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Showing posts from January, 2022

The Superpowers of Butterflies

The color, patterns, and transparency of butterfly wings can serve as self-defense mechanisms, camouflaging them and warding off would-be predators, according to the Marine Biology Laboratory. Quick Take source https://www.medscape.com/viewarticle/967532?src=rss

Experimental Vector-Based COVID-19 Vaccine Could Be Manufactured Like Flu Shots

A COVID-19 vaccine that can be produced locally in low- and middle-income countries is yielding promising results in early clinical trials, researchers say. Reuters Health Information source https://www.medscape.com/viewarticle/967520?src=rss

Preventing Febrile Neutropenia Recurrence in Gynecologic Cancer

New research suggests that high-dose G-CSF can prevent recurrence in women undergoing chemotherapy. The study was published on researchsquare.com as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/967531?src=rss

Pathologists' Assistants Can Alleviate Forensic Burdens

There's a nationwide shortage of medical examiners. Can increased use of pathologists' assistants be the answer? Medscape Medical News source https://www.medscape.com/viewarticle/967530?src=rss

Surrogate Endpoints Acceptable in AML Trials, Says FDA

In the case of drugs used for newly diagnosed acute myeloid leukemia (AML), surrogate endpoints have been validated, says the US Food and Drug Administration. Medscape Medical News source https://www.medscape.com/viewarticle/967529?src=rss

Billionaire Mark Cuban Launches Online Pharmacy for Generics

The owner of the Dallas Mavericks is behind a new online pharmacy looking to lower prices on 100 generic drugs. WebMD Health News source https://www.medscape.com/viewarticle/967525?src=rss

Most Participants Recruited for Walvax mRNA COVID Vaccine Trial

China's Walvax Biotechnology has recruited most of the 28,000 participants needed for a large clinical trial of its mRNA COVID-19 vaccine candidate, a senior company official said on Thursday. Reuters Health Information source https://www.medscape.com/viewarticle/967396?src=rss

Monotherapy or One-Two Punch Against EGFR-Mutant NSCLC?

Standard of care for patients with EGRF+ lung cancer is treatment with an EGRF targeted drug, but should this be monotherapy, or should it be combined with chemotherapy and/or other drugs? Medscape Medical News source https://www.medscape.com/viewarticle/967443?src=rss

COVID Hits One of the Last Uninfected Places on the Planet

When the coronavirus began spreading around the world, the remote Pacific archipelago of Kiribati closed its borders, ensuring the disease didn't reach its shores for nearly two full years. Associated Press source https://www.medscape.com/viewarticle/967454?src=rss

Deaths Due to Omicron Higher Than From Delta

This week the nation recorded a seven-day average of 2,200 daily coronavirus-related deaths, higher than the daily death count recorded two months ago during the Delta variant surge. WebMD Health News source https://www.medscape.com/viewarticle/967451?src=rss

Some US Women Not Getting ET for Curable Breast Cancer

A novel study shows large geospatial variations across the United States in endocrine therapy (ET) for early breast cancer, showing that many women are being undertreated. Medscape Medical News source https://www.medscape.com/viewarticle/967441?src=rss

Ocular Rosacea Symptoms Include Itch, Foreign Body Sensations

In the study, 26% of those with rosacea had conjunctival telangiectasia, compared with only 1.8% of controls. Medscape Medical News source https://www.medscape.com/viewarticle/967440?src=rss

Uptake Uncertain for Potent New Cholesterol-Lowerer Inclisiran

Inclisiran, a novel small interfering RNA drug that inhibits PCSK9, made its US debut in early 2022 with cautious uptake prospects. Medscape Medical News source https://www.medscape.com/viewarticle/967363?src=rss

Oxaliplatin Add-On Not Recommended for Elderly With Colon Cancer

The addition of oxaliplatin does not extend progression-free survival in elderly patients with metastatic colorectal cancer and in fact, can lead to more severe adverse events. Medscape Medical News source https://www.medscape.com/viewarticle/967361?src=rss

Novel Drug, First Tx for Rare Uveal Melanoma

A novel drug, the first in its class, is also the first treatment approved for use in uveal melanoma, a rare cancer of the eye, after it was shown to improve overall survival. FDA Approvals source https://www.medscape.com/viewarticle/967360?src=rss

Moderate-Vigorous Stepping Lowers Diabetes Risk in Older Women

"To the best of our knowledge, there are few studies examining the association between objectively measured steps per day and incident diabetes in a community-based setting." Medscape Medical News source https://www.medscape.com/viewarticle/967359?src=rss

Possible Contributor to COVID-19 Neurologic Manifestations

Computer analysis of human brain immune components showed that NRP1 and furin were significantly expressed in neuronal cells, suggesting that NRP1 may have a role in SARS-CoV-2 neuropathology. First Look source https://www.medscape.com/viewarticle/967358?src=rss

'Physiology Fights Back' When People Are Trying to Lose Weight

'Individuals who are struggling to achieve weight loss goals, despite assuring compliance with [a] diet, may indeed be 'suffering' from metabolic adaptation during active weight loss,' say researchers. Medscape Medical News source https://www.medscape.com/viewarticle/967318?src=rss

Are Cancer Patients Better Off in a Clinical Trial?

