Posts

Showing posts from October, 2022

Italian Researchers Study Drug Resistance in Psychiatry

The researchers' goal is to identify molecular markers and clinical data that identify patients who are likely to respond to treatment and those who are likely to be nonresponders. Medscape Medical News source https://www.medscape.com/viewarticle/983271?src=rss

A Cost-Effective De-escalation Strategy in Advanced Melanoma

Response-adapted de-escalation of ipilimumab in patients with advanced melanoma has the potential to lower healthcare costs. Medscape Medical News source https://www.medscape.com/viewarticle/983269?src=rss

Can MS Be Stopped Early in its Tracks?

The first randomized trial of a disease-modifying therapy in radiological isolated syndrome, the earliest pre-clinical phase of MS, suggests dimethyl fumarate reduced the risk of a first clinical event by 80%. Medscape Medical News source https://www.medscape.com/viewarticle/983262?src=rss

Nicotine Blocks Estrogen Production in Women’s Brains

A single dose of nicotine equivalent to one cigarette appears to block estrogen production in an area of the brain linked to addiction, suggests a small, innovative study conducted in healthy women. Medscape Medical News source https://www.medscape.com/viewarticle/983263?src=rss

Ethiopia's Tigray Runs Out of Medical Supplies Amid Health Crisis: WHO

Ethiopia's Tigray region has run out of medical supplies such as vaccines, antibiotics, and insulin, World Health Organization officials said on Friday. Reuters Health Information source https://www.medscape.com/viewarticle/983177?src=rss

Oral FMT on Par With Colonic FMT for Recurrent C difficile

Freeze-dried, encapsulated fecal microbiota transplantation (FMT) has a safety and effectiveness profile similar to that of liquid colonic FMT, without the procedural risks of colonoscopy. Medscape Medical News source https://www.medscape.com/viewarticle/983251?src=rss

Off-Hour Calls; Disabled Patients; and Birdsong for Anxiety

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/983147?src=rss

Imperfect prevention strategies against malaria and cancer

Two recent articles in American Family Physician  highlight new prevention and detection strategies against age-old health threats. In " Malaria: Prevention, Diagnosis, and Treatment ," Drs. S. David Shahbodaghi and Nicholas Rathjen review not only prescribing prophylaxis for travelers to malaria-endemic regions, but also "the first malaria vaccine approved for widespread use ... for the prevention of P. falciparum malaria in children living in endemic areas," which has already been given "to more than 1 million children in Ghana, Malawi, and Kenya." In a previous blog post , Dr. Jennifer Middleton discussed the World Health Organization's endorsement of Mosquirix and research evidence that it lowers the incidence of malaria infection, complications and death in combination with seasonal chemoprophylaxis. A New York Times article  elaborated on the financial, logistical, and trust challenges of getting an estimated 100 million vaccine doses into chi

Combining Treatments for Scar Revision Often a Useful Approach

Outcomes may improve by combining different treatment options, but the type of scar drives the type of modality to consider, according to Dr Arisa Ortiz of UC San Diego. MDedge News source https://www.medscape.com/viewarticle/983182?src=rss

Intensive BP Lowering Harmful in Acute Ischemic Stroke

The ENCHANTED2/MT trial, which was investigating intensive lowering of blood pressure in acute ischemic stroke patients after mechanical thrombectomy, has been stopped early due to safety concerns. Medscape Medical News source https://www.medscape.com/viewarticle/983176?src=rss

Secondary RAS Mutations Linked to Thyroid Cancer Severity, Mortality

The 'double' mutations correlate with 10-times higher mortality in differentiated thyroid cancer, but some question the prognostic value of molecular diagnostics. Medscape Medical News source https://www.medscape.com/viewarticle/983175?src=rss

NIH to Test Pfizer's Paxlovid for Long COVID

The National Institutes of Health's $1 billion RECOVER Initiative has picked Pfizer Inc's antiviral drug Paxlovid as the first treatment it will study in patients with long COVID, organizers of the study said on Thursday. Reuters Health Information source https://www.medscape.com/viewarticle/983150?src=rss

Gilead Profit Tops Expectations Despite Lower COVID Drug Sales, Outlook Raised

Gilead Sciences on Thursday posted a higher-than-expected third-quarter profit on the back of strong demand for its HIV and cancer drugs, which helped offset lower sales of its COVID-19 antiviral drug and acquisition expenses. Reuters Health Information source https://www.medscape.com/viewarticle/983145?src=rss

Is pCR a Reliable Survival Surrogate in Breast Cancer Trials?

Pathologic complete response (pCR) is not a reliable surrogate endpoint in neoadjuvant therapy trials for early breast cancer; alternatives are needed, researchers said. Medscape Medical News source https://www.medscape.com/viewarticle/983165?src=rss

Cancer Deaths Fall; Women's Weight Loss; and Palliative Sedation

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/983080?src=rss

Healthcare Workers Face Unimaginable Decisions in Ukraine

More than 900 medical facilities have been destroyed or damaged, says Ruslan Zelinskyi, MS, from the Spizhenko Clinic in Ukraine. MDedge News source https://www.medscape.com/viewarticle/983121?src=rss

'Eye-opening': Asking About Sexual Function After Brachytherapy

Women who undergo brachytherapy for cervical cancer are hardly ever asked about their sexual function, while men who undergo treatment for prostate cancer are almost always assessed, US researchers have found. Medscape Medical News source https://www.medscape.com/viewarticle/983114?src=rss

What Is Palliative Sedation, and How Is It Administered?

