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Showing posts from May, 2023

Abortion Limits: Less Evidence-Based Care for Miscarriages

The results revealed that "abortion restrictions have far-reaching effects on early pregnancy loss care and on resident education." MDedge News source https://www.medscape.com/viewarticle/992598?src=rss

Intensive BP Reduction After Stroke Recanalization Harmful

Intensive blood pressure management worsens outcomes and should not be pursued in stroke patients successfully recanalized with intra-arterial thrombectomy, results of the OPTIMAL-BP trial show. Medscape Medical News source https://www.medscape.com/viewarticle/992589?src=rss

Enthesitis Linked to Dupilumab Use for Atopic Dermatitis

Musculoskeletal symptoms identified in some patients treated with dupilumab for atopic dermatitis could help further understanding of how enthesitis develops. Medscape Medical News source https://www.medscape.com/viewarticle/992587?src=rss

Using 'Green' Buses Could Up School Attendance

Switching to greener, cleaner, and more reliable buses may cut down on student absences. Quick Take source https://www.medscape.com/viewarticle/992579?src=rss

Posluma Approved for PET Imaging in Prostate Cancer

Flotufolastat fluorine-18 (Posluma), a new PSMA-targeted PET radiopharmaceutical, has been approved in the US for use in prostate cancer. Medscape Medical News source https://www.medscape.com/viewarticle/992577?src=rss

Endoscopists Outperform CADx in Predicting Polyp Histology

Study findings suggest CADx remains a potentially useful aid in polyp diagnosis, but additional training is needed to improve accuracy in less than ideal conditions. Medscape Medical News source https://www.medscape.com/viewarticle/992575?src=rss

IV vs Intranasal Ketamine: Which is Best?

There is no difference in the efficacy of IV ketamine and its intranasal counterpart for treatment-resistant depression, but cost and the speed of effect may be the factors that determine treatment choice. Medscape Medical News source https://www.medscape.com/viewarticle/992558?src=rss

APA Launches Online Eating Disorder Assessment Tool

A new online tool helps clinicians screen for, and treat, patients' eating disorders on the basis of recently released APA guidelines. Medscape Medical News source https://www.medscape.com/viewarticle/992559?src=rss

People Still Want Their Medical Intelligence in Human Form

Well, we've got some good news for the physicians out there, and we've got some bad news. MDedge News source https://www.medscape.com/viewarticle/992557?src=rss

Counseling parents about the leading cause of death in U.S. children: guns

A former colleague of mine maintained throughout his career that the most logical way for family physicians to provide preventive services for adults was to focus on the most common causes of death. Although the top diagnoses leading to death recorded by the Centers for Disease Control and Prevention in 2021 were heart disease, cancer, and COVID-19, that’s not what he meant. Instead, he was speaking of the “ actual causes of death ,” or the behavioral causes of the causes, which from 1990 to 2017 were tobacco use, poor diets, and physical inactivity . Clinicians can have the largest effect on preventing death in adults by counseling patients to stop smoking, eat healthier foods, and exercise. What about children and adolescents? All-cause mortality in Americans aged 1 to 19 years has been increasing since 2019 , partially due to COVID-19 but mostly from a rise in fatal injuries that began prior to the pandemic. Motor vehicle accidents, which have long been the top cause of death in

Kids Think Alexa Is Smarter Than Roomba

Children aged 4 to 11 years say they think Alexa is smarter than Roomba but that you should be nice to both. Quick Take source https://www.medscape.com/viewarticle/992536?src=rss

PTSD, Anxiety Linked to Out-of-Hospital Cardiac Arrest

A new study shows an association between stress-related disorders like PTSD as well as anxiety and an increased risk of out-of-hospital cardiac arrest. Medscape Medical News source https://www.medscape.com/viewarticle/992535?src=rss

Cardiopathy No Basis for Choosing Anticoagulation in ESUS

Clinicians shouldn't expect apixaban to offer benefit over aspirin in patients with embolic stroke of undetermined source simply because they have atrial cardiopathy, ARCADIA investigators conclude. Medscape Medical News source https://www.medscape.com/viewarticle/992525?src=rss

No Added Benefit From Revascularization in Low-Risk CAS

Optimized medical therapy may be enough in patients with carotid artery stenosis who have a low to intermediate stroke risk, after the ESCT-2 trial showed no benefit from adding revascularization. Medscape Medical News source https://www.medscape.com/viewarticle/992524?src=rss

Lomitapide Shows Promise in Pediatric Homozygous FH

Children and adolescents with homozygous familial hypercholesterolemia could benefit from lomitapide therapy, suggests a trial, although safety concerns and upcoming novel drugs question its place. Medscape Medical News source https://www.medscape.com/viewarticle/992523?src=rss

Vulvodynia: A Little-Known and Treatable Condition

Patients who present with this problem should be treated with empathy and referred to a specialist, according to a gynecologist. Medscape Medical News source https://www.medscape.com/viewarticle/992499?src=rss

Can a Saliva Test Predict the Best Way to Manage Obesity?