Many physicians believe that receiving treatment in a cancer clinical trial leads to better care and outcomes, but there is no strong evidence to support this idea. Medscape Medical News source https://www.medscape.com/viewarticle/967282?src=rss

Doctor's Illegal Opioid Prescriptions Lead to 5 Deaths: Officials

Alaskan family physician sentenced to 34 months in prison, probation; Texas hospital CEO and seven docs settle kickback allegations; practice administrator sentenced for fraudulent prescriptions. Medscape Business of Medicine source https://www.medscape.com/viewarticle/967280?src=rss

More Than 1 in 10 People in US Have Diabetes, CDC Says

According to the latest National Diabetes Statistics Report, a quarter of those with diabetes are undiagnosed and over a third of the US population has prediabetes. Medscape Medical News source https://www.medscape.com/viewarticle/967279?src=rss

High Rates of Obesity, CKD Found in Type 1 Diabetes

Rates of obesity are as high in people with type 1 diabetes as in the general population, and rates of kidney disease are higher than in people with type 2 diabetes after adjusting for age. Medscape Medical News source https://www.medscape.com/viewarticle/967248?src=rss

Alternative Birthing Practices Tied to Neonatal Infection Risk

Increasingly popular alternative peripartum practices such as water immersion and nonseverance of the umbilical cord may increase the risk of infections in newborns. Medscape Medical News source https://www.medscape.com/viewarticle/967278?src=rss

'Retinal Age Gap' Linked to Arterial Stiffness and CVD Risk

Retinal age gap, defined as age predicted from the fundus image minus chronologic age, is associated with the arterial stiffness index and may be a novel biomarker for subclinical CVD. First Look source https://www.medscape.com/viewarticle/967277?src=rss

Gut Bacteria Linked With Long COVID

'To our knowledge, this is the first study to show that altered gut microbiome is strongly associated with persistent symptoms in patients with COVID up to 6 months after clearance of SARS-CoV-2 virus.' Medscape Medical News source https://www.medscape.com/viewarticle/967195?src=rss

20% of US Population Has Been Infected With COVID

Over the past 28 days, the US had 18.3 million cases and almost 48,000 deaths. WebMD Health News source https://www.medscape.com/viewarticle/967190?src=rss

Adding TACE to Lenvatinib Improves Survival in Liver Cancer

Transarterial chemoembolization (TACE) added onto lenvatinib is a new first-line option for patients with advanced liver cancer, say LAUNCH trialists. Medscape Medical News source https://www.medscape.com/viewarticle/967184?src=rss

Pfizer CEO Sees Annual COVID Vaccine Rather Than Frequent Boosters

Pfizer Inc Chief Executive Albert Bourla said on Saturday that an annual COVID-19 vaccine would be preferable to more frequent booster shots in fighting the coronavirus pandemic. Reuters Health Information source https://www.medscape.com/viewarticle/967086?src=rss

Fourth COVID Vaccine Shot Raises Resistance to Serious Illness for Over-60s: Israel

A fourth dose of COVID-19 vaccine given to people over 60 in Israel made them three times more resistant to serious illness than thrice-vaccinated people in the same age group, Israel's Health Ministry said on Sunday. Reuters Health Information source https://www.medscape.com/viewarticle/967083?src=rss

Do Not Assume COVID Pandemic Reaching 'End Game', Warns WHO

The head of the World Health Organization warned on Monday that it was dangerous to assume the Omicron variant would herald the end of COVID-19's acutest phase, exhorting nations to stay focused to beat the pandemic. Reuters Health Information source https://www.medscape.com/viewarticle/967080?src=rss

7 Ways Doctors Could Get Better Payment From Insurers

Doctors often miss opportunities to get paid more when they sign insurance contracts to be in their networks. Experts tell how they can do better. Medscape Medical News source https://www.medscape.com/viewarticle/967183?src=rss

94% of Nurses Say There's Racism in Healthcare: Survey

Nursing leaders encourage healthcare settings to confront individual, systemic racism to drive change. Medscape Medical News source https://www.medscape.com/viewarticle/967178?src=rss

Is COVID Retreating in the US? Data Paints Encouraging Scenario

New coronavirus cases are falling in parts of the United States hit hardest by the fast-spreading Omicron variant, according to a Reuters analysis of public health data, offering an early indication the virus might once again be in retreat. Reuters Health Information source https://www.medscape.com/viewarticle/967037?src=rss

Italy to Set Aside 150 Mln Euros for COVID Vaccination Compensation

Italy plans to set aside 150 million euros to compensate those suffering side effects from COVID-19 vaccinations, a draft decree seen by Reuters showed on Friday. Reuters Health Information source https://www.medscape.com/viewarticle/967018?src=rss

WHO Recommends Reduced Dose Pfizer COVID Vaccine for Under 12s

The World Health Organization on Friday recommended extending the use of a reduced dosage of Pfizer's COVID-19 vaccine to children aged 5 to 11 years old. Reuters Health Information source https://www.medscape.com/viewarticle/967017?src=rss

OTC Cannabidiol Products Tied to Improved Pain, Sleep, Anxiety

Over-the-counter cannabidiol products appear to improve pain, sleep, and anxiety disorders, preliminary research suggests. Medscape Medical News source https://www.medscape.com/viewarticle/967088?src=rss

US FDA Declines to Approve Growth Hormone Deficiency Treatment

The US health regulator has declined to approve the treatment for growth hormone deficiency in children that Pfizer developed with partner OPKO Health. Reuters Health Information source https://www.medscape.com/viewarticle/967079?src=rss

Dual Immunotherapy Promising New Option for Liver Cancer

The combination of durvalumab plus the experimental drug tremelimumab significantly improved overall survival as compared to sorafenib. Medscape Medical News source https://www.medscape.com/viewarticle/967077?src=rss

Phase 2 Studies of Novel JAK1 Inhibitor for HS Show Promise

Results of the two phase 2 studies "establish proof of concept" for the JAK1 inhibitor for the treatment of moderate to severe hidradenitis suppurativa, the investigators concluded. Medscape Medical News source https://www.medscape.com/viewarticle/967076?src=rss