Unlike medically assisted death, palliative sedation aims to reduce the perception of an otherwise intolerable symptom. Systematic education about palliative sedation has been lacking. Medscape Medical News source https://www.medscape.com/viewarticle/983097?src=rss

No Need for Intensive Follow-up of Endometrial Cancer

A pragmatic study shows that patients with endometrial cancer who have intensive follow-up do not have better overall survival that patients who have minimal follow-up. Medscape Medical News source https://www.medscape.com/viewarticle/983092?src=rss

Fungal Pathogens; 'Tripledemic' Possible; and Why We Like Horror

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/983011?src=rss

Finerenone Signals Pneumonia, COVID-19 Benefits

Secondary analyses from 13,026 people with type 2 diabetes and CKD in the finerenone pivotal trials showed that the agent was linked with less infective pneumonia and blunted COVID-19 severity. Medscape Medical News source https://www.medscape.com/viewarticle/983036?src=rss

Low-Carbohydrate Diet Reduces A1c in Diabetes, Prediabetes

A 6-month study showed significant A1c reductions in people with untreated baseline levels of 6.0% to 6.9%, but the mechanism may have been weight loss rather than diet. Medscape Medical News source https://www.medscape.com/viewarticle/983033?src=rss

Black Canadians Face Barriers to Equitable Cancer Care

Better data collection, health literacy, and cultural awareness can help reduce barriers to access and promote equality in care. Medscape Medical News source https://www.medscape.com/viewarticle/983041?src=rss

Drug Shortages Are on the Rise in France

The number of pharmacy supply disruptions lasting at least a week has almost doubled since the start of the year. One pharmacist fears that the situation will worsen. Medscape Medical News source https://www.medscape.com/viewarticle/983028?src=rss

Highly Selective Bailout GPI May Benefit in STEMI-PCI Subgroup

Bailout GP IIb/IIIa inhibition ups bleeding risk without preventing ischemic events in STEMI-PCI patients also having thrombectomy, a registry study suggests. One subgroup may have had a net benefit. First Look source https://www.medscape.com/viewarticle/983025?src=rss

Liquid Biopsy for Solid Tumors Also IDs Risk for Blood Cancer

A liquid biopsy test used for molecular profiling in patients with solid tumors also identified patients who were at risk for clonal hematopoiesis, which may develop into myeloid blood cancer. Medscape Medical News source https://www.medscape.com/viewarticle/983023?src=rss

Misusing Science; Breaking Bad News; and Doctors Who Kill

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982939?src=rss

Violence Takes Toll on Canadian Healthcare Workers

For many physicians and other healthcare workers, being abused on the job has become almost routine. Medscape Medical News source https://www.medscape.com/viewarticle/982962?src=rss

Possible Salvage Option for Refractory/Recurrent CNS Lymphoma

An effective salvage regimen is lacking for these patients. This study shows cytarabine plus temozolomide may be an option. The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/982963?src=rss

Gloom Lifting as MCL Treatments Evolve

'Prognosis has certainly changed in past 10 years. We have been able to have an excellent control of disease, and patients are living longer,' says the co-author of a recent review. MDedge News source https://www.medscape.com/viewarticle/982961?src=rss

Explaining RT Boosts Patient Satisfaction, Reduces Anxiety

Getting medical physicists involved with patient care by having them explain what will be involved helps to reduce patient anxiety and increases overall patient satisfaction, suggest results of a new trial. Medscape Medical News source https://www.medscape.com/viewarticle/982959?src=rss

Coping With a Cancer Patient's Anger

Are you the target of your oncology patients' emotions? Medscape Reader Polls source https://www.medscape.com/viewarticle/982958?src=rss

In Epilepsy, Heart Issues Linked to Longer Disease Duration

A new study finds that abnormalities in electrocardiograms are linked to an earlier age of diagnosis and longer epilepsy duration. MDedge News source https://www.medscape.com/viewarticle/982956?src=rss

Bone Metastases Treated in a FLASH: One Dose of Proton RT

The first-in-human trial of FLASH ultra-high-dose-rate proton radiotherapy shows that it offers pain relief with few toxicities to cancer patients with bone metastases. Medscape Medical News source https://www.medscape.com/viewarticle/982952?src=rss

Psychosis and Dementia; Apps for Stroke Care; and Strange Diseases

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982863?src=rss

Patients With Schizophrenia Twice as Likely to Develop Dementia?

Patients with psychotic orders are at substantially higher risk of developing dementia, especially those diagnosed with psychosis at an earlier age, new research suggests. Medscape Medical News source https://www.medscape.com/viewarticle/982913?src=rss

FDA Approves New Immunotherapy Combo for Liver Cancer

The new combination includes a priming dose of the CTLA-4 antibody tremelimumab, which is approved for the first time worldwide. FDA Approvals source https://www.medscape.com/viewarticle/982911?src=rss

How Early Can Imaging Assess Response in End-Stage Prostate Cancer?