It sounds like a simple solution to a complicated problem: Find out what kind of obesity you have based on a one-time genetic saliva test to get a better idea of what treatments might work. WebMD Health News source https://www.medscape.com/viewarticle/992497?src=rss

Healthy Microbiota Emerges as a Strong Ally Against Disease

At a recent conference, researchers shared knowledge about changes in the microorganisms residing in our bodies, as well as about the many common diseases in which these microorganisms are involved. Medscape Medical News source https://www.medscape.com/viewarticle/992501?src=rss

Gastroenterologists Among the Top Five Earners: Report

Gastroenterologists made 11% more in 2022 than 2021, and most continue to enjoy their work and would pick gastroenterology again. Medscape Medical News source https://www.medscape.com/viewarticle/992480?src=rss

Music Therapy Helps Motivate Patients With Schizophrenia

In addition to reducing negative symptoms of schizophrenia, music therapy improves sleep and symptoms of depression. Medscape Medical News source https://www.medscape.com/viewarticle/992478?src=rss

Don't Remove Bladder for Localized Muscle-Invasive Cancer

Investigators say bladder-preserving treatment should be offered to all patients, not just poor surgical candidates. Medscape Medical News source https://www.medscape.com/viewarticle/992476?src=rss

AD in Infancy: Diagnostic Advice and Treatment Tips

Diagnosis requires careful consideration of mimicking conditions and a broader list of differential diagnoses in those infants with poor growth or frequent infections, Dr. Elaine Siegfried said. MDedge News source https://www.medscape.com/viewarticle/992450?src=rss

Care Bundle Improves Outcome in ICH: INTERACT3

A combination of simple interventions for patients with acute hemorrhagic stroke has been shown to significantly improve the chances of survival without major disability. Medscape Medical News source https://www.medscape.com/viewarticle/992449?src=rss

Pregnancies With Sjögren's Are Largely Safe

There was no difference in risk of adverse pregnancy outcomes between women with Sjögren's and the control group, but negative outcomes were more frequent with antiphospholipid antibodies. Medscape Medical News source https://www.medscape.com/viewarticle/992447?src=rss

Closing the Gender Pay Gap in Primary Care

Women physicians' pay inequity is ongoing despite decades of research and talk about narrowing the gap. Is there progress toward closing it? Medscape Medical News source https://www.medscape.com/viewarticle/992444?src=rss

Treatment of Depression Reduces Cardiovascular Risk

Data underscore the importance of facilitating access to psychotherapists to promote mental and physical health, a researcher said. Medscape Medical News source https://www.medscape.com/viewarticle/992433?src=rss

Diabetes, Cholesterol Meds Use Drops After Bariatric Surgery

Use of lipid and diabetes medications are lower 15 years after bariatric surgery, compared with patients with obesity who didn't undergo such surgery, in a large population-based study. Medscape Medical News source https://www.medscape.com/viewarticle/992424?src=rss

Younger Age of Type 2 Diabetes Onset Link to Dementia Risk

Data also suggest that increased risk for dementia among people with prediabetes is limited to those who subsequently develop type 2 diabetes. Medscape Medical News source https://www.medscape.com/viewarticle/992420?src=rss

Once-Daily Nifedipine Sufficient for Pregnancy Hypertension

A single 30-mg daily dose of nifedipine appeared similarly effective as 60 mg taken in two daily doses for treating hypertensive disorders in pregnancy, a new study found. MDedge News source https://www.medscape.com/viewarticle/992403?src=rss

Women at Higher Risk for Inflation-Related Stress

New findings indicate which groups are more likely to have inflation-related stress but do not clarify the relationship between this stress and disparities in health outcomes. Medscape Medical News source https://www.medscape.com/viewarticle/992402?src=rss

Half of Deaths From Homozygous FH Occur Before Age 32 Years

The median age of death from homozygous familial hypercholesterolemia is just 32 years, with many patients having had poor lipid control, shows registry data described by one expert as "terrifying." Medscape Medical News source https://www.medscape.com/viewarticle/992391?src=rss

Breast Cancer Survivors Need Comprehensive Care Plans

Several studies suggest that many breast cancer patients are not well prepared to move forward after a breast cancer diagnosis and subsequent treatments. MDedge News source https://www.medscape.com/viewarticle/992392?src=rss

CKD Screening in All Adults Found Cost-Effective

The new evidence follows the release earlier this year of a draft research plan to reassess the potential role for such screening in asymptomatic adults in the United States. MDedge News source https://www.medscape.com/viewarticle/992390?src=rss

Doc Accused of Impairment Wins $3.7M for Unproven Complaint

A jury decided in favor of a family doctor who says his life was upended after an unproven impairment allegation was mishandled by a Kentucky hospital. Read how the case affected his career. Medscape Medical News source https://www.medscape.com/viewarticle/992386?src=rss