Decipher Scores Help Predict Upgrade on PCa Active Surveillance

The findings only apply to Gleason grade group 1 disease. The study covered in this summary was published on medrxiv.org as a preprint and has not yet been peer reviewed. First Look source https://www.medscape.com/viewarticle/967075?src=rss

How Omicron Highlights Fading Hope of Herd Immunity From COVID

The Omicron variant is not likely to help countries achieve so-called herd immunity against COVID-19, in which enough people become immune to the virus that it can no longer sustain transmission, leading disease experts say. Reuters Health Information source https://www.medscape.com/viewarticle/966929?src=rss

Cheap Version of Merck COVID Pill to Be Made for Poorer Nations

A UN-backed agency has struck a deal for nearly 30 generic drugmakers to make low-cost versions of Merck & Co's COVID-19 pill molnupiravir for poorer nations, widening access to a drug seen as a weapon in fighting the pandemic. Reuters Health Information source https://www.medscape.com/viewarticle/966924?src=rss

Physician Burnout, Depression Compounded by COVID: Survey

Doctors were already struggling with burnout; the COVID-19 pandemic didn't help. Medscape Medical News source https://www.medscape.com/viewarticle/966996?src=rss

One Third of Connective Tissue Diseases Trials Go Unpublished

Smaller studies were more likely than larger studies to be discontinued or unpublished. Medscape Medical News source https://www.medscape.com/viewarticle/966993?src=rss

Herd Immunity a Mirage? High Protection Didn't Stop Surges

An estimated 72% of Los Angeles County residents had been vaccinated and/or had been previously infected as of last April, study says, but Delta/Omicron still hit hard. Medscape Medical News source https://www.medscape.com/viewarticle/966991?src=rss

Peanut Oral Immunotherapy Works in Toddlers: IMPACT Trial

After 2.5 years of peanut oral immunotherapy, 71% of toddlers could safely consume 17 peanuts, and more than 1 in 5 maintained this protection even after stopping treatment for 6 months. Medscape Medical News source https://www.medscape.com/viewarticle/966990?src=rss

How the Pandemic Led to Disarray ― and Discovery

In the scramble to tackle the virus in real time, entrenched scientific and medical processes were challenged, sometimes leading to mixed results. Medscape Medical News source https://www.medscape.com/viewarticle/966838?src=rss

The Virus Within: How Misinformation Made the Pandemic Worse

Based in lack of trust that is often fanned by politicians, the media, and others, misinformation has not only caused arguments but arguably has also cost many lives. Medscape Medical News source https://www.medscape.com/viewarticle/966829?src=rss

The Pandemic Has Changed Us, Permanently

Over the past 2 years, Americans have made many changes to how they live, work, play, worship ― and manage their health. Many experts think some of these changes are here to stay. Medscape Medical News source https://www.medscape.com/viewarticle/966875?src=rss

COVID-19 Survivors and Experts Share Pandemic 'Silver Linings'

'Benefit finding' is a skill among some of the more resilient people whose lives have been upended by COVID-19, and experts explain how it can help others. Medscape Medical News source https://www.medscape.com/viewarticle/966899?src=rss

Fauci: 'Open Question' Whether Omicron Ends Pandemic

It's much too early to say if the Omicron variant signals the end of the COVID-19 pandemic, Anthony Fauci, MD, said. WebMD Health News source https://www.medscape.com/viewarticle/966820?src=rss

Patient Satisfaction: Is It Overrated?

Physicians debate the usefulness of patient satisfaction surveys. Some consider them helpful, others feel they're worthless. Medscape Medical News source https://www.medscape.com/viewarticle/966817?src=rss

WHO Says No Evidence Healthy Children, Adolescents Need COVID-19 Boosters

There is no evidence at present that healthy children and adolescents need booster doses of COVID-19 vaccine, the World Health Organization's chief scientist Soumya Swaminathan said on Tuesday. Reuters Health Information source https://www.medscape.com/viewarticle/966771?src=rss

EU Watchdog Urges Vaccine Developers Not to Focus Only on Omicron

The European Union drugs regulator said pharmaceuticals companies should work on more than one upgraded COVID-19 shot, not only tailored to the fast-emerging Omicron variant but also versions that address a combination of variants. Reuters Health Information source https://www.medscape.com/viewarticle/966764?src=rss

EU Regulator Finds mRNA COVID-19 Shots Safe During Pregnancy

COVID-19 vaccines made using mRNA technology do not cause pregnancy complications for expectant mothers and their babies, the European Union's drug regulator said on Tuesday. Reuters Health Information source https://www.medscape.com/viewarticle/966751?src=rss

Appendectomy or Antibiotics? Large Trial Helps Decision Making

A study reinforces a link between appendicoliths and appendectomies after antibiotics, but its author said there's a surprising lack of connection for other factors that tilt patients toward surgery. Medscape Medical News source https://www.medscape.com/viewarticle/966810?src=rss

Pediatric CAP: Short 5-Day Antibiotic Course Beats 10-Day

Treatment of uncomplicated pediatric community-acquired pneumonia with a short, 5-day course of antibiotics results in a superior clinical response compared to the standard 10-day course. Medscape Medical News source https://www.medscape.com/viewarticle/966806?src=rss

Pathological Complete Response Likely Not a Reliable Survival Surrogate in Early Breast Cancer

A new meta-analysis suggests that pathological complete response should not be used as a surrogate endpoint in randomized trials of neoadjuvant therapies for early breast cancer. Reuters Health Information source https://www.medscape.com/viewarticle/966719?src=rss

