researchers concluded that surgery does not improve survival and "should not be routinely offered to patients with metastatic disease." Medscape Medical News source https://www.medscape.com/viewarticle/997155?src=rss

Adults transitioning from male to female showed significant changes in forehead measures after surgery. Medscape Medical News source https://www.medscape.com/viewarticle/997154?src=rss

Patients receiving prophylactic colchicine or NSAIDs with initiation of allopurinol for gout have more adverse events than those who receive no prophylaxis, but these events are rare overall. Medscape Medical News source https://www.medscape.com/viewarticle/997150?src=rss

Patients with more severe COVID-19 that required hospitalization in the ICU were more likely to develop vasculitis, alopecia totalis, and several other autoimmune conditions. Medscape Medical News source https://www.medscape.com/viewarticle/997134?src=rss

Pfizer, BioNTech and biotech firm Promosome have agreed to end Promosome's lawsuit accusing the COVID-19 vaccine makers of infringing a patent related to messenger RNA technology. Reuters Health Information source https://www.medscape.com/s/viewarticle/997111?src=rss

The Brazilian Federal Council of Medicine recently published the results of a survey intended to improve understanding of who the country's doctors with disabilities are and where they are based. Medscape Medical News source https://www.medscape.com/viewarticle/997107?src=rss

Nearly 90% of NCCN member institutions that responded to a September survey reported a shortage of at least one anticancer agent. Medscape Medical News source https://www.medscape.com/viewarticle/997103?src=rss

The international group behind the new terminology worked for 3 years to build a consensus, but convincing their peers to adopt it will require more effort. Medscape Medical News source https://www.medscape.com/viewarticle/997101?src=rss

Stereotactic radiosurgery was better at preventing loss of verbal recall function at 3 months than whole-brain radiation therapy, the current standard of care for patients with brain metastases from small cell lung cancer. Medscape Medical News source https://www.medscape.com/viewarticle/997080?src=rss

For patients with low and favorable intermediate-risk prostate cancer, stereotactic body radiation therapy delivered in five fractions provided similar 5-year disease control as conventional, higher-dose external-beam radiation. Medscape Medical News source https://www.medscape.com/viewarticle/997078?src=rss

The anti-androgenic agent is used to treat HS in women, but there is a paucity of data on its efficacy and whether certain patient characteristics influence response. MDedge News source https://www.medscape.com/s/viewarticle/997074?src=rss

The FDA said on Tuesday it authorized an updated version of Novavax's COVID-19 vaccine for emergency use in individuals aged 12 years and older. Reuters Health Information source https://www.medscape.com/s/viewarticle/997056?src=rss

A chemoimmunotherapy and radiation combination without autologous stem cell transplant produced high response rates in children and young adults with low-risk relapsed/refractory Hodgkin lymphoma. Medscape Medical News source https://www.medscape.com/viewarticle/997044?src=rss

More physicians are using AI chatbots in their practices to help with diagnostic and decision support. Here's how to get the best results. Medscape Medical News source https://www.medscape.com/viewarticle/997040?src=rss

Clinicians described several strategies for treating osteoporosis while acknowledging that commonly used quality assessments need work. Medscape Medical News source https://www.medscape.com/viewarticle/997037?src=rss

Bad behavior abounds on social media, even by physicians. Doctors discuss the boundaries they maintain when posting on various platforms and offer tips on keeping content professional. Medscape Medical News source https://www.medscape.com/viewarticle/996283?src=rss

Lower risk of bacteremia in children with sickle cell disease (SCD) presenting to the emergency department (ED) with fever calls critical reexamination of long standing approach towards management of SCD in children. Medscape Medical News source https://www.medscape.com/viewarticle/rethinking-approach-manage-fever-ed-children-sickle-cell-2023a1000o23?src=rss

Women randomly assigned to metformin at diagnosis had improved blood glucose levels compared with placebo and were less likely to need insulin, but questions remain. Medscape Medical News source https://www.medscape.com/viewarticle/997027?src=rss

Balfaxar helps restore blood coagulation by replenishing the levels of clotting factors. Medscape Medical News source https://www.medscape.com/viewarticle/fda-greenlights-balfaxar-warfarin-reversal-urgent-surgery-2023a1000m41?src=rss

Scientists who pioneered an underlying technology to harness fragile genetic material in a way that ultimately resulted in the mRNA vaccines used to combat the COVID-19 pandemic were honored Monday. Medscape Medical News source https://www.medscape.com/viewarticle/997002?src=rss

Shares of Structure Therapeutics soared on Friday as early data from the drug developer's oral obesity treatment exceeded analysts' expectations. Reuters Health Information source https://www.medscape.com/s/viewarticle/996950?src=rss

Observational data suggest that menstruation can alter A1c readings and that the cut-off value for diagnosis of type 2 diabetes might be too high in women under 50 years. Medscape Medical News source https://www.medscape.com/viewarticle/996986?src=rss

A retrospective study found significantly higher rates of hyperglycemia among patients with metastatic breast cancer treated with alpelisib in clinical practice compared with clinical trials. Medscape Medical News source https://www.medscape.com/viewarticle/996985?src=rss

AbbVie has said a late-stage study of its experimental combination therapy failed to meaningfully increase the survival rate of patients without the disease worsening. Reuters Health Information source https://www.medscape.com/s/viewarticle/996945?src=rss

Making some money-related changes before 2024 could make a big difference when it comes to your tax bite or your refund come April. Medscape Medical News source https://www.medscape.com/viewarticle/996547?src=rss

Most patients who experienced sentinel central events during drug-induced sleep endoscopy (DISE) then transitioned to obstruction in approximately 12 minutes. Medscape Medical News source https://www.medscape.com/viewarticle/996979?src=rss