Standard Measure May Underestimate OSA in Black Patients

Data from a secondary analysis showed a smaller decrease in oxygen saturation in Black patients compared with White patients with OSA. Medscape Medical News source https://www.medscape.com/viewarticle/992387?src=rss

Serious Mental Illness Not a Factor in Most Mass School Shootings

Most mass school shooters do not have a history of psychosis or other serious mental illness, yet are clearly struggling psychologically, new research suggests. Medscape Medical News source https://www.medscape.com/viewarticle/992382?src=rss

Common Fracture Predictors Often Fall Short

Race does not predict osteoporosis risk, researchers found, as clinicians noted that many people with osteoporosis go unidentified. Medscape Medical News source https://www.medscape.com/viewarticle/992335?src=rss

FDA Approves New Indication for Avapritinib

Avapritinib (AYVAKIT) is now approved to treat adults with indolent systemic mastocytosis. Medscape Medical News source https://www.medscape.com/viewarticle/992323?src=rss

Half of Americans Aren't As 'Green' As They Claim To Be

More than half of Americans are guilty of 'greenwashing' their environmental status and exaggerate what they do to help the planet. Quick Take source https://www.medscape.com/viewarticle/992321?src=rss

Junior Doctors in England Plan More Strikes

Junior doctors in England plan to stage more strikes in June, their union said, meaning more strain for the state-run health service, NHS, after pay negotiations with the government collapsed on Monday without a resolution. Reuters Health Information source https://www.medscape.com/viewarticle/992283?src=rss

Biggest Cancer Meeting Is Back in Full Swing: ASCO 2023

The annual meeting of the American Society of Clinical Oncology (ASCO) will be bustling with 40,000 in-person attendees. Partnering with patients will be the core theme this year. Medscape Medical News source https://www.medscape.com/viewarticle/992320?src=rss

ChatGPT Bot Flunks Gastroenterology Exam

The AI language-processing model scored below the minimum passing grade of 70% on a self-assessment test and is not recommended for medical education. Medscape Medical News source https://www.medscape.com/viewarticle/992318?src=rss

Envision Files for Chapter 11 Bankruptcy, Plans Layoffs

The massive physician staffing company has faced numerous pressures, including doctor shortages, pandemic-driven patient volume declines, inflation, and federal and state balance billing laws. Medscape Medical News source https://www.medscape.com/viewarticle/992281?src=rss

FDA Approves Autoinjector Pen for Humira Biosimilar, Cyltezo

The drug will be commercially available on July 1, 2023. Medscape Medical News source https://www.medscape.com/viewarticle/992277?src=rss

Scheduled Bleeding Boosts Tolerability of Hormone Implants

After taking norethindrone acetate for 1 week every 4 weeks, 80% of participants reported satisfactory bleeding patterns with etonogestrel implants in a new study. Medscape Medical News source https://www.medscape.com/viewarticle/992275?src=rss

Which Interventions Could Lessen the Burden of Dementia?

A team from the University of Bordeaux in France modeled the impact of interventions targeting three main vascular risk factors for dementia. Medscape Medical News source https://www.medscape.com/viewarticle/992273?src=rss

Dupilumab Curbs Acute COPD Exacerbations

Patients treated with dupilumab for COPD also showed significant improvements in lung function at 12 and 52 weeks. Medscape Medical News source https://www.medscape.com/viewarticle/992271?src=rss

Marijuana Linked to Higher PAD Risk

A large study found marijuana users had almost four times the risk of peripheral artery disease, but no higher risk of death or coronary intervention. MDedge News source https://www.medscape.com/viewarticle/992260?src=rss

Endometrial Cancer Recurrence Linked to Beta-Catenin Levels

Abnormal expression of beta-catenin is a risk factor for vaginal recurrence of endometrial cancer, but it can be prevented with adjuvant radiation, a team from Stanford University reports. Medscape Medical News source https://www.medscape.com/viewarticle/992257?src=rss

Tofacitinib De-escalation in UC: Proceed With Caution

Patients with ulcerative colitis who de-escalate tofacitinib therapy may experience a disease flare, and not all will recapture clinical response with dose re-escalation, real-world data show. Medscape Medical News source https://www.medscape.com/viewarticle/992245?src=rss

AMA President on Fighting Prior Auth, Scope Creep, and More

The president of the American Medical Association, Jack Resneck Jr, MD, discusses government interference in healthcare, the prior authorization mess, and more in a wide-ranging interview with Medscape. Medscape Medical News source https://www.medscape.com/viewarticle/992222?src=rss

FDA Clears iLet Bionic Pancreas Insulin Delivery System

The FDA has cleared a next-generation insulin pump and software combination that provides greater automation than current "artificial pancreas" systems. FDA Approvals source https://www.medscape.com/viewarticle/992221?src=rss

Well-Funded Anti-Poverty Programs Protect Kids' Brains

Poverty has an adverse effect on the developing brains of kids. This study found less of an impact on kids who live in states with generous anti-poverty programs. Medscape Medical News source https://www.medscape.com/viewarticle/992210?src=rss

Ear Acupuncture With Diet Aids Weight Loss

Ear acupuncture with beads rather than needles, when combined with reduced food intake, leads to weight loss and a reduction in waist circumference, in Japanese men. Medscape Medical News source https://www.medscape.com/viewarticle/992202?src=rss

Better Survival After MIS for Advanced Ovarian Cancer

A large, propensity-matched review found that survival was better with fewer complications when women with advanced ovarian cancer underwent minimally invasive debulking surgery instead of open surgery. Medscape Medical News source https://www.medscape.com/viewarticle/992200?src=rss

What's the matter with corporate primary care?