177Lu-PSMA SPECT at cycle three (week 12) of six cycles of PSMA-targeted treatment predicted progression-free survival for men with end-stage metastatic castration-resistant prostate cancer. Medscape Medical News source https://www.medscape.com/viewarticle/982909?src=rss

Stroke Management: There’s an App for That

Apps can improve the management of acute and chronic stages of stroke, facilitate rapid treatment, and enhance communication between emergency medical services and hospital staff. Medscape Medical News source https://www.medscape.com/viewarticle/982914?src=rss

IBD Drugs 'Prohibitively' Expensive for Medicare Patients

Over their lifetime, Medicare patients with IBD can expect to shell out tens to hundreds of thousands of dollars in out-of-pocket costs for needed medications. Medscape Medical News source https://www.medscape.com/viewarticle/982908?src=rss

Stopping Levothyroxine in Subclinical Hypothyroidism Safe, Feasible

Despite apparent lack of benefits, many still receive levothyroxine for subclinical hypothyroidism. Study helps fill a data gap on discontinuation. Medscape Medical News source https://www.medscape.com/viewarticle/982905?src=rss

FDA Approves Upadacitinib (Rinvoq) for Sixth Indication

Upadacitinib's approval for nonradiographic axial spondyloarthritis marks the sixth indication in the US for the Janus kinase inhibitor. FDA Approvals source https://www.medscape.com/viewarticle/982902?src=rss

COVID Lawsuits; Sex and Disabled Youth; and Help for Trans Women

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982799?src=rss

Circulating Tumor DNA Test May Help Guide GI Cancer Management

A ctDNA test may be sensitive enough to assess tumor burden and help guide treatment plans for people with locally advanced or metastatic colorectal cancer. Medscape Medical News source https://www.medscape.com/viewarticle/982900?src=rss

Maternal Deaths Show 'Racism Does Exist Among Physicians'

Black women had a higher chance of dying at a hospital during childbirth, even when income and other social determinants of health were excluded, a new study found. Medscape Medical News source https://www.medscape.com/viewarticle/982865?src=rss

CDC Advisers Approve Adding COVID Shots to Vaccine Schedules

The CDC advisory committee on vaccines on Thursday approved adding COVID-19 vaccines to the agency's recommended immunization schedules for both children and adults. Reuters Health Information source https://www.medscape.com/viewarticle/982788?src=rss

Sexual Healthcare for Disabled Youth: Tough and Getting Tougher

Talking to disabled adolescents and young adults about reproductive health can be a challenge even for the most experienced clinicians. Medscape Medical News source https://www.medscape.com/viewarticle/982825?src=rss

The Periodontitis-Diabetes Link Goes Both Ways

Incident periodontitis was significantly higher among people with type 2 diabetes, and those with periodontitis had an elevated rate of incident diabetes, in a retrospective study of Taiwanese adults. First Look source https://www.medscape.com/viewarticle/982822?src=rss

New Consensus on Managing Nausea and Vomiting in Pregnancy

A working group from the National College of French Gynecologists and Obstetricians has established a consensus on the definition and management of these symptoms. Medscape Medical News source https://www.medscape.com/viewarticle/982826?src=rss

Autochthonous Transmission of Dengue Fever Rising in France

Climate change, the territorial expansion of the mosquito vector, and the increase in global travel have facilitated the transmission of dengue fever in France. Medscape Medical News source https://www.medscape.com/viewarticle/982823?src=rss

Suicidal Ideation Associated With Increased Alcohol Use During Pandemic

Participants in the Survey on COVID-19 Mental Health who reported heavy drinking during the past month also faced higher risks for suicidal ideation. Medscape Medical News source https://www.medscape.com/viewarticle/982820?src=rss

COVID Lawsuits Have Arrived: Which Doctors Are at Risk?

COVID-related lawsuits against physicians in many specialties are starting to roll in. What's likely to be the outcome? Medscape Medical News source https://www.medscape.com/viewarticle/982810?src=rss

1 in 7 Mortality Postsurgery; ECT and MDE; and Monkeypox News

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982744?src=rss

Physicians Talking: Time and Family Demands Make Friendships Difficult

Medscape surveyed physicians about how successfully they are creating networks of supportive friends amid the demands of work and family. Here’s what your colleagues are saying. Medscape Medical News source https://www.medscape.com/viewarticle/982772?src=rss

One in Seven Older Adults Die Within a Year After Surgery

Experts called the finding of especially high mortality of individuals with frail health or dementia a sign of 'a break in the system.' Medscape Medical News source https://www.medscape.com/viewarticle/982763?src=rss

Antiviral Therapy Improves Survival After Liver Cancer Surgery

The analysis focused on elderly patients after hepatectomy for hepatitis B virus–related hepatocellular carcinoma. The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/982766?src=rss

About 1 in 8 Oral Cancer Drug Prescriptions Never Reach the Patient. Why?

Although most patients do receive their oral cancer drugs, researchers wanted to understand why some patients don't. Medscape Medical News source https://www.medscape.com/viewarticle/982764?src=rss

Surgeons Begin Accepting Industry Payments Soon After Graduation

Lucrative financial relationships between physicians and industry are ubiquitous, but a new study uncovers just how early these partnerships — and potential conflicts of interest — can arise. Medscape Medical News source https://www.medscape.com/viewarticle/982761?src=rss

Jury Decides Against Hospital, Surgeon Who Committed Suicide; More

Botched ankle surgery was alleged in suit; docs used permanent instead of temporary stitches; what's causing big personal injury payouts? Medscape Business of Medicine source https://www.medscape.com/viewarticle/982759?src=rss

Energy-Based Treatment Combination Improves Becker's Nevi

The study is the largest known case series of therapy combining 1550-nm nonablative fractional resurfacing and laser hair removal for Becker's nevus patients with skin types III-VI. MDedge News source https://www.medscape.com/viewarticle/982756?src=rss

Healthy Diet, Less News Key to Preventing Anxiety During COVID

Eating well and avoiding stressful news helped prevent anxiety and depressive symptoms during the COVID-19 pandemic -- although social contact showed no benefit, new research suggests. Medscape Medical News source https://www.medscape.com/viewarticle/982711?src=rss