Vaccine-Like mRNA Injection Effectively Treats Cardiac Fibrosis in Mice

A vaccine-like injection of modified mRNA temporarily reprogrammed immune cells to attack fibroblasts in a mouse model of heart failure, resulting in 'marked functional improvement,' researchers say. Reuters Health Information source https://www.medscape.com/viewarticle/966718?src=rss

Risankizumab Effective Against Refractory Psoriatic Arthritis

The IL-23 inhibitor provides some relief for patients with active psoriatic arthritis whose symptoms have responded poorly to standard treatments, according to 24-week results of a phase 3 trial. Reuters Health Information source https://www.medscape.com/viewarticle/966708?src=rss

Data for Omicron-Specific Shot Likely Available in March: Moderna

Moderna's vaccine candidate against the Omicron coronavirus variant will enter clinical development in the next few weeks, CEO Stephane Bancel said on Monday. Reuters Health Information source https://www.medscape.com/viewarticle/966705?src=rss

Long-Term Adjunctive Edaravone for ALS: Latest Findings

Adding IV edaravone to riluzole for a year provides no additional benefit in terms of amyotrophic lateral sclerosis progression, time to ventilation, or survival versus riluzole alone, new research shows. Medscape Medical News source https://www.medscape.com/viewarticle/966717?src=rss

Aduhelm Ancillary Costs to Push Medicare Spending Even Higher

A new cost analysis taking into account spending on ancillary health services suggests that prior cost analyses underestimated the anticipated costs of aducanumab. Medscape Medical News source https://www.medscape.com/viewarticle/966710?src=rss

Anemia in Astronauts Could Be a Challenge for Space Missions

The next 'giant leap' for humans may be a trip to Mars, but having enough oxygen-carrying red blood cells for the journey might present a challenge, new research suggests. Reuters Health Information source https://www.medscape.com/viewarticle/966648?src=rss

More Omicron Hospitalizations in Youngest Children, but Cases Mild

Infants under 12 months of age are proportionally more likely to be hospitalized with the Omicron variant of the coronavirus than older children but they do not become particularly sick, British researchers said. Reuters Health Information source https://www.medscape.com/viewarticle/966629?src=rss

TPVR, Surgery Appear to Have Comparable Outcomes

Patients who undergo TPVR face similar odds of surviving and not needing reintervention or surgery as those who undergo surgical conduit or valve replacement, according to new findings. Reuters Health Information source https://www.medscape.com/viewarticle/966624?src=rss

Grasping Social Cognition May Be Critical in Treating Epilepsy

Review sheds light on predictors of social cognitive impairment in this population. First Look source https://www.medscape.com/viewarticle/966703?src=rss

Higher Cardiorespiratory Fitness Cuts Incident Diabetes Risk

A single-center, retrospective, observational study of more than 8700 adults in Saudi Arabia showed that increased cardiorespiratory fitness reduced the risk for incident type 2 diabetes. Medscape Medical News source https://www.medscape.com/viewarticle/966702?src=rss

Omicron Surge Pushing US Healthcare System to the Limit

As hospitals fill with patients again, experts and workers say damage to the industry may be long-lasting. "It has exploded. We're in a crisis, red-tier situation again." WebMD Health News source https://www.medscape.com/viewarticle/966608?src=rss

'Space Medicine' Returns to Earth

New medical technology developed for NASA astronauts is helping earthbound physicians and their patients. Medscape Medical News source https://www.medscape.com/viewarticle/966607?src=rss

MedPAC Draws AMA Ire With Vote on 2023 Physician Pay

An influential federal panel gave its okay to a mandated freeze on a base rate for Medicare clinician pay but sought to revisit this issue in the future. Medscape Medical News source https://www.medscape.com/viewarticle/966606?src=rss

Disparities in GLP-1 Receptor Agonist Use in Type 2 Diabetes

White and more affluent patients with type 2 diabetes are significantly more likely to receive GLP-1 receptor agonist therapy than individuals who are Black, Asian, Hispanic or low-income, a US study suggests. Reuters Health Information source https://www.medscape.com/viewarticle/966590?src=rss

Incident Anorexia Among Youth Increased During COVID-19 Pandemic

The incidence and severity of new-onset anorexia nervosa increased among children and adolescents during the COVID-19 pandemic, a Canadian study suggests. Reuters Health Information source https://www.medscape.com/viewarticle/966587?src=rss

Court Suspends Order to Wear Masks Outdoor in Paris

A French administrative tribunal on Thursday suspended an order that masks be worn on the streets of Paris, news agency AFP reported. Reuters Health Information source https://www.medscape.com/viewarticle/966586?src=rss

Biogen Seeks Dialogue With US CMS About Alzheimer's Drug Coverage Decision

Biogen's chief executive officer on Thursday said the company wants a dialogue with the CMS ahead of a final decision on coverage of its controversial Alzheimer's disease drug in April. Reuters Health Information source https://www.medscape.com/viewarticle/966555?src=rss

Epstein-Barr Virus a Likely Leading Cause of Multiple Sclerosis

Epstein-Barr virus is the likely cause of multiple sclerosis, new research confirms. Investigators found the risk of MS increased 32-fold following EBV infection. Medscape Medical News source https://www.medscape.com/viewarticle/966604?src=rss

Radiation Oncology: More Women Now, but Numbers Still Low

Although recent years have seen more women, minorities remain particularly underrepresented in senior faculty positions in radiation oncology. Medscape Medical News source https://www.medscape.com/viewarticle/966601?src=rss

BRCA Testing Underused in Women With Ovarian Cancer

More than a decade after calls for universal screening for germline BRCA mutations in women with ovarian cancer, it remains underused. Medscape Medical News source https://www.medscape.com/viewarticle/966600?src=rss