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I've been meaning to write about this topic for a while, but Dr. Josh Freeman at Medicine and Social Justice beat me to it last week. Josh is a fellow blogger, retired family physician, and Chair emeritus of the Department of Family Medicine at the University of Kansas. His latest post, " Private equity, private profit, Medicare and your health: They are incompatible ," explored in depth the negative effects of private equity and for-profit corporations buying up subspecialty and primary care practices, also discussed in a KFF Health News article and in the New York Times . Put simply, the goal of those purchases is to turn a quick profit - often by "upcoding" to charge more for visits and procedures and slashing critical support staff - rather than to serve the best interests of patients and clinicians. Part of the corporate rush to invest aggressively in primary care is the unintended consequence of privatizing Medicare and moving away from the fee-for-ser

DLBCL: Major New Treatment Breakthroughs

Recent significant breakthroughs for diffuse large B-cell lymphoma (DLBCL) have come through the use of CAR T-cell and immunotherapies and the FDA approval of polatuzumab for frontline DLBCL. MDedge News source https://www.medscape.com/viewarticle/992149?src=rss

Teach Basic Lifesaving Skills Starting Age 4, AHA Advises

Teaching young children basic life support training has the potential to educate whole generations to respond to cardiac arrest and increase survival of out-of-hospital cardiac arrest. Medscape Medical News source https://www.medscape.com/viewarticle/992148?src=rss

Misdiagnosis Still Common in Pancreatic Cystic Neoplasms

A new study suggests that with better diagnosis a significant proportion of patients with pancreatic cystic neoplasms could be spared from surgery. MDedge News source https://www.medscape.com/viewarticle/992141?src=rss

Limit PSA Screening to Men With Symptoms

A new strategy that would limit screening for prostate cancer to men under 70 who are at risk or symptomatic would reduce the potential harm from overdiagnosis and overtreatment, an international panel recommends. Medscape Medical News source https://www.medscape.com/viewarticle/992137?src=rss

Analysis: 40% of Info About Cirrhosis on TikTok Is Incorrect

Study presented at DDW finds that patient-derived sources are usually trustworthy, but promotional sources are often misleading. MDedge News source https://www.medscape.com/viewarticle/992140?src=rss

Unveiling Sexual Dysfunction: Clinicians Can Do More

Nearly half of all women experience some sort of sexual dysfunction. Clinicians should be comfortable speaking with patients about their sexual health. Medscape Medical News source https://www.medscape.com/viewarticle/992105?src=rss

Unhealthy Foods Marketed to Children Prevalent in Canada

Foods in child-appealing packages that include graphic designs, colors, games, and other engaging characteristics were higher in sugar and sodium than foods in nonappealing packaging. Medscape Medical News source https://www.medscape.com/viewarticle/992103?src=rss

COVID Emergency Over, but Hundreds Are Still Dying Weekly

Just 6 months after President Joe Biden declared that the pandemic is over, Debbie's death was a painful reminder to Traci and her family that COVID hasn't actually gone anywhere. WebMD Health News source https://www.medscape.com/viewarticle/992093?src=rss

Prior Auth Has Radiation Onc Deferring to Business Manager

One radiation oncologist reflects on an odd, stressful element of prior authorization: the need to ask his business manager what he's allowed to do. Medscape Medical News source https://www.medscape.com/viewarticle/992090?src=rss

CDC Warns of Mpox Resurgence This Summer

"The outbreak is not over," the CDC alert stated, noting that springtime and summertime gatherings and festivals could lead to renewed virus spread. WebMD Health News source https://www.medscape.com/viewarticle/992082?src=rss

Prophylactic Abx Not Supported in Severe Alcoholic Hepatitis

Adding a prophylactic antibiotic to corticosteroid therapy does not improve survival in severe alcohol-related hepatitis and should be reserved for patients with active infection. Medscape Medical News source https://www.medscape.com/viewarticle/992069?src=rss

Heart Failure With Preserved EF: More Respect for Exercise?