Audit Hits N. Dakota on Vaccine Handling; Agency Disputes It

“DoH uses redundant systems to ensure proper monitoring and distribution of vaccines prior to end of shelf life,” the agency said. Associated Press source https://www.medscape.com/viewarticle/982697?src=rss

White House Urges People Over 50 to Get Boosters Right Away

“If you’re over 50, certainly if you’re over 65, you’ve got to go get these vaccines because it actually, literally could save your life.” WebMD Health News source https://www.medscape.com/viewarticle/982688?src=rss

Indonesia Reports 99 Child Deaths From Acute Kidney Injury This Year

Close to 100 children in Indonesia have died from acute kidney injury (AKI) so far this year, a health ministry official said on Wednesday, as a team of experts investigates the spike in cases. Reuters Health Information source https://www.medscape.com/viewarticle/982670?src=rss

US Nears Record Poultry Deaths From Bird Flu

A near-record number of US chickens and turkeys have died in this year's outbreak of avian flu, as a different form of the virus than farmers battled before has infected more wild birds that then transmit the disease, officials said. Reuters Health Information source https://www.medscape.com/viewarticle/982600?src=rss

What Makes a Healthy Gut Microbiome?

Home tests promise big but deliver small, a new study found. Medscape Medical News source https://www.medscape.com/viewarticle/982679?src=rss

COVID Isolation Too Short; Diet and Dementia; and Long COVID Drug

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982592?src=rss

Trump Administration Blocked CDC Transit Mask Mandate, Report Shows

Former President Donald Trump's administration at a crucial time in the COVID-19 pandemic in 2020 blocked the CDC from adopting a federal mandate requiring face masks on airline flights and other forms of transit, a congressional report released on Monday said. Reuters Health Information source https://www.medscape.com/viewarticle/982574?src=rss

Most Pediatric Myocarditis Caused by Viruses

A pediatric cardiologist from UT Southwestern in Dallas, presenting at the American Academy of Pediatrics Conference, recommended improved diagnostics and treatment for myocarditis. MDedge News source https://www.medscape.com/viewarticle/982609?src=rss

Planned Parenthood Asks North Carolina Court to Let More Health Workers Provide Abortions

North Carolina abortion providers on Monday asked a state court to allow health professionals other than physicians to provide medication abortions, as clinics struggle to accommodate an influx of abortion patients from across the U.S. South. Reuters Health Information source https://www.medscape.com/viewarticle/982547?src=rss

Breast Cancer Rates Falling in Childhood Cancer Survivors

Invasive breast cancer rates among female childhood cancer survivors have modestly fallen over time, especially among survivors younger than 40. Medscape Medical News source https://www.medscape.com/viewarticle/982607?src=rss

Vonoprazan Promising for Erosive Esophagitis

The oral potassium-competitive acid blocker vonoprazan was noninferior and superior to the proton pump inhibitor lansoprazole for erosive esophagitis in a phase 3 trial. Medscape Medical News source https://www.medscape.com/viewarticle/982598?src=rss

Doctors Behave Badly; US Stillbirths Stay High; and Gun Safety

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982502?src=rss

Gambia Says Child Deaths Linked to Cough Syrup Have Risen to 70

Gambia's government on Friday said the number of child deaths from acute kidney injury, thought to be linked to Indian-made cough syrups, has risen to 70 from a previous toll of 69. Reuters Health Information source https://www.medscape.com/viewarticle/982501?src=rss

Sepsis Predictor Tool Falls Short in Emergency Setting

Patterns of time to antibiotic use were inconsistent; some patients with severe sepsis did not receive antibiotics within 6 hours of triage. Medscape Medical News source https://www.medscape.com/viewarticle/982534?src=rss

Sepsis Transition Program May Lower Mortality in Certain Patients

A navigator-led sepsis transition and recovery program may reduce 30-day mortality and readmission among sepsis survivors sent to post-acute care. Medscape Medical News source https://www.medscape.com/viewarticle/982527?src=rss

Canadian Doctors Call for Mental Health Funding

Although rates of new mental health diagnoses are rising, Canadians often have trouble finding care. Medscape Medical News source https://www.medscape.com/viewarticle/982537?src=rss

Bill & Melinda Gates Foundation Pledge $1.2 Billion to Eradicate Polio

Bill & Melinda Gates Foundation said on Sunday that it will commit $1.2 billion to support efforts to end all forms of polio globally. Reuters Health Information source https://www.medscape.com/viewarticle/982512?src=rss

Physicians Talking: Why Doctors May Act Poorly

Medscape asked over 1500 physicians if they had witnessed misbehavior in their colleagues, and why it may have occurred. Stress emerged as a key driver, along with changing social mores and personality traits. Medscape Medical News source https://www.medscape.com/viewarticle/982526?src=rss

Physicians Rebel at Discussing Gun Safety With Patients

An analysis of several years of comments on Medscape blogs shows a significantly negative reaction to including gun safety in doctors' talks with patients. Medscape Medical News source https://www.medscape.com/viewarticle/982463?src=rss

Patient Skepticism; Psych Follow-up Lags; and Weed Weight Loss

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982442?src=rss

Targeted Radionuclide Boosts Survival in Pancreatic Tumors

A phase 2 trial of lutetium-octreotate in patients with unresectable progressive pancreatic neuroendocrine tumors shows nearly double the 1-year survival rate compared with sunitinib at standard dose. Medscape Medical News source https://www.medscape.com/viewarticle/982514?src=rss

High PSMA Predicts Targeted Therapy Response in Prostate Cancer

High PSMA (mean SUV of 10 or greater) predicts good response to 177Lu-PSMA-617 and promises to help clinicians optimize the best patients to treat with the radioligand therapy, researchers say. Medscape Medical News source https://www.medscape.com/viewarticle/982513?src=rss

Can Amazon cure all that ails U.S. primary care?