Neuromap Toolbox Revolutionizes Brain-Mapping Data Interpretation

A novel open-source Python software package gives human brain–mapping researchers a set of standardized workflows to aid interpretation of their data and facilitate interdisciplinary collaboration. First Look source https://www.medscape.com/viewarticle/966599?src=rss

US COVID Deaths Rising but Likely Due to Delta, Not Omicron, Says CDC Chief

COVID-19 hospitalizations in the United States have increased by about 33% and deaths are up by about 40% from a week earlier, the head of the US CDC said on Wednesday. Reuters Health Information source https://www.medscape.com/viewarticle/966485?src=rss

Valencia Health Body Guilty of Neglecting COVID Medics

A Spanish court on Wednesday ordered a regional health authority to compensate scores of doctors for failing to protect them adequately against infection risk during the COVID-19 pandemic's first and most lethal wave. Reuters Health Information source https://www.medscape.com/viewarticle/966468?src=rss

COVID-19 Booster Can Be Given With Pneumonia Shot: Pfizer Study

Pfizer has said that booster doses of its COVID-19 vaccine can be administered along with its pneumonia vaccine and produced strong safety and immune responses in people aged 65 and older in a late-stage study. Reuters Health Information source https://www.medscape.com/viewarticle/966453?src=rss

FDA Head: 'Most People Are Going to Get COVID'

"I think it's hard to process what's actually happening right now, which is most people are going to get COVID." WebMD Health News source https://www.medscape.com/viewarticle/966524?src=rss

Staff Shortages Force United to Cut Flights

United Airlines is responding to the surge in COVID cases by cutting an unspecified number of flights to "make sure we have the staffing and resources to take care of our customers." WebMD Health News source https://www.medscape.com/viewarticle/966522?src=rss

ACIP Releases New Dengue Vaccine Recommendations

Sanofi's Dengvaxia has been recommended for use in the US by the CDC's Advisory Committee on Immunization Practices Medscape Medical News source https://www.medscape.com/viewarticle/966519?src=rss

Overweight, Obesity in Early Adulthood Tied to Higher Risk of Early Onset Colorectal Cancer

People who are overweight or obese in their 20s are at increased risk of developing early onset colorectal cancer, researchers in Germany report. Reuters Health Information source https://www.medscape.com/viewarticle/966410?src=rss

WHO Body Says COVID-19 Vaccines May Need to Be Updated for Omicron

A WHO technical body said on Tuesday that current COVID-19 vaccines may need to be reworked to ensure they are effective against Omicron and future variants of the coronavirus. Reuters Health Information source https://www.medscape.com/viewarticle/966394?src=rss

PharmaMar Shares Soar After Drug Study Suggests Efficacy Against Omicron

Shares in PharmaMar jumped almost 20% on Tuesday after the Spanish drugmaker said lab trials suggested its Plitidepsin drug was effective against the main COVID-19 variants, including the highly contagious Omicron. Reuters Health Information source https://www.medscape.com/viewarticle/966392?src=rss

South African Studies Suggest Omicron Has Higher 'Asymptomatic Carriage'

Preliminary findings from two South African clinical trials suggest the Omicron coronavirus variant has a much higher rate of 'asymptomatic carriage' than earlier variants. Reuters Health Information source https://www.medscape.com/viewarticle/966383?src=rss

Too Soon to Treat COVID-19 Like Flu as Omicron Spreads: WHO

The Omicron variant of COVID-19 is on track to infect more than half of Europeans, but it should not yet be seen as a flu-like endemic illness, the World Health Organization (WHO) said on Tuesday. Reuters Health Information source https://www.medscape.com/viewarticle/966382?src=rss

Physicians React: Docs Lose Licenses for False COVID Information

Doctors have strong feelings about possible repercussions for physicians who disseminate inaccurate information about COVID-19. Here's what they have to say. Medscape Medical News source https://www.medscape.com/viewarticle/966449?src=rss

Europe Loosens COVID Policies as Omicron Takes Out Key Workers

The Czech Republic said on Monday it would allow critical workers such as doctors and teachers to go to work after a positive COVID-19 test, the latest European country to ease restrictions to keep services running as cases surge. Reuters Health Information source https://www.medscape.com/viewarticle/966308?src=rss

Much Lower Risk of False Positive Breast Screen in Norway vs US

New data from Norway show that close to 1 in 5 women will experience a false positive result on screening mammography if they attend 10 biennial screening rounds — a lower risk than reported in the US. Medscape Medical News source https://www.medscape.com/viewarticle/966378?src=rss

Handing It Down: The Craft of Indigenous Healing

Former midwife Marika Alvarado, a Native American healer, fulfills her destiny by passing on her knowledge of traditional medicine to others. Medscape Medical News source https://www.medscape.com/viewarticle/966375?src=rss

It's Never Too Late to Quit Smoking, Even After Lung Cancer Diagnosis

Quitting smoking after a lung-cancer diagnosis confers a significant survival benefit, according to results of a meta-analysis. Reuters Health Information source https://www.medscape.com/viewarticle/966323?src=rss

Mayo Classification by US Useful for Rare Kidney Disease

The Mayo classification of autosomal dominant polycystic kidney disease based on ultrasound rather than MRI findings performs well, report clinicians from Spain. Reuters Health Information source https://www.medscape.com/viewarticle/966321?src=rss

HPV Testing Plus Cytology Catches Two Times More Cervical Lesions

Despite major loss to follow-up, a Mexican study confirms the importance of HPV testing for early detection of high-grade cervical lesions compared to cytology alone. Medscape Medical News source https://www.medscape.com/viewarticle/966373?src=rss

