Posts

Mirvetuximab Signals a New Era in Ovarian Care

Mirvetuximab’s approval for FR alpha-positive, platinum-resistant disease marks a precision-medicine milestone, opening opportunities for ADCs while highlighting the need for assay standardization and safety plans. Medscape News Europe source https://www.medscape.com/viewarticle/mirvetuximab-signals-new-era-ovarian-care-2026a1000g48?src=rss

Hydronephrosis on USG Predicts Stones but May Not Cut CT Use

Hydronephrosis identified on point-of-care ultrasound is linked to higher risks for stone disease and early urologic intervention in suspected renal colic but not with reduced CT use or ED stays. Medscape Medical News source https://www.medscape.com/viewarticle/hydronephrosis-renal-point-care-ultrasound-predicts-stones-2026a1000fvn?src=rss

Hidradenitis Suppurativa Tied to Higher Cardiovascular Risks

Individuals with HS show higher risks for cardiovascular outcomes, including hypertension, coronary or ischemic heart disease, venous thromboembolism, and myocardial infarction, in a meta-analysis. Medscape Medical News source https://www.medscape.com/viewarticle/hidradenitis-suppurativa-linked-increased-cardiovascular-2026a1000fw3?src=rss

Screening for testicular cancer is ineffective

In adolescent and young adult males, palpation of the testicles for signs of cancer has traditionally been part of the preparticipation sports physical or well-child examination. Unlike most malignancies that predominantly affect older adults, testicular cancer is most commonly diagnosed between 15 and 34 years of age . Nonetheless, screening for testicular cancer has long been something I have discouraged my students and residents from doing. The rationale is twofold: it's rare, so screening will lead to many false positives and unnecessary evaluations; and more importantly, it's curable even at advanced stages, so earlier detection provides little to no incremental benefit. These were the reasons why in 2011, the U.S. Preventive Services Task Force (USPSTF)  reaffirmed its previous recommendation against testicular cancer screening , based on an evidence review that I co-authored that found no new evidence to change this conclusion. Others have dissented over the years. They...

Housing Instability Tied to Lower Rates of CRC Screening

Unmet health-related social needs, especially housing instability and transportation barriers, are linked to lower rates of screening for colorectal cancer among US adults. Medscape Medical News source https://www.medscape.com/viewarticle/housing-instability-tied-lower-rates-screening-colorectal-2026a1000fq8?src=rss

Implanted Islet Cell Device Could Control Glucose for Weeks

Researchers developed a battery-free device the size of a coin that can deliver islet cells in the body and keep them healthy, no immunosuppression required. Medscape Medical News source https://www.medscape.com/viewarticle/implanted-islet-cell-device-could-control-glucose-weeks-2026a1000fjv?src=rss

Optimal Sleep May Lower Dementia Risk in Focal Epilepsy

Optimal sleep duration is tied to better cognition and a lower risk for dementia in adults with focal epilepsy than in healthy individuals, new research shows. Medscape Medical News source https://www.medscape.com/viewarticle/optimal-sleep-may-lower-dementia-risk-focal-epilepsy-2026a1000fjr?src=rss