This summer, Amazon purchased the One Medical  national chain of primary care practices for nearly $4 billion. As David Blumenthal and Lovisa Gustafsson recently wrote in the Harvard Business Review , the success of the online retail giant's health care venture is hardly assured. One doesn't need to be a practicing family physician with health policy expertise to know that U.S. primary care is chronically overworked and underfunded, and as a result, medical student interest in primary care specialties  has been anemic for the past two decades . As I discussed in a previous Medscape commentary , international primary care comparisons are less than flattering. The "fundamental question," asserted Blumenthal and Gustafsson, is: "Can profit-driven entrepreneurship and bottom-up innovation make the U.S. health care system work anywhere nearly as well as those in places like France, Sweden, Norway, Australia, the Netherlands, New Zealand, Germany, and Switzerland?"

Gabapentin increases postoperative risks in older adults

Although gabapentin is effective at relieving some types of neuropathic pain, namely diabetic neuropathy and postherpetic neuralgia , it is notably ineffective for treating other types, such as radicular low back pain . A 2019 editorial in American Family Physician  warned of potential unintended consequences of using gabapentinoids (gabapentin and pregabalin) as alternatives to opioids for pain management. The authors observed that "as many as one in three patients taking therapeutic doses will experience dizziness or somnolence"; also, the U.S. Food and Drug Administration issued a safety communication  about gabapentinoids causing serious breathing problems in patients with chronic respiratory diseases and older patients. Illicit use of gabapentin is playing an increased role in opioid-related overdoses, according to a May 2022 report from the Centers for Disease Control and Prevention. The report found that between 2019 and 2020, toxicology results detected gabapentin

Weight Loss Gadgets Provide Data to Help Users Reach Diet Goals

You may have seen the ads that promise weight loss by giving you data on how your body reacts to food, exercise, and sleep. Is this information enough to help consumers achieve their goals? Kaiser Health News source https://www.medscape.com/viewarticle/982476?src=rss

New Trials in Gynecologic Cancers: Could Your Patient Benefit?

Perhaps one of your patients could benefit from clinical trials of novel drugs that are currently recruiting patients with gynecologic cancers. Medscape Medical News source https://www.medscape.com/viewarticle/982475?src=rss

New FDA Guidance Aims to Boost Access to Opioid-Reversal Drug

Under new guidance, harm reduction programs distributing naloxone will be exempt from certain federal requirements in an effort to increase access to the opioid antidote. Medscape Medical News source https://www.medscape.com/viewarticle/982472?src=rss

AF Detection by Smartwatch Challenging in Some Patients

Coexisting ECG anomalies may affect the accuracy of the watch’s detection algorithms. Medscape Medical News source https://www.medscape.com/viewarticle/982473?src=rss

New Deep Dive Into Paxlovid Interactions With CVD Meds

A new review paper tackles potential drug-drug interactions with the antiviral drug and today's most commonly prescribed cardiovascular drugs. Medscape Medical News source https://www.medscape.com/viewarticle/982469?src=rss

One Third of Pancreatic Cancer Diagnoses Missed on Scans

An analysis of post-imaging pancreatic cancer diagnoses suggests that in 36% of cases, there were signs on CT and MRI scans that had been missed. Medscape Medical News source https://www.medscape.com/viewarticle/982460?src=rss

Are Doctor Privacy Agreements Ethical?; Long COVID-19 More Prevalent Than Thought; and Creating a Safe LGBTQ+ Health Space

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982366?src=rss

Success for Basilar Artery Stroke Thrombectomy: Trials Published

Two randomized trials have shown benefits of endovascular therapy for Chinese patients with moderate to severe basilar artery ischemic strokes, but further trials are warranted in broader populations. Medscape Medical News source https://www.medscape.com/viewarticle/982391?src=rss

Cardiac Biomarkers Track With Hormone Therapy in Transgender People

A pilot study spotlights concentration differences in two common biomarkers of cardiac disease as well as the need for greater inclusivity in cardiovascular trials. Medscape Medical News source https://www.medscape.com/viewarticle/982380?src=rss

Get COVID Boosters by Halloween, White House Advises

"We could save hundreds of lives each day this winter" if more people would get the shots, said Ashish Jha, MD, the White House COVID-19 coordinator. WebMD Health News source https://www.medscape.com/viewarticle/982381?src=rss

Psychiatrist Sentenced to 11 Years for Sledgehammer Attack

Pamela Buchbinder, a New York psychiatrist whose licence has been suspended pending an investigation, was sentenced to 11 years in state prison for her role in attempting to murder her child's father. Medscape Medical News source https://www.medscape.com/viewarticle/982376?src=rss

Radiation-Induced Meningiomas Worse Than Spontaneous Lesions

Radiation-induced meningiomas were more likely to recur and were more aggressive. The study was published as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/982375?src=rss

Intensive Blood Pressure Reduction Benefits Malignant LVH

Intensive blood pressure lowering has substantial benefits for both the prevention and treatment of malignant left ventricular hypertrophy, a new analysis of the SPRINT trial shows. Medscape Medical News source https://www.medscape.com/viewarticle/982374?src=rss

Best Practices for an LGBTQ+ Friendly Medical Space

Though a growing percentage of the population identifies as LGBTQ+, some community members still feel unseen when they visit a medical space. Here are some best practice ideas for LGBTQ+ friendly care. Medscape Medical News source https://www.medscape.com/viewarticle/982373?src=rss

How Far Is Too Far to Protect Your Reputation Online?