Blood Test Better Predicts Benefit From Lung Cancer Screening

A blood-based biomarker test combined with a lung cancer risk model was better at predicting who could benefit most from lung cancer screening. Medscape Medical News source https://www.medscape.com/viewarticle/966305?src=rss

As Pandemic Regs Expire, States Get Tougher on Telehealth: Report

In some states, insurers no longer have to cover telehealth; difficulties also linger for practicing medicine across jurisdictions. Medscape Medical News source https://www.medscape.com/viewarticle/966297?src=rss

FDA OKs New Adult Insomnia Med

The approval was based on a phase 3 trial showing daridorexant was associated with improved sleep onset, sleep maintenance, and daytime functioning in adults with insomnia. FDA Approvals source https://www.medscape.com/viewarticle/966295?src=rss

THINKER-NEXT Studies the Transplant of HCV-Infected Kidneys

THINKER-NEXT trial aims to determine the risks and benefits of transplanting kidneys from hepatitis C-infected donors into hepatitis C-negative recipients. Medscape Medical News source https://www.medscape.com/viewarticle/966292?src=rss

Neutralizing Antibody Response to Yellow Fever Vaccination Attenuated in South America

The yellow fever virus vaccine may not do as well at neutralizing the current Brazilian strain as it does against the virulent strain in Africa, researchers say. Reuters Health Information source https://www.medscape.com/viewarticle/966286?src=rss

Blacks With Head and Neck Cancer Likely Have Worse Outcomes

In a retrospective study of racial/ethnic minorities with head and neck cancer, Blacks had worse outcomes, and researchers are not sure why. Reuters Health Information source https://www.medscape.com/viewarticle/966284?src=rss

UK Says Booster Shots Still Protecting Older People Against Omicron

Booster jabs are continuing to provide high levels of protection against severe disease from the Omicron coronavirus variant among older adults, say British health officials. Reuters Health Information source https://www.medscape.com/viewarticle/966265?src=rss

Physical Therapy Timing Matters After Rotator Cuff Repair

Following rotator cuff repair, it might be best to delay the start of physical therapy by at least 1 week, a new study hints. Reuters Health Information source https://www.medscape.com/viewarticle/966239?src=rss

Oral Octreotide Shows Promise as Alternative to Injections for Acromegaly

Many patients with acromegaly may do as well on oral octreotide treatment as they do on injectable somatostatin receptor ligands, an industry-sponsored phase 3 trial suggests. Reuters Health Information source https://www.medscape.com/viewarticle/966233?src=rss

COVID-19 Associated With Increased Diabetes Risk in Youth

Two large databases indicate significantly increased diabetes risk among those with COVID-19 but not other acute respiratory illnesses. Medscape Medical News source https://www.medscape.com/viewarticle/966291?src=rss

AHA Advice for Diabetes Patients to Stay Heart Healthy

Fewer than 1 in 5 in the US meet targets for blood sugar, blood pressure, and lipids. Medscape Medical News source https://www.medscape.com/viewarticle/966290?src=rss

COVID-19 Vaccine Responses Vary Among Hematological Malignancies

A systematic review and meta-analysis of 44 clinical studies published between January and August 2021, finds an overall reasonable response to COVID-19 vaccinations for patients with underlying hematological malignancies. The authors describe an urgent need for more effective regimens for high-risk patients. The study was made available as a preprint on medRxiv on November 8, 2021, and has not ye First Look source https://www.medscape.com/viewarticle/966288?src=rss

Levetiracetam May Improve Survival in Patients With Glioblastoma

Adding levetiracetam to standard of care led to better survival overall, but certain patient subgroups may derive a greater benefit, according to a preprint study that has not yet been peer-reviewed. First Look source https://www.medscape.com/viewarticle/966253?src=rss

South Dakota Makes It Harder for Women to Get Abortion Meds

South Dakota lawmakers on Thursday approved Gov. Kristi Noem's new rule for medical abortions that makes the state one of the hardest places in the US to get abortion pills. Associated Press source https://www.medscape.com/viewarticle/966250?src=rss

Omit Periop Chemo in Mismatch Repair Deficient Gastric Cancer

Patients with mismatch repair deficient gastric cancer demonstrated better median overall survival when skipping perioperative chemotherapy, according to a preprint study. First Look source https://www.medscape.com/viewarticle/966249?src=rss

Chicago Nixes School for 3rd Day as Virus, Union Debate Rage

The union, which voted this week to revert to online instruction, told teachers not to show up to schools starting Wednesday during the latest COVID-19 surge while both sides negotiate. Associated Press source https://www.medscape.com/viewarticle/966243?src=rss

Lack of High School Education Vaccine Hesitancy Predictor

Researchers from the University of North Carolina looked at vaccination rates in 3142 counties in the US. They compared them to population characteristics based on the CDC Social Vulnerability Index. WebMD Health News source https://www.medscape.com/viewarticle/966234?src=rss

Live Donors for First Kidney Transplant Improve Kids' Life-Years

Pediatric patients whose first kidney transplant is from a live donor show improved life years over those whose first kidney transplant is a deceased donor. Medscape Medical News source https://www.medscape.com/viewarticle/966229?src=rss

COVID-19 Vaccination Has Little Impact on Menstrual Cycle

The issue is significant, as regular menstruation is a sign of health and fertility, and fears of disturbances might increase vaccination hesitancy as COVID-19 cases continue to surge. Medscape Medical News source https://www.medscape.com/viewarticle/966238?src=rss

Medicare Funds for NP Training Address Nursing Shortage: Study

A new study shows Medicare support of clinical training for nurse practitioners greatly boosted the number of primary care NPs graduating from participating nursing schools, and could stem shortages. Medscape Medical News source https://www.medscape.com/viewarticle/966228?src=rss