The most common form of heart failure in older adults can be challenging to manage. An update at AGS addressed diagnosis, medications, inequities, and the role of exercise. Medscape Medical News source https://www.medscape.com/viewarticle/992037?src=rss

How BMI Over Time Impacts GI Cancer Risk

New data suggest that higher body mass index and changes in BMI may increase risk for gastrointestinal cancer. Medscape Medical News source https://www.medscape.com/viewarticle/992031?src=rss

Novel Insights on Takotsubo Could Lead to New Therapies

New mechanisms underlying this condition, often dubbed "broken heart syndrome," have been suggested from hemodynamic studies, which could lead to new treatment strategies. Medscape Medical News source https://www.medscape.com/viewarticle/992016?src=rss

Air Pollution Is a Fatal Threat to Children in Europe

The European Environment Agency recently reviewed the effects of air pollution on children's health and outlined measures for reducing their exposure to it. Medscape Medical News source https://www.medscape.com/viewarticle/992011?src=rss

New Trials in Breast Cancer: Could Your Patient Benefit?

Perhaps one of your patients is eligible to join a clinical trial currently recruiting people with breast cancer. Medscape Medical News source https://www.medscape.com/viewarticle/992006?src=rss

New HER2 Drug for Breast Cancer Stalled by FDA

The FDA said it needs more data the new antibody-drug conjugate (ADC) trastuzumab duocarmazine for use in advanced or metastatic breast cancer. Medscape Medical News source https://www.medscape.com/viewarticle/992001?src=rss

High BMI Impacts DFS in Younger Patients With Breast Cancer

In postmenopausal women with hormone receptor–positive breast cancer, overweight and obesity were overall predictors of lower disease-free survival. MDedge News source https://www.medscape.com/viewarticle/991938?src=rss

Palliative Care for Major Nonpalliative Cancer Surgery?

A randomized controlled trial questions the value of routine perioperative palliative care consultation in patients with cancer undergoing major curative-intent surgery. Medscape Medical News source https://www.medscape.com/viewarticle/991935?src=rss

Cervical Cancer Screenings Double With Mailed DIY Kits

Mailing do-it-yourself sampling kits to test for cervical cancer doubled the rate of screening in a population of low-income and under-screened women, researchers say. WebMD Health News source https://www.medscape.com/viewarticle/991936?src=rss

Hagop Kantarjian, MD, Honored by ASCO for Leukemia Research

Kantarjian receives the highest honor from the American Society of Clinical Oncology (ASCO) for his lifelong contributions to leukemia research and patient care. Medscape Medical News source https://www.medscape.com/viewarticle/991927?src=rss

PDAC Surveillance in High-Risk Cases Improves Outcomes

A propensity-matched analysis found a benefit even after considering lead-time bias, suggesting a real benefit. MDedge News source https://www.medscape.com/viewarticle/991920?src=rss

AGA Update Provides Guidance on Extraesophageal GERD

Extraesophageal reflux symptoms are a subset of gastroesophageal reflux disease that can be difficult to diagnose. MDedge News source https://www.medscape.com/viewarticle/991918?src=rss

As COVID Emergency Ends, Mail Access to Cancer Meds at Risk

Now that the Public Health Emergency has ended, a CMS regulation known as the Stark law prohibits independent practices from shipping oral and injectable therapeutics to Medicare patients by mail. Medscape Medical News source https://www.medscape.com/viewarticle/991895?src=rss

Etrasimod Looks Safe for Ulcerative Colitis Out to 2.5 Years

Experts recommend an electrocardiogram to screen for some heart-related risks before prescribing. Medscape Medical News source https://www.medscape.com/viewarticle/991893?src=rss

From Burned Out Oncologist to Published Novelist

Jennifer Lycette, MD, discusses her new book on an AI-dominated future and what motivated her to write it. Medscape Medical News source https://www.medscape.com/viewarticle/991889?src=rss

Normal Vitamin D Level May Up Anti-PD-1 Response in Melanoma

Responses to immunotherapy were better in patients with normal levels of vitamin D, including in those who achieved normal levels via supplementation. Medscape Medical News source https://www.medscape.com/viewarticle/991888?src=rss

IVIG Shows No Impact on VTE Risk in Dermatomyositis Patients

The rate of venous thromboembolism did not increase in dermatomyositis patients treated with intravenous immunoglobulin, compared with those not treated with IVIG. MDedge News source https://www.medscape.com/viewarticle/991881?src=rss

CGM Completes Picture of A1c in Type 2 Diabetes

'It is hoped that the use of these new [CGM] metrics should lead to an improved quality of glycemic control and, in turn, to a reduction in the number of diabetes-related complications,' say researchers. Medscape Medical News source https://www.medscape.com/viewarticle/991877?src=rss

Cancer Survivors With Functional Limitations Have Doubled

The number of cancer survivors who report functional limitation has more than doubled in 20 years, according to a research letter published in JAMA Oncology. MDedge News source https://www.medscape.com/viewarticle/991878?src=rss

Simplifying Diagnosis of Rejection After Kidney Transplant

User-friendly ChatGPT-like system allows for accurate diagnoses of rejection, using often complicated Banff classification criteria 'with just a few clicks.' Observers hail the work as 'innovative.' Medscape Medical News source https://www.medscape.com/viewarticle/991824?src=rss