Patient-doctor privacy agreements may be appealing, but they exist in a hazy ethical and legal zone and may backfire, experts say. Medscape Medical News source https://www.medscape.com/viewarticle/982319?src=rss

Cancer Care in Women; Vision, Depression Link; Neighbors Do Well With Same Doc

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982285?src=rss

Vaccination Tied to Lower Mortality in Ventilated COVID Patients

Data suggest that the benefits of vaccination go beyond preventing mechanical ventilation. Medscape Medical News source https://www.medscape.com/viewarticle/982309?src=rss

Children and COVID: Downward Trend Reverses With Small Increases

The 40,656 new cases reported bring the US cumulative count of child COVID-19 cases to over 14.8 million since the pandemic began. MDedge News source https://www.medscape.com/viewarticle/982308?src=rss

Neighbors Who Share a Doctor Have Better Health Outcomes

Patients of the same family physician practice who live close to each other have better cardiovascular and health outcomes than those who live farther apart, a retrospective study suggests. Medscape Medical News source https://www.medscape.com/viewarticle/982306?src=rss

Urticaria During Pregnancy: Study Analyzes Outcomes, Treatments

The study involved 288 pregnancies in women with chronic urticaria who were part of an international, multicenter study of the Urticaria Centers of Reference and Excellence (UCARE) network. MDedge News source https://www.medscape.com/viewarticle/982304?src=rss

Pregnant Women With Disabilities at Higher Risk for Violence

Pregnant or postpartum women with disabilities are at relatively high risk of experiencing violence, often from the people closest to them, new research suggests. MDedge News source https://www.medscape.com/viewarticle/982301?src=rss

Do You Take Your Own Advice on Healthy Habits?

How well do you follow your own "healthy habits" advice? Medscape Reader Polls source https://www.medscape.com/viewarticle/982297?src=rss

COVID Lying; History of Dopamine; and Older Patients Mixing Meds

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982194?src=rss

Sleep Study Aids Diagnosis of Functional Neurologic Disorder

A video-monitored sleep study helped clinicians diagnose a functional neurologic disorder and promoted the patient's recovery. Medscape Medical News source https://www.medscape.com/viewarticle/982245?src=rss

Unique Transcriptional Coronary Endothelial Cell Pattern in COVID

Digital spatial transcriptomic profiling of coronary endothelial cells shows differential expression patterns for SARS-CoV-2 myocarditis. First Look source https://www.medscape.com/viewarticle/982240?src=rss

Reduced Exercise Capacity Further Explained in Untreated OSA

Patients with obstructive sleep apnea have evidence of pulmonary gas exchange abnormalities and resting vascular dysfunction. Medscape Medical News source https://www.medscape.com/viewarticle/982235?src=rss

Weight Loss History Affects Success in Obesity Management

A retrospective study of patients at a Canadian weight-loss clinic yields a surprising finding about the success of older women with experience in dieting. Medscape Medical News source https://www.medscape.com/viewarticle/982244?src=rss

Melanoma Increases: a UV Exposure or Diagnostic Scrutiny Problem?

A new analysis found that proxies of high medical scrutiny correlate with higher melanoma incidence, while proxies of UV radiation exposure show weak or no correlations. Medscape Medical News source https://www.medscape.com/viewarticle/982238?src=rss

Adding Cardiac Shockwave to CABG Boosts LVEF, Function, QoL

Direct epicardial cardiac shockwave therapy adjunctive to CABG might lead to a paradigm shift in the treatment of ischemic cardiomyopathy, researchers suggest. Medscape Medical News source https://www.medscape.com/viewarticle/982233?src=rss

Dual Therapy Restores Radioiodine Uptake in Thyroid Cancer

Investigators addressed the "holy grail" in thyroid oncology: how to jump-start radioactive iodine when it stops working for patients with thyroid cancer. Medscape Medical News source https://www.medscape.com/viewarticle/982205?src=rss

COVID Outlook; Docs Refuse Opioid Disorder; Cancer Vax Hope?

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/982100?src=rss

Video Games Trigger Dangerous Arrhythmias in Some Children

Although such events are rare in children and adolescents, they are on the rise and can be lethal, experts caution. Medscape Medical News source https://www.medscape.com/viewarticle/982197?src=rss

Hair Cortisol Is a Biomarker of Chronic Stress

Researchers found a significant correlation between perceived stress in the past month and hair cortisol concentration in a 3-centimeter fragment. Medscape Medical News source https://www.medscape.com/viewarticle/982146?src=rss

86% of Kids Have COVID Antibodies From Infection

As of August, 86% of children aged 6 months to 17 years have had at least one SARS-CoV-2 infection, which is up from 75% in April. WebMD Health News source https://www.medscape.com/viewarticle/982145?src=rss

Colonoscopy Lowers CRC Risk and Death, but Not by Much: NordICC

In an intention-to-screen analysis, 10-year results from the NordICC trial show that colonoscopy reduces the risk of colorectal cancer by only 18%. Medscape Medical News source https://www.medscape.com/viewarticle/982143?src=rss