Students Lead Reform When It Comes to Med School Racial Inequity

Medical school leaders say they are seeing new momentum in students demanding changes in curricula and medical assumptions and acknowledgment of medicine's dark racial past. Medscape Medical News source https://www.medscape.com/viewarticle/966223?src=rss

Gavi and India's Bharat Discuss Possible COVAX Use of Covaxin

The Gavi vaccine alliance is in talks with India's Bharat Biotech over potential procurement of the company's Covaxin COVID-19 shot for the COVAX global vaccine distribution programme, a Gavi spokesperson said Thursday. Reuters Health Information source https://www.medscape.com/viewarticle/966141?src=rss

Antibody Therapy Effective in Immunodeficient COVID-19 Patients

Patients with immunodeficiency-associated antibody disorders and a longstanding SARS-CoV-2 infection improved substantially after receiving compassionate-use casirivimab and imdevimab, a new study shows. Reuters Health Information source https://www.medscape.com/viewarticle/966136?src=rss

Infections at Record High, Hospitalizations Low as Omicron Sweeps Israel

Data from Israel on Thursday supported growing evidence worldwide that Omicron causes milder illness than previous variants of the coronavirus even as the country grappled with a record number of daily infections. Reuters Health Information source https://www.medscape.com/viewarticle/966134?src=rss

I Saw Firsthand What It Takes to Keep COVID Out of Hong Kong

On a visit to Hong Kong, ProPublica reporter Caroline Chen encountered a 21-day quarantine, a bevy of COVID tests, universal masking, and, finally, a fear-free family holiday. ProPublica source https://www.medscape.com/viewarticle/966146?src=rss

Fallopian Organoids Promising for Ovarian Cancer Prediction

Fallopian tube organoids hold the potential for predicting the development of ovarian cancer years in advance, researchers say. Reuters Health Information source https://www.medscape.com/viewarticle/966113?src=rss

Trudeau Says Canadians Angered at Antivaxxers; Promises More Tests

Canadians are angered by people who are not vaccinated against COVID-19, Prime Minister Justin Trudeau said on Wednesday, and he also promised more than 100 million rapid tests will be distributed quickly to provinces. Reuters Health Information source https://www.medscape.com/viewarticle/966099?src=rss

New Bird Flu Has Higher Risk of Spread to Humans: Expert

A wave of bird flu in Asia and Europe has a greater risk of spreading to humans because of a high number of variants, the World Organisation for Animal Health (OIE) said. Reuters Health Information source https://www.medscape.com/viewarticle/966084?src=rss

Macron's Blunt Language on France's Unvaccinated Causes Furore

The government on Wednesday defended President Emmanuel Macron's use of coarse language in a stepped-up campaign against France's unvaccinated. Reuters Health Information source https://www.medscape.com/viewarticle/966090?src=rss

Dynamic Duo: Identical Twins Never Stray From Shared Nursing Path

Lifelong learners and caretakers, these inseparable sisters graduated from a part-time nursing program and now plot their nursing careers, which include residency and a second doctorate. Medscape Medical News source https://www.medscape.com/viewarticle/966133?src=rss

US Jury's Mixed Theranos Verdict Complicates Potential Appeal

Theranos founder Elizabeth Holmes is likely to appeal her conviction, but four legal experts say the fact that the jury acquitted her or failed to reach a verdict on several counts could work against her. Reuters Health Information source https://www.medscape.com/viewarticle/965998?src=rss

US Court Revives Lawsuit Against Pfizer, Others on Iraq Terrorism Funding Claims

A US appeals court has revived a lawsuit against AstraZeneca, Pfizer, and other companies over allegations their contracts with Iraq's health ministry helped fund terrorism that killed Americans during the war in Iraq. Reuters Health Information source https://www.medscape.com/viewarticle/965997?src=rss

Pfizer to Supply US With 10 Mln More Courses of COVID-19 Pills

The Biden administration has doubled its order for Pfizer's oral COVID-19 antiviral treatment, the company and the White House said on Tuesday. Reuters Health Information source https://www.medscape.com/viewarticle/965992?src=rss

Fourth COVID-19 Vaccine Dose Boosts Antibodies Fivefold in Israeli Study, PM Says

A fourth dose of COVID-19 vaccine boosts antibodies five-fold a week after the shot is administered, Israeli Prime Minister Naftali Bennett said on Tuesday, citing preliminary findings of an Israeli study. Reuters Health Information source https://www.medscape.com/viewarticle/965991?src=rss

Do COVID-19 Outcomes Among Cancer Patients Vary Across the US?

Rates of mechanical ventilation, ICU admission, or death did not differ significantly among patients with cancer and COVID-19 across different regions of the United States, according to new registry data. Reuters Health Information source https://www.medscape.com/viewarticle/965990?src=rss

COVID-19 Boosters Every Few Months Not Sustainable, UK Science Adviser Says

It is not sustainable to give COVID-19 booster shots every 3 to 6 months in the long term, Britain's chief scientific adviser said on Tuesday. Reuters Health Information source https://www.medscape.com/viewarticle/965982?src=rss

Coronavirus Leaves Survivors With Autoantibodies

Months after recovering from SARS-CoV-2 infection, survivors have elevated levels of autoantibodies, even if they had not been severely ill, according to new findings. Reuters Health Information source https://www.medscape.com/viewarticle/965930?src=rss

Viral Medicine: Top Online Healthcare Moments of 2021

From ivermectin use to 'dry scooping,' social media provided a lot of varied healthcare advice for doctors to dispel in 2021. Medscape Medical News source https://www.medscape.com/viewarticle/965944?src=rss