Deep Sleep May Mitigate the Impact of Alzheimer's Pathology

Deep sleep may help protect cognitive reserve, acting as a buffer against Alzheimer's disease pathology. Medscape Medical News source https://www.medscape.com/viewarticle/991825?src=rss

Here's How We Can Rebuild Trust in Vaccines

Falling rates of childhood vaccination and declining support for school vaccination laws have some experts exploring new ways to boost childhood vaccination rates. Medscape Medical News source https://www.medscape.com/viewarticle/991820?src=rss

Rheumatoid Arthritis Linked to Increased Parkinson's Risk

A large prospective study shows that RA is linked to a twofold increased risk for Parkinson's disease, in new findings that suggest motor symptoms in this population should be thoroughly investigated by a neurologist. Medscape Medical News source https://www.medscape.com/viewarticle/991819?src=rss

Altria Agrees to Settlement to Resolve Juul-Related Cases

Altria Group said it will pay $235 million to settle at least 6000 lawsuits accusing it of fueling a teen vaping epidemic through its former investment in e-cigarette maker Juul Labs. Reuters Health Information source https://www.medscape.com/viewarticle/991803?src=rss

Insulin Makers Testify on Capitol Hill Over Prices

Leaders of major insulin makers and pharmacy benefit managers traded blame for the life-saving drug's high price while testifying at a US Senate committee hearing. Reuters Health Information source https://www.medscape.com/viewarticle/991770?src=rss

Risk Assessment First Urged for Fragility Fracture Screening

A new Canadian guideline recommends a risk assessment–first approach to fragility fracture screening before a bone mineral density test to facilitate shared decision-making. Medscape Medical News source https://www.medscape.com/viewarticle/991814?src=rss

Clot Evacuation After ICH Tied to Better Outcome: ENRICH

ENRICH trial results comparing minimally invasive trans-sulcal parafascicular surgery (MIPS) to standard care are encouraging but need replication in a larger trial, one outside expert says. Medscape Medical News source https://www.medscape.com/viewarticle/991805?src=rss

Doctor Spots a Gunshot Victim Staggering Down His Street

While making coffee just after rolling out of bed, this MD sees a gunshot victim right outside his front window and must intervene before the man bleeds out. Medscape Medical News source https://www.medscape.com/viewarticle/991777?src=rss

Nursing Pipeline Jams With International Visa Cap on Nurses

A federal visa retrogression prevents hospitals from hiring international workers with associate degrees as entry-level nurses to fill positions during a national nursing shortage. Medscape Medical News source https://www.medscape.com/viewarticle/991774?src=rss

Mohs Surgery Improves Survival in Early-Stage Merkel Cell

Compared with conventional surgery, the use of Mohs significantly improved survival among patients with Merkel cell carcinoma. Medscape Medical News source https://www.medscape.com/viewarticle/991739?src=rss

FDA Expands Use of Dapagliflozin to Broader Range of HF

The SGLT2 inhibitor is now indicated for treatment of heart failure across the full spectrum of left-ventricular ejection fraction ― including HF with mildly reduced and preserved ejection fraction. Medscape Medical News source https://www.medscape.com/viewarticle/991736?src=rss

Updated immunization and screening recommendations aim to eradicate hepatitis B

In November 2021, the Centers for Disease Control and Prevention (CDC)’s Advisory Committee on Immunization Practices (ACIP) replaced risk factor-based eligibility in adults with a recommendation for universal hepatitis B vaccination in persons aged 19 to 59 years. The ACIP noted that despite routine administration of hepatitis B vaccine in infancy, as of 2018 only 30% of U.S. adults had received the full vaccine series, and one half of acute hepatitis B cases occurred in persons aged 30 to 49 years. A national survey of family physicians in February 2022 found that more than half of respondents were not aware of the updated guidelines, and only 8% had fully implemented them. Gaps in screening and treatment also put patients at greater risk of developing chronic hepatitis B and its complications. An analysis of insurance claims data from 2015 to 2020 found that even though all pregnant patients should be screened for hepatitis B at their first prenatal visit to prevent perinatal

Part-Time Physician: Is It a Viable Career Choice?

There may be many solutions for overstressed, burned out, and overworked physicians. Perhaps going part-time is one of them; but there are also negatives to consider. Medscape Medical News source https://www.medscape.com/viewarticle/991730?src=rss

Metformin Ups Myocardial Perfusion and Survival in T2D

Treatment of adults with type 2 diabetes with metformin significantly linked with better myocardial perfusion and improved survival in a multicenter, observational study with 572 subjects. First Look source https://www.medscape.com/viewarticle/991732?src=rss

CRC Screening Rates Are Higher in Medicaid Expansion States

Medicaid expansion may be a determinant of whether screening is even offered. MDedge News source https://www.medscape.com/viewarticle/991726?src=rss

Olanzapine Effective for Higher-Risk Chemo-Induced Nausea

The antipsychotic improves on standard antiemetic therapy in patients known to be more prone to nausea and vomiting with chemotherapy. Medscape Medical News source https://www.medscape.com/viewarticle/991693?src=rss