Physicians Speak Out: Why They Love or Hate Incentive Bonuses

Incentive bonuses have been a part of many physicians' salaries for decades. Medscape polled over 400 physicians and asked what they think about their bonus and the metrics they must meet to earn it. Medscape Medical News source https://www.medscape.com/viewarticle/982137?src=rss

New ICD-10-CM Codes a 'Big Switch-Over'

The coding changes for major and mild neurocognitive disorders represent the most consequential coding changes for DSM-5 disorders since 2015. Medscape Medical News source https://www.medscape.com/viewarticle/982128?src=rss

ED Violence Rises; Get Paid Faster; and Weightlifting's Benefits

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/981995?src=rss

Type 1 Diabetes Complications Tied to Gut Microbiome Changes

Alterations to composition and function of the gut microbiome have been identified in people with type 1 diabetes complications, with the greatest changes found in those with diabetic nephropathy. Medscape Medical News source https://www.medscape.com/viewarticle/982120?src=rss

Pediatricians Urged to Check for Vision Problems After Concussion

The American Academy of Pediatrics is raising awareness on how concussion-related vision deficits can interfere with schoolwork and other activities. Medscape Medical News source https://www.medscape.com/viewarticle/982098?src=rss

Northern Indiana Residents Warned About Mosquito-Borne Virus

While rare, the virus can cause serious illness and has a fatality rate of around 33% or higher. Associated Press source https://www.medscape.com/viewarticle/982118?src=rss

Youth Killed by Guns in US Equals Classroom a Day

The American Academy of Pediatrics released an updated policy statement and technical report about 'the No. 1 killer of youth through age 24' in the United States. Medscape Medical News source https://www.medscape.com/viewarticle/982117?src=rss

Most People With Long COVID-19 Report Trouble With Daily Tasks

For 15% of adults with COVID-19, symptoms linger for weeks or months after they begin to recover. WebMD Health News source https://www.medscape.com/viewarticle/982048?src=rss

Pumping Iron Improves Longevity in Older Adults

Those who report weightlifting show reductions in all-cause and cardiovascular disease-related mortality. Medscape Medical News source https://www.medscape.com/viewarticle/982033?src=rss

Nearly a Third of Pheochromocytoma Patients Are Normotensive

A review of 524 patients who underwent removal of a pheochromocytoma at a single center in China identified characteristics that distinguished those with hypertension from those with normotension. First Look source https://www.medscape.com/viewarticle/982034?src=rss

Should Doctors Buy an Electric Car?

There are many benefits to driving electric cars but the infrastructure still needs improvement. What are the pros and cons and what may change? Medscape Medical News source https://www.medscape.com/viewarticle/982032?src=rss

US Pharmacies to Offer Hearing Aids by Mid-October Under New Govt Rule

Major US pharmacy operators Walgreens Boots Alliance and Walmart said on Thursday that in mid-October they would start selling hearing aids over-the-counter. Reuters Health Information source https://www.medscape.com/viewarticle/981996?src=rss

COVID Tied to Spike in Deaths in Liver Disease With Diabetes

The increase in liver disease–related mortality among people with diabetes during the pandemic was associated with more deaths due to nonalcoholic fatty liver disease and alcohol-related liver disease. Medscape Medical News source https://www.medscape.com/viewarticle/982020?src=rss

New Insurance to Cover Docs' Post-Roe Legal Battles Over Abortion

As physicians grapple with post-Roe legal liability over abortion, a malpractice insurer launches add-on coverage for criminal prosecutions. Medscape Medical News source https://www.medscape.com/viewarticle/982018?src=rss

Eat Early, Lose Weight; New Sepsis Detection; and Menopause Risks

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/981936?src=rss

Provider-Only Care Benefits Patients in the ED

A protocol created to manage COVID case surges and staff shortages reduced ED time with no additional provider hours. Medscape Medical News source https://www.medscape.com/viewarticle/981958?src=rss

Eating Earlier Offers Health Benefits, Studies Say

"You have this internal biological clock that makes you better at doing different things at different times of the day." WebMD Health News source https://www.medscape.com/viewarticle/981955?src=rss

Children and COVID: Weekly Cases Dropped by 57% in September

The new-case total of 39,200 for the week of Sept. 23-29 was down by almost 28% from the previous week. MDedge News source https://www.medscape.com/viewarticle/981956?src=rss

New Mexico Urges Syphilis Testing for All Pregnant Mothers

The state health department says that New Mexico had the highest rate of congenital syphilis cases among states in 2020. Associated Press source https://www.medscape.com/viewarticle/981953?src=rss

Lifestyle During Menopause Affects Cardiovascular Mortality

Smoking, the consumption of vegetables, sleep, and physical activity are associated with the risk of cardiovascular mortality in menopausal women, according to a recent Spanish study. Medscape Medical News source https://www.medscape.com/viewarticle/981952?src=rss

Worsening HFpEF Linked With Low T3/T4 Ratio

Among patients with heart failure with preserved ejection fraction (HfpEF), a low ratio of free triiodothyronine (T3) to free thyroxine (T4) was significantly associated with worsening HF. First Look source https://www.medscape.com/viewarticle/981946?src=rss

Too Old to Practice? Physicians Who Bully; and Monkeypox Mutates

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/981886?src=rss

When Failure to Correct a Flawed Paper Could Put Lives at Risk

A paper claimed that vasopressin, also known as antidiuretic hormone, worsened SARS-CoV-2 infections. Retraction Watch source https://www.medscape.com/viewarticle/981905?src=rss

Nifedipine During Labor Controls BP in Severe Preeclampsia

For women with preeclampsia with severe features who are undergoing induction of labor, initiation of long-acting oral nifedipine every 24 hours should be considered, researchers say. Medscape Medical News source https://www.medscape.com/viewarticle/981901?src=rss

ICH Patients at Increased Risk of Subsequent Vascular Events

Patients with prior intracerebral hemorrhage have higher rates of major ischemic and hemorrhagic events than the general population, emphasizing the need for better secondary preventive measures. Medscape Medical News source https://www.medscape.com/viewarticle/981899?src=rss

Too Old to Practice Medicine?