FDA Lifts Restrictions on Spinal Cord Stimulation System

Expanded MRI compatibility will allow more patients implanted with the Proclaim XR SCS system to obtain MRI scans when needed ― and increases efficiencies for radiologists, the manufacturer notes. Medscape Medical News source https://www.medscape.com/viewarticle/965943?src=rss

Sewage Survey Shows Omicron Spreading to Most Regions in Italy

A survey of wastewater showed the Omicron coronavirus variant spreading to a majority of regions of Italy in December, the government's National Health Institute said on Monday. Reuters Health Information source https://www.medscape.com/viewarticle/965885?src=rss

Interval Between Moderna COVID-19 Vaccine Second Shot and Booster Still 6 Months: FDA

The interval between receiving a second dose of Moderna's COVID-19 vaccine and a booster dose remains unchanged at 6 months, US Food and Drug Administration Acting Commissioner Janet Woodcock said on Monday. Reuters Health Information source https://www.medscape.com/viewarticle/965882?src=rss

'We Will Not Yield,' French Lawmaker Says After Death Threats Over COVID Vaccine Pass

French lawmakers said on Monday they would not be cowed by death threats that dozens of them received over a bill that will require people to show proof of vaccination to go to a restaurant or cinema or take the train. Reuters Health Information source https://www.medscape.com/viewarticle/965871?src=rss

US Tops 1 Million Daily COVID-19 Cases

Monday's unfortunate tally is almost double the previous domestic record of 590,000 set just 4 days ago. WebMD Health News source https://www.medscape.com/viewarticle/965941?src=rss

High-Altitude Exercise May Harm Blood Sugar Control in T1DM

People with type 1 diabetes may need to monitor their blood sugar more closely when participating in high-altitude activities such as hiking or skiing, according to results of a small study. Reuters Health Information source https://www.medscape.com/viewarticle/965667?src=rss

COVID-19 Outbreak Hits Research Station in Antarctica

Two thirds of the 25 workers have tested positive at the station, despite all of them being fully vaccinated and going through several testing stages being allowed entrance. WebMD Health News source https://www.medscape.com/viewarticle/965937?src=rss

Less Burdensome Growth-Hormone Replacement With Once-Weekly Somapacitan in Children

For replacement of endogenous growth hormone in children with growth-hormone deficiency, a once-weekly injection somapacitan was safe and effective over 3 years in a phase 2 randomized controlled trial. Reuters Health Information source https://www.medscape.com/viewarticle/965864?src=rss

Florida Breaks Single-Day COVID-19 Record With 75,900 Cases

It breaks the record set a day earlier when more than 58,000 cases were reported in the state. Associated Press source https://www.medscape.com/viewarticle/965877?src=rss

Taking a Step Back: US Colleges Returning to Online Classes

Many colleges hope that an extra week or two will get them past the peak of the nationwide spike driven by the highly contagious omicron variant. Associated Press source https://www.medscape.com/viewarticle/965873?src=rss

Medicaid Implements Waivers for Some Clinical Trial Coverage

This year, CMS will help implement a mandate for Medicaid coverage of costs associated with clinical trial participation, a move expected to increase Black and Hispanic enrollment in studies. Medscape Medical News source https://www.medscape.com/viewarticle/965866?src=rss

Crohn's Strictures May Respond to Immunosuppressive Drug Therapy

Symptomatic strictures related to Crohn's disease may respond to immunosuppressive drug therapy, with improvements in symptoms and stricture morphology, according to results of a study from Australia. Reuters Health Information source https://www.medscape.com/viewarticle/965845?src=rss

UK Had Over 2 Million COVID-19 Cases in Week to December 23: Official Estimate

More than 2 million people in Britain tested positive for COVID-19 in the week before Christmas, Office for National Statistics estimates published on Friday showed, with the highest ratio of around one in 25 people seen in England. Reuters Health Information source https://www.medscape.com/viewarticle/965837?src=rss

Greater Intestinal Permeability Seen With Bile Acid Diarrhea Than IBS Diarrhea

People with bile acid diarrhea may have more permeable intestines than people with irritable bowel syndrome diarrhea, a new study suggests. Reuters Health Information source https://www.medscape.com/viewarticle/965814?src=rss

Sleeping Position Matters in Patients With GERD

The position in which a person with gastroesophageal reflux disease sleeps appears to have an impact on the occurrence of reflux symptoms during the night, according to a small study that suggests lying on the left side is best. Reuters Health Information source https://www.medscape.com/viewarticle/965790?src=rss

Triple Therapy Provides Robust and Durable Benefits in Cystic Fibrosis

Triple combination therapy with elexacaftor, ivacaftor, and tezacaftor has advantages over tezacaftor plus ivacaftor in people with cystic fibrosis, according to results of a phase 3b trial. Reuters Health Information source https://www.medscape.com/viewarticle/965830?src=rss

Reward Processing Disrupted in Parkinson's Disease, Tied to Dopamine Therapy, Psychiatric Disorders

Reward processing impairment in Parkinson's disease differs depending on the type of reward and the patient's dopamine medication state (on or off), a systematic review and meta-analysis suggests. Reuters Health Information source https://www.medscape.com/viewarticle/965829?src=rss

Drop in PSA Tied to Better Outcomes of Apalutamide Therapy in Prostate Cancer

Adding apalutamide to androgen-deprivation therapy leads to a fast, sustained drop in PSA levels in patients with nonmetastatic castration-resistant prostate cancer, and this reduction is linked with better outcomes, according to a post hoc analysis of data from the SPARTAN trial. Reuters Health Information source https://www.medscape.com/viewarticle/965785?src=rss