Phase 3 Trial: Maribavir Yields Post-Transplant Benefits

Maribavir may reduce mortality risk among patients with resistant or refractory post-transplant CMV infection following hematopoietic stem cell and solid organ transplant. MDedge News source https://www.medscape.com/viewarticle/991692?src=rss

High Follistatin Predicts Poor Cardiometabolic Outcomes

Elevated plasma levels of the liver protein follistatin may predict incident chronic kidney disease and other adverse outcomes, independent of diabetes, based on 23-year follow-up of a Swedish cohort. First Look source https://www.medscape.com/viewarticle/991683?src=rss

At-Home Monitoring Device Can Predict Crohn's Disease Flares

A device that remotely monitors the sleep patterns, breathing, and gait of people with Crohn's disease can identify increased disease activity prior to it being clinically evident, say researchers. Medscape Medical News source https://www.medscape.com/viewarticle/991682?src=rss

CDC Says Walensky Will Step Down as Director in June

CDC Director Rochelle Walensky, MD, MPH, will step down from her position at the end of June, 2½ years after assuming the role during the height of the COVID-19 pandemic. WebMD Health News source https://www.medscape.com/viewarticle/991677?src=rss

Clinic to Pay $19 Mil to Family of Misdiagnosed Newborn

A Wisconsin health system must pay millions to the family of a newborn baby for failing to diagnose meningitis. Medscape Business of Medicine source https://www.medscape.com/viewarticle/991596?src=rss

Virtual Care Not Linked With Greater ED Use During Pandemic

A recent analysis found an inverse relationship between patients' emergency department use and physicians' use of telemedicine. Medscape Medical News source https://www.medscape.com/viewarticle/991642?src=rss

WHO Officially Calls End to Global COVID-19 Health Emergency

Not much is expected to change in a realistic sense, and the declaration doesn't mean COVID is no longer with us. WebMD Health News source https://www.medscape.com/viewarticle/991632?src=rss

New AACE Type 2 Diabetes Algorithm Individualizes Care

Consensus statement summarizes recent guidelines, with separate graphics for complications- and glucose-centric care and weight loss medications, plus information about cost and access. Medscape Medical News source https://www.medscape.com/viewarticle/991628?src=rss

LAA Closure Outcomes Improve With CCTA: Swiss-Apero Subanalysis

A trial of left atrial appendage closure reported better outcomes with preprocedure computed tomography than transesophageal echocardiography alone. MDedge News source https://www.medscape.com/viewarticle/991623?src=rss

Oral Weight-Loss Drug Will Have Similar Efficacy as Wegovy

Novo Nordisk expects the oral version of its semaglutide drug to treat obesity to have similar efficacy as its Wegovy injection, a senior executive said on Thursday. Reuters Health Information source https://www.medscape.com/viewarticle/991558?src=rss

Novel Levodopa Delivery System Promises Continuous Dosing

Called DopaFuse, the experimental device is designed to deliver the levodopa and carbidopa into the mouth through a micropump within a wearable retainer. MDedge News source https://www.medscape.com/viewarticle/991566?src=rss

Better Access to TAVR Associated With Improved Outcomes

A study that included patients in Ontario and New York State suggests that earlier intervention may explain differences in outcomes. Medscape Medical News source https://www.medscape.com/viewarticle/991573?src=rss

Normal CRP During RA Flares May Describe Unique Phenotype

In about 5% of patients with seropositive RA, C-reactive protein levels were normal despite disease flares during a 5-year period. The findings represent an "underappreciated, persistent phenotype." Medscape Medical News source https://www.medscape.com/viewarticle/991571?src=rss

Survey Reveals Teen Substance Use Screening Inadequate

Current screening rates and practices among primary care pediatricians in the United States are unknown. MDedge News source https://www.medscape.com/viewarticle/991570?src=rss

Nurses Push for State, Federal Laws Setting Staffing Levels

Despite nursing union support for a federal bill setting minimum nurse-to-patient ratios, some hospital groups have their doubts. Meanwhile, state legislative efforts continue. Medscape Medical News source https://www.medscape.com/viewarticle/991559?src=rss

Cortisol From Adrenal Masses Linked With Dysglycemia

People with type 2 diabetes and a cortisol-secreting adrenal mass had worse glycemic control compared with those with type 2 diabetes and a nonfunctioning adrenal mass. First Look source https://www.medscape.com/viewarticle/991563?src=rss

Having Plants Can Help Prevent Colds

Plants don't just clean air; they may protect us from colds, COVID, and other viral and bacterial diseases. Quick Take source https://www.medscape.com/viewarticle/991554?src=rss

Ozempic: Cost, Coupons, and Ways to Save Cash

A box or one pen, which could last 30 days, can cost nearly $1200, depending on the pharmacy. WebMD Health News source https://www.medscape.com/viewarticle/991528?src=rss