In Brazil, there is no age limit for practicing medicine. Many Brazilian physicians support periodic self-evaluations, but not mandatory age-related assessments. Medscape Medical News source https://www.medscape.com/viewarticle/981897?src=rss

Michigan Judge Drops Charges in Flint Water Crisis

A Michigan judge on Tuesday threw out felony charges against seven former state and local officials in connection with the Flint water scandal. Reuters Health Information source https://www.medscape.com/viewarticle/981864?src=rss

Biden to Nominate US Surgeon General to Join WHO Executive Board: Official

President Joe Biden intends to nominate Surgeon General Vivek Murthy to be the US representative on the World Health Organization's executive board, administration officials said on Tuesday. Reuters Health Information source https://www.medscape.com/viewarticle/981856?src=rss

US Abortion Restrictions Mount After Overturn of Roe v Wade

Thirteen states have begun enforcing abortion bans since the US Supreme Court in June overturned Roe v Wade, a swift and dramatic change after nearly 50 years of federal abortion protections. Reuters Health Information source https://www.medscape.com/viewarticle/981848?src=rss

Street Medicine; Folic Acid for Suicidality; and Malaria Vaccines

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/981812?src=rss

In the Aftermath of Medical Errors: Podcast Dives Deep

A new storytelling podcast explored shame among clinicians, in an effort to offer healthcare professionals space to explore their own experiences. Medscape Medical News source https://www.medscape.com/viewarticle/981836?src=rss

Breakthrough Studies Support New Boosters in Immunosuppressed

The findings of two studies underscore the importance of booster vaccine doses in those with immune-mediated inflammatory diseases who are taking immunosuppressants. Medscape Medical News source https://www.medscape.com/viewarticle/981835?src=rss

Will Real Meat Grown in a Lab Be Good for Us?

Produced from a single animal cell, cultivated meat is hailed as a slaughter-free way to feed more people without the environmental harm — and it can be made healthier. But is it too good to be true? WebMD Health News source https://www.medscape.com/viewarticle/981839?src=rss

Comparing Prevention and Neurostimulation for Dementia

Noninvasive neurostimulation is a promising technique that could one day provide treatment for dementia. For now, clinicians continue to stress the importance of preventive measures. Medscape Medical News source https://www.medscape.com/viewarticle/981837?src=rss

Online Tool Predicts Complications From Hysterectomy

Researchers have developed multivariable logistic regression models to provide personalized risk estimates that aid in shared decision-making for patients undergoing hysterectomy for benign disease. Medscape Medical News source https://www.medscape.com/viewarticle/981833?src=rss

Childhood Peanut Allergy Linked With Other Legume Allergies

French children with peanut allergy also tend to have allergies to one or more other legumes, which are likely to cause anaphylactic reactions, researchers in France report. Medscape Medical News source https://www.medscape.com/viewarticle/981827?src=rss

Is Medical Cannabis the Answer to the Opioid Crisis?

A large survey of medical cannabis users with chronic pain and mental health issues shows improvement in health and functioning and reduced opioid use. Medscape Medical News source https://www.medscape.com/viewarticle/981767?src=rss

Distensibility Index: A 'Game Changer' in Pediatric EoE?

Measuring esophageal distensibility can help define the severity of early scarring in the esophagus of children with eosinophilic esophagitis and guide care. Medscape Medical News source https://www.medscape.com/viewarticle/981766?src=rss

Moderna Refused China Request to Reveal Vaccine Technology

Moderna has refused to hand over to China the core intellectual property behind the development of its COVID-19 vaccine, leading to a collapse in negotiations on its sale there, the Financial Times reported on Saturday, citing people familiar with the matter. Reuters Health Information source https://www.medscape.com/viewarticle/981745?src=rss

Amylyx Prices Newly Approved ALS Drug at $158,000 Per Year

Amylyx Pharmaceuticals on Friday set the list price of its newly approved drug to treat amyotrophic lateral sclerosis (ALS) at about $158,000 per year in the United States, a discount to its most recently approved competitor. Reuters Health Information source https://www.medscape.com/viewarticle/981708?src=rss

Gardasil 9 HPV Vaccine Advised for MSM Living With HIV

Italian researchers say the HPV vaccine is needed in young MSM with gonorrhea exposure. The WHO says only 30% of the target population worldwide has received the HPV vaccine. Medscape Medical News source https://www.medscape.com/viewarticle/981757?src=rss

Balanced Fat Intake Links With Less Type 2 Diabetes

Chinese adults whose diet balanced their animal- and vegetable-fat intake had a significantly lower incidence of type 2 diabetes compared with those with a less balanced intake. First Look source https://www.medscape.com/viewarticle/981756?src=rss

Private Practice Pros; Unexplained Immunity; Cancer's Heavy Toll

The top 3 things you should know to start your day. 3 Things to Know Today source https://www.medscape.com/viewarticle/981684?src=rss