Bariatric Surgery May Reverse Peripheral Neuropathy

Bariatric surgery may enable peripheral nerve regeneration, making it an effective treatment for individuals with obesity at risk of diabetes and peripheral neuropathy, says a researcher. Medscape Medical News source https://www.medscape.com/viewarticle/991526?src=rss

FDA Approves First RSV Vaccine for Older Adults

This is the first approved RSV vaccine in the United States, and the world’s first vaccine for older adults. Medscape Medical News source https://www.medscape.com/viewarticle/991527?src=rss

Vanda Sues US Government Over Drug Trade Secrets

The company has sued the federal government over accusations that the FDA passed trade secrets about its schizophrenia drug Fanapt and sleep-disorder medication Hetlioz to generic competitors. Reuters Health Information source https://www.medscape.com/viewarticle/991500?src=rss

Stroke Prevalence Stable in US Over Past 20 Years

The prevalence of stroke in community-dwelling individuals has remained stable in the US between 1999 and 2018, new figures show. Medscape Medical News source https://www.medscape.com/viewarticle/991516?src=rss

Long-COVID Rate May Be Higher With Rheumatic Diseases

The results highlight the need for close monitoring and optimized multidisciplinary care for long-term adverse events after COVID-19 in patients with rheumatic disease. Medscape Medical News source https://www.medscape.com/viewarticle/991466?src=rss

FDA OKs Once-Nightly Sodium Oxybate for Narcolepsy

Extended-release sodium oxybate (Lumryz) is taken once at bedtime for the treatment of cataplexy or excessive daytime sleepiness in adults with narcolepsy. Medscape Medical News source https://www.medscape.com/viewarticle/991464?src=rss

Overcrowding in Quebec's ERs Burdens Patients, Physicians

Recent data show that capacity has exceeded 200% in some hospitals. Medscape Medical News source https://www.medscape.com/viewarticle/991459?src=rss

US Incidence, Prevalence of Myasthenia Gravis Rising

The incidence and prevalence of myasthenia gravis have increased in the United States, likely due to increased diagnosis and more awareness of the disease over time. Medscape Medical News source https://www.medscape.com/viewarticle/991453?src=rss

Erectile Dysfunction Prevalence Spikes in Hyperthyroid Men

Men with hyperthyroidism had a significantly higher prevalence of erectile dysfunction compared with similar men without hyperthyroidism in a meta-analysis of four studies. First Look source https://www.medscape.com/viewarticle/991454?src=rss

Mixed Results on Two Treatments for Erectile Dysfunction

New studies presented at the American Urological Association's 2023 annual meeting offer mixed results for two treatments for erectile dysfunction. Medscape Medical News source https://www.medscape.com/viewarticle/991447?src=rss

Four Profiles Help Identify Kids at Risk for Suicide

The profiles were developed from a study of children and adolescents aged 5–18 years who had been admitted with a neuropsychiatric event to two children's hospital. MDedge News source https://www.medscape.com/viewarticle/991416?src=rss

Contact Allergens Lurk in Diabetes Devices

Once thought to be rare, reports of skin complications related to diabetes devices have been increasing in recent years. Medscape Medical News source https://www.medscape.com/viewarticle/991411?src=rss

Exposure to Air Pollution Linked With Symptomatic Arrhythmia

A study of almost 200,000 people in China found that airborne pollutants are associated with significantly increased risk for cardiac arrhythmias, including atrial fibrillation. Medscape Medical News source https://www.medscape.com/viewarticle/991409?src=rss

Panel Backs Limited New Olaparib Use in Prostate Cancer

An expert panel recommended restricting the expanded first-line indication to patients whose metastatic castration-resistant prostate tumors have BRCA mutations. Medscape Medical News source https://www.medscape.com/viewarticle/991408?src=rss

Have pharmaceutical conflicts of interest unduly influenced asthma guidelines?

The single maintenance and reliever therapy (SMART) treatment approach to patients with asthma, outlined in the article on chronic asthma treatment in the April issue of American Family Physician , has consistent supporting evidence from multiple randomized controlled trials. A practical guide to implementing SMART has been widely disseminated to clinicians. However, an editorial by Dr. Steve Brown cautioned that SMART, which is strongly recommended in the 2022 GINA guidelines , has been “heavily influenced by the pharmaceutical industry,” namely AstraZeneca, which markets budesonide/fomoterol (Symbicort), the combination inhaler primarily studied in the trials: The GINA board of directors and scientific committee members have substantial financial conflicts of interest . Twelve of 17 members, including both chairs, have received personal fees from AstraZeneca. … A 2018 systematic review of SMART for persistent asthma found 16 RCTs, and 15 of those evaluated SMART as a combinatio

Prostate Biopsies a Laughing (Gas) Matter?

Self-administered nitrous oxide was linked to less worry among patients undergoing transrectal procedures, a study found. The same technique is coming for the transperineal approach. Medscape Medical News source https://www.medscape.com/viewarticle/991274?